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Categories: Biology: Genetics, Ecology: Invasive Species
Published Degradation of cell wall key in the spread of antibiotic resistance
(via sciencedaily.com) Original source A study provides new clues in the understanding of how antibiotic resistance spreads. The study shows how an enzyme breaks down the bacteria's protective outer layer, the cell wall, and thus facilitates the transfer of genes for resistance to antibiotics.
Published Researchers thwart resistant bacteria's strategy
(via sciencedaily.com) Original source Bacteria are experts at evolving resistance to antibiotics. One resistance strategy is to cover their cell walls in sticky and gooey biofilm that antibiotics cannot penetrate. A new discovery could put a stop to this strategy.
Published Sixty-million-year-old grape seeds reveal how the death of the dinosaurs may have paved the way for grapes to spread
(via sciencedaily.com) Original source Scientists discovered the oldest fossil grapes in the Western Hemisphere, which help show how after the death of the dinosaurs, grapes spread across the world.
Published Projected loss of brown macroalgae and seagrasses with global environmental change
(via sciencedaily.com) Original source Researchers predict that climate change will drive a substantial redistribution of brown seaweeds and seagrasses at the global scale. The projected changes are alarming due to the fundamental role seaweeds and seagrasses in coastal ecosystems and provide evidence of the pervasive impacts of climate change on marine life.
Published New deep-learning model outperforms Google AI system in predicting peptide structures
(via sciencedaily.com) Original source Researchers have developed a deep-learning model, called PepFlow, that can predict all possible shapes of peptides -- chains of amino acids that are shorter than proteins, but perform similar biological functions. Peptides are known to be highly flexible, taking on a wide range of folding patterns, and are thus involved in many biological processes of interest to researchers in the development of therapeutics.
Published Last surviving woolly mammoths were inbred but not doomed to extinction
(via sciencedaily.com) Original source The last population of woolly mammoths was isolated on Wrangel Island off the coast of Siberia 10,000 years ago, when sea levels rose and cut the mountainous island off from the mainland. A new genomic analysis reveals that the isolated mammoths, who lived on the island for the subsequent 6,000 years, originated from at most 8 individuals but grew to 200--300 individuals within 20 generations. The researchers report that the Wrangel Island mammoths' genomes showed signs of inbreeding and low genetic diversity but not to the extent that it can explain their ultimate (and mysterious) extinction.
Published Invasive ants spread by hitchhiking on everyday vehicles
(via sciencedaily.com) Original source Ants might spread to new locations by stowing away on everyday vehicles. Previously, this was thought to occur mostly on agricultural equipment.
Published A promising weapon against measles
(via sciencedaily.com) Original source What happens when measles virus meets a human cell? The viral machinery unfolds in just the right way to reveal key pieces that let it fuse itself into the host cell membrane.
Published Potent therapy candidate for fatal prion diseases
(via sciencedaily.com) Original source Scientists have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, a streamlined epigenetic editor, paves the way for a new class of genetic approaches to treat certain diseases.
Published New, holistic way to teach synthetic biology
(via sciencedaily.com) Original source Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published Scientists discover genetic 'off switch' in legume plants that limits biological ability to source nutrients
(via sciencedaily.com) Original source A genetic 'off switch' that shuts down the process in which legume plants convert atmospheric nitrogen into nutrients has been identified for the first time by a team of international scientists.
Published Cell division: Before commitment, a very long engagement
(via sciencedaily.com) Original source Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.
Published New tool enables faster, more cost-effective genome editing of traits to improve agriculture sustainability
(via sciencedaily.com) Original source New research had the goal of reducing the time and cost it takes to bring an improved crop to the marketplace to improve agriculture sustainability.
Published Unlocking the world of bacteria
(via sciencedaily.com) Original source Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team has now introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
Published The on-and-off affair in DNA
(via sciencedaily.com) Original source Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.
Published Revealing the dynamic choreography inside multilayer vesicles
(via sciencedaily.com) Original source Our cells and the machinery inside them are engaged in a constant dance. This dance involves some surprisingly complicated choreography within the lipid bilayers that comprise cell membranes and vesicles -- structures that transport waste or food within cells. In a recent paper, researchers shed some light on how these vesicles self-assemble, knowledge that could help scientists design bio-inspired vesicles for drug-delivery or inspire them to create life-like synthetic materials.
Published Frog 'saunas' a lifeline for endangered frog populations
(via sciencedaily.com) Original source New biologist-designed shelters will help endangered frogs survive the devastating impacts of a deadly fungal disease by regulating their body temperature to fight off infections.
Published Zebrafish reveal how bioelectricity shapes muscle development
(via sciencedaily.com) Original source New research describes how nerve cells and muscle cells communicate through electrical signals during development -- a phenomenon known as bioelectricity. The communication, which takes place via specialized channels between cells, is vital for proper development and behavior. The study identifies specific genes that control the process, and pins down what happens when it goes wrong. The finding offers clues to the genetic origins of muscle disorders in humans.
Published Discovery of vast sex differences in cellular activity has major implications for disease treatment
(via sciencedaily.com) Original source The study reveals vast differences in gene activity within the mitochondria of males compared to females. This is the first study to test effects of all 37 genes in the mitochondrial genome -- genes that copepods and humans share. The study found that males demonstrate more activity across all protein-coding mitochondrial genes than females. Although the study looks at tiny marine organisms called copepods, the findings have weighty implications for human medicine.
Published Fuel treatments reduce future wildfire severity
(via sciencedaily.com) Original source There is a common belief that prescribed burning, thinning trees, and clearing underbrush reduce risks of the severity of future fires. But is that true? A new project analyzing 40 studies where wildfire burned into different vegetation treatments, spanning 11 western states. Researchers found overwhelming evidence that in seasonally dry mixed conifer forests in the western U.S., reducing surface and ladder fuels and tree density through thinning, coupled with prescribed burning or pile burning, could reduce future wildfire severity by more than 60% relative to untreated areas.