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Categories: Biology: Genetics, Ecology: Invasive Species

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A new study shows the isolation and sequencing of more than a century-old RNA molecules from a Tasmanian tiger specimen preserved at room temperature in a museum collection. This resulted in the reconstruction of skin and skeletal muscle transcriptomes from an extinct species for the first time. The researchers note that their findings have relevant implications for international efforts to resurrect extinct species, including both the Tasmanian tiger and the woolly mammoth, as well as for studying pandemic RNA viruses.

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Creating physical gaps in the forest canopy give eastern hemlocks more access to resources and help those trees withstand infestation by an invasive insect.

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Scientists are investigating the previously largely unknown biosynthetic pathway that leads to the formation of cardenolides in plants. In a new study, they present two enzymes from the CYP87A family as key enzymes that catalyze the formation of pregnenolone, the precursor for the biosynthesis of plant steroids, in two different plant families. The discovery of such enzymes should help to develop platforms for the cheap and sustainable production of high quality steroid compounds for medical use.

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The research team generated a series of fire susceptibility maps. These show the proportion of Australia experiencing 'high' or 'very high' fire susceptibility increasing from 14.9% now to 15.66% by 2070 -- while fire susceptibility of areas suitable for the plants that koalas depend on is tipped to jump from 39.56% to 44.61% by 2070.

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Tweaks to the mitochondrial genome hold the potential for better hybrid seed production or to introduce seedless fruits.

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• Twenty-year experiment finds that active replanting beats natural recovery for restoring logged tropical forests. • The higher the diversity of replanted tree species, the more quickly canopy area and biomass recovered. • Results emphasize the importance of preserving biodiversity in pristine forests and restoring it in recovering logged forest.

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Researchers have developed a novel genome editing technique known as NICER, which results in significantly fewer off-target mutations than CRISPR/Cas9 editing. The technique uses a different type of enzyme that makes single-stranded 'nicks' in the DNA. Repair of these nicks is more efficient and accurate than repair of double-strand breaks caused by the current CRISPR/Cas9 editing. This technique represents a novel approach for the treatment of genetic diseases caused by heterozygous mutations.

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Researchers have genetically engineered a marine microorganism to break down plastic in salt water. Specifically, the modified organism can break down polyethylene terephthalate (PET), a plastic used in everything from water bottles to clothing that is a significant contributor to microplastic pollution in oceans.

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Researchers have identified a backup mechanism of protein quality control which prevents the toxic effects of protein aggregation in specific tissues when normal methods of molecular monitoring fail. By understanding how different tissues tackle protein build up, this research could accelerate the identification of ways to protect tissues that are vulnerable to protein build up, possibly tackling both disease-associated protein aggregates and also age-dependent aggregates that accelerate the functional decline of tissues.

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To obtain the biggest cherry harvest, trees should be pollinated by both honey bees and mason bees. This new study shows yet another benefit of biodiversity.

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Researchers have successfully demonstrated that hagfish slime proteins can accurately replicate membranes in the human eye. Scientists were able to properly grow retinal cells on hagfish slime proteins and prove that the protein's behavior changes as the membrane mimics stages of aging and disease.

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During a bout of influenza, B cells interact with other immune cells and then take different paths to defend the body. One path is the B cells that differentiate into lung-resident memory B cells, or lung-BRMs, that are critical for pulmonary immunity. These long-lived, non-circulating lung-BRMs migrate to the lungs from draining lymph nodes and reside there permanently as the first layer of defense that can quickly react to produce antibodies in a future infection.

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Some crop pathogens use a clever trick to multiply and spread infection: they hijack the plant's cellular plumbing. In a new study, researchers unveil a class of bacterial proteins that fold into a straw-like shape and insert themselves into the plant cell membrane, allowing the inside of the leaf to become waterlogged. The researchers also figured out a possible way to block the water channel proteins and prevent infection.

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Scientists identify a new and surprising function of a membrane protein on the surface of cancer cells: It supports and stabilizes an important 'co-stimulatory' factor that enhances the activation of T cells, thus improving the immune response against the tumor.

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HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops. These reservoirs have long been thought to be dormant, but two independent groups of researchers report that a subset of these cells spontaneously produce HIV RNA and proteins that may impact patients' HIV-specific immune responses.

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A new article uses environmental DNA (eDNA) metabarcoding to analyze fish and zooplankton communities. The study found that the movement of water between freshwater bodies, or freshwater connectivity, can transport eDNA. This highlights the potential of eDNA to provide a comprehensive view of freshwater biodiversity.

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Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet.

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Researchers have uncovered new genetic insights into Staphylococcus aureus, revealing what makes the bacterium so dangerous when it enters the blood.

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Peppers are a versatile, flavorful, and widely popular crop, used not only as a healthy food source but also for their medicinal properties. Scientists have now sequenced the genomes of key cultivated and wild pepper species, offering unprecedented insights into pepper evolution, domestication, and genetic diversity.

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One of the most invasive species in the world is Solenopsis invicta, a red fire ant species with a painful sting. Native to South America, the ant has established itself across the globe. A group of ant experts confirm that the species has made its way to Sicily -- the ant's first official sighting in Europe. The ants could soon spread all over the continent, the researchers warn, which could cause major environmental, health, and economic problems in Italy and beyond.