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Categories: Biology: Genetics, Ecology: Sea Life
Published Scientists slow aging by engineering longevity in cells
(via sciencedaily.com) Original source Researchers have developed a biosynthetic 'clock' that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
Published Genomes from 240 mammal species explain human disease risks
(via sciencedaily.com) Original source Why is it that certain mammals have an exceptional sense of smell, some hibernate, and yet others, including humans, are predisposed to disease? A major international research project has surveyed and analyzed the genomes of 240 different mammals. The results show how the genomes of humans and other mammals have developed over the course of evolution. The research shows which regions have important functions in mammals, which genetic changes have led to specific characteristics in different species and which mutations can cause disease.
Published One famous dog and a powerful new approach for understanding biology and evolutionary history
(via sciencedaily.com) Original source Ever since scientists first read the complete genetic codes of creatures like fruit flies and humans more than two decades ago, the field of genomics has promised major leaps forward in understanding basic questions in biology. Two recent articles break new ground by showing how much valuable information can be found in genomes of a single species, such as endangered orcas, or even in the DNA of an individual. That individual is a sled dog named Balto, who has been immortalized in movies and a statue for helping to bring lifesaving diphtheria antitoxin to Nome, Alaska in an epic journey across the Alaskan wilderness in the winter of 1925. With just a snippet of the dog's preserved skin researchers have made great discoveries.
Published Pulling the plug on viral infections: CRISPR isn't just about cutting
(via sciencedaily.com) Original source CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses. A new study reveals a previously unrecognized player in one such system -- a membrane protein that enhances anti-viral defense. According to study authors, the finding upends the idea that CRISPR systems mount their defense only by degrading RNA and DNA in cells.
Published Information 'deleted' from the human genome may be what made us human
(via sciencedaily.com) Original source What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard. The new findings, published April 28 in the journal Science, fill an important gap in what is known about historical changes to the human genome.
Published Mammalian evolution provides hints for understanding the origins of human disease
(via sciencedaily.com) Original source Even though it is important to know where these variations are located in the genome, it's also useful to know how or why these genetic variations happened in the first place.
Published How dormant bacteria come back to life
(via sciencedaily.com) Original source Bacterial spores can survive for years, even centuries, without nutrients, resisting heat, UV radiation, and antibiotics. How inert, sleeping bacteria -- or spores -- spring back to life has been a century-long mystery. New research identifies how sensor proteins revive dormant bacteria. Discovery opens new routes to combat spore resistance to antibiotics and sterilization. Findings can inform novel strategies to prevent infections, food spoilage.
Published Male California sea lions are becoming bigger and better fighters as their population rebounds
(via sciencedaily.com) Original source California sea lions have managed to maintain -- and, in the case of males, increase -- their average body size as their population grows and competition for food becomes fiercer. This is in contrast to other marine mammals, whose average body size tends to decrease as their numbers increase. Researchers report that sexual selection was a strong driving force for males to grow bigger and to strengthen muscles in their neck and jaw that help them fight for mates. Both male and female sea lions evaded food shortages by diversifying their diets and, in some cases, foraging further from the shore.
Published New findings indicate gene-edited rice might survive in Martian soil
(via sciencedaily.com) Original source New research suggests future Martian botanists may be able to grow gene-edited rice on Mars.
Published Brain circuits for locomotion evolved long before appendages and skeletons
(via sciencedaily.com) Original source Scientists found parallels between the neural circuitry that guides locomotion in sea slugs and in more complex animals like mammals.
Published Robot fish makes splash with motion breakthrough
(via sciencedaily.com) Original source A coil-powered robot fish could make underwater exploration more accessible.
Published Near-universal T cell immunity towards a broad range of bacteria
(via sciencedaily.com) Original source Typically T cells of the immune system respond to a specific feature (antigen) of a microbe, thereby generating protective immunity. Scientists have discovered an exception to this rule. Namely, a group of divergent bacterial pathogens, including pneumococci, all share a small highly conserved protein sequence, which is both presented and recognized by human T cells in a conserved population-wide manner.
Published Ocean ecosystem: Mixotrophic microorganisms play key role
(via sciencedaily.com) Original source Researchers have identified a previously unknown group of bacteria, called UBA868, as key players in the energy cycle of the deep ocean. They are significantly involved in the biogeochemical cycle in the marine layer between 200 and 1000 meters.
Published Jellyfish-like robots could one day clean up the world's oceans
(via sciencedaily.com) Original source Roboticists have developed a jellyfish-inspired underwater robot with which they hope one day to collect waste from the bottom of the ocean. The almost noise-free prototype can trap objects underneath its body without physical contact, thereby enabling safe interactions in delicate environments such as coral reefs. Jellyfish-Bot could become an important tool for environmental remediation.
Published Luring the virus into a trap
(via sciencedaily.com) Original source Viruses like influenza A and Ebola invade human cells in a number of steps. Research teams investigated the final stages of viral penetration using electron tomography and computer simulations. So-called fusion pores, through which the viral genome is released into the host cell, play a central role in these processes. If they can be prevented from forming, the virus is also blocked. The Heidelberg scientists describe previously unknown mechanisms, which might lead to new approaches to prevent infections.
Published Researchers reveal an ancient mechanism for wound repair
(via sciencedaily.com) Original source The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published Whales stop by Gold Coast bay for day spa fix with full body scrubs
(via sciencedaily.com) Original source A new Griffith University study has found that humpback whales will use sandy, shallow bay areas to 'roll' around in sandy substrates to remove dead skin cells on their return journeys south to cooler waters. Using data and footage collected from the tags, whales were observed performing full and side rolls in up to 49m water depth on the sea floor that was lined with fine sand or rubble.
Published Researchers reveal a map to study novel form of cell-to-cell communication
(via sciencedaily.com) Original source An international team of researchers lays the foundation to examine how extracellular RNA and its carrier proteins found in bodily fluids function in a healthy as well as a diseased setting, potentially providing a means to accurately implement early detection and monitor disease processes.
Published Elephant seals drift off to sleep while diving far below the ocean surface
(via sciencedaily.com) Original source For the first time, scientists have recorded brain activity in a free-ranging, wild marine mammal, revealing the sleep habits of elephant seals during the months they spend at sea. The new findings show that while elephant seals may spend 10 hours a day sleeping on the beach during the breeding season, they average just 2 hours of sleep per day when they are at sea on months-long foraging trips. They sleep for about 10 minutes at a time during deep, 30-minute dives, often spiraling downward while fast asleep, and sometimes lying motionless on the seafloor.
Published Reinforcement learning: From board games to protein design
(via sciencedaily.com) Original source An AI strategy proven adept at board games like Chess and Go, reinforcement learning, has now been adapted for a powerful protein design program. The results show that reinforcement learning can do more than master board games. When trained to solve long-standing puzzles in protein science, the software excelled at creating useful molecules. In one experiment, proteins made with the new approach were found to be more effective at generating useful antibodies in mice than were previous methods. If this method is applied to the right research problems, it likely could accelerate progress in a variety of scientific fields.