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Categories: Biology: Genetics, Ecology: Invasive Species
Published Nanocarrier with escape reflex



Protein-based drugs must be transported into cells in a way that prevents their immediate degradation. A new approach is intended to ensure that they remain intact only in certain cells, such as cancer cells. A Japanese research team has introduced a nanocarrier that can 'escape' from endosomes before its cargo is destroyed there. This ability to escape is only triggered within the endosomes of certain tumor cells.
Published Double trouble at chromosome ends



New findings suggest the end-replication problem, an old standby of biology textbooks, is twice as intricate as once thought.
Published Change in gene code may explain how human ancestors lost tails



A genetic change in our ancient ancestors may partly explain why humans don't have tails like monkeys.
Published New disease testing component facilitates lower-cost diagnostics



Biomedical researchers have developed a new, less expensive way to detect nuclease digestion -- one of the critical steps in many nucleic acid sensing applications, such as those used to identify COVID-19 and other infectious diseases.
Published First DNA study of ancient Eastern Arabians reveals malaria adaptation



People living in ancient Eastern Arabia appear to have developed resistance to malaria following the appearance of agriculture in the region around five thousand years ago.
Published Low-Temperature Plasma used to remove E. coli from hydroponically grown crops



In a new study, a team sterilized a hydroponic nutrient solution using low-temperature plasma generated from electricity and the oxygen in the atmosphere. This new sterilization technique may allow farmers to grow crops without the use of chemical pesticides, representing an important advance in agricultural technology for sustainable crop production.
Published New discovery shows how cells defend themselves during stressful situations



A recent study has unveiled an exciting discovery about how our cells defend themselves during stressful situations. The research shows that a tiny modification in the genetic material, called ac4C, acts as a crucial defender, helping cells create protective storage units known as stress granules. These stress granules safeguard important genetic instructions when the cell is facing challenges. The new findings could help shed light on relevant molecular pathways that could be targeted in disease.
Published Scientists use blue-green algae as a surrogate mother for 'meat-like' proteins



Researchers have not only succeeded in using blue-green algae as a surrogate mother for a new protein -- they have even coaxed the microalgae to produce 'meat fiber-like' protein strands. The achievement may be the key to sustainable foods that have both the 'right' texture and require minimal processing.
Published Microbial comics: RNA as a common language, presented in extracellular speech-bubbles



Decoding the conversations between microbes of hypersaline environments reveals deep insights into the origins of complex life.
Published Cutting-edge 'protein lawnmower' created



Scientists have designed the first synthetic protein-based motor which harnesses biological reactions to fuel and propel itself. 'Imagine if a Roomba could be powered only by the dirt it picks up,' says one of the authors of the study. The motor uses the digestive enzyme trypsin to cut the peptides and convert them into the energy it needs to propel itself.
Published Birds and bee lessons as Pacific field trips also solve 'Michener's mystery'



Eight new Pacific bee species and new insights into Fijian bird behaviour on Viti Levu Island have been described in new scientific studies. The research highlights the potential for species discovery, ecological and conservation knowledge and cultural engagement from Asia-Pacific research collaborations.
Published Blindness from some inherited eye diseases may be caused by gut bacteria



Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice.
Published The small intestine adapt its size according to nutrient intake



Resizing of the intestine is a highly conserved strategy employed by a wide range of organisms to cope with fluctuation in nutrient availability. Nevertheless, very little is known about the mechanisms and signals underlying nutrient-mediated gut resizing. New research has identified one of the signaling pathways implicated in this process.
Published Biomolecular condensates -- regulatory hubs for plant iron supply



Iron is a micronutrient for plants. Biologists now show that regulatory proteins for iron uptake behave particularly dynamically in the cell nucleus when the cells are exposed to blue light -- an important signal for plant growth. They found that the initially homogeneously distributed proteins relocated together into 'biomolecular condensates' in the cell nucleus shortly after this exposure.
Published Ribosomes: Molecular wedge assists recycling



Researchers reveal how cells regenerate protein factories at endoplasmic reticulum.
Published Altering the circadian clock adapts barley to short growing seasons



To ensure that plants flower at the right time of year, they possess an internal clock, which enables them to measure the amount of daylight during a day. Biologists now describe that the mutation of a specific gene makes the flowering time of barley almost entirely independent of day length. This mutation can be useful for breeding varieties adapted to altered climatic conditions with relatively mild winters and hot, dry summers.
Published Compound vital for all life likely played a role in life's origin



A chemical compound essential to all living things has been synthesized in a lab in conditions that could have occurred on early Earth, suggesting it played a role at the outset of life.
Published Metabolic diseases may be driven by gut microbiome, loss of ovarian hormones



Mice that received fecal implants from donors that had their ovaries removed gained more fat mass and had greater expression of liver genes associated with inflammation, Type 2 diabetes, fatty liver disease and atherosclerosis. The findings may shed light on the greater incidence of metabolic dysfunction in postmenopausal women.
Published Damage to cell membranes causes cell aging



Researchers have discovered that damage to the cell membrane promotes cellular senescence, or cell aging.
Published Mice surprise: Researchers discover new native species



Australia can lay claim to two new species of native rodent thanks to a new study. The aptly named delicate mouse was previously thought to be a single species spanning a massive stretch of the country from the Pilbara in Western Australia, across parts of the Northern Territory and through Queensland down to the New South Wales border. We now know there are three distinct species.