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Categories: Biology: General, Biology: Genetics

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As the home of many beloved snack companies, Pennsylvania values its potatoes. Tasty tubers across the state may face the threat of newly identified pathogen strains, though, according to researchers who made the finding and aim to develop management strategies.

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What did people eat on the west coast of Scandinavia 10,000 years ago? A new study of the DNA in a chewing gum shows that deer, trout and hazelnuts were on the diet. It also shows that one of the individuals had severe problems with her teeth.

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Scientists have known about a particular organelle in plant cells for over a century. However, scientists have only now discovered that organelle's key role in aging.

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To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.

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A molecule sourced from funnel web spider venom shows promise as a safe and effective future drug for heart attacks.

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A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.

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A study has found some surprising features in two new species of burrowing scorpions, including a very strangely shaped 'tail tip' and some 'sexy' anatomy features. Terrestrial biologists have taken a closer look at two new species of the mysterious Urodacus genus of burrowing scorpions endemic to Australia -- only to find a big difference in their tails compared to other species.

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Due to the substantial clinical demand for artificial small-diameter vessels (SDVs), numerous commercial products have emerged. However, the majority of existing artificial SDVs lack an endothelial layer, leading to thrombosis. Fabricating artificial SDVs with a consistently uniform endothelial layer and adequate mechanical properties has proven exceptionally challenging. A research team has now induced spontaneous cell assembly and endothelialization through internal pores.

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A new study by physicists and neuroscientists describes how connectivity among neurons comes about through general principles of networking and self-organization, rather than the biological features of an individual organism.

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In humans, male fertility and sperm fitness decline with age, but scientists have made the surprising discovery that this pattern is not consistent in other animals. The team assessed the results of 379 studies which covered a wide range of animals, including mammals, insects, birds, and fish.

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Cold, flu and COVID-19 season brings that now-familiar ritual: swab, wait, look at the result. But what if, instead of taking 15 minutes or more, a test could quickly determine whether you have COVID-19 with a glowing chemical? In a new study, researchers describe a potential COVID-19 test inspired by bioluminescence. Using a molecule found in crustaceans, they have developed a rapid approach that detects SARS-CoV-2 protein comparably to one used in vaccine research.

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Like Indiana Jones, thresher sharks have mastered the art of the whip using their tails. Now, new research provides intricate details showing that vertebrae anatomy might support the mechanics of extreme body bending in thresher sharks, enabling these expert hunters to weaponize their tails. Using micro-CT scanning similar to CAT scans in humans, and two-dimensional shape analysis, results of the study suggest vertebral anatomy and mineralized microstructure meet the demands required for fast swimming and tail-whipping behavior seen in these species.

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Scientists have successfully demonstrated new technologies that can obtain preserved tissue and high-resolution 3D images within minutes of encountering some of the most fragile animals in the deep ocean.

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A promising antibody failed testing. This is good news for developing a broad-spectrum antidote against the world's most dangerous snake venoms.

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Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced supersulfide are unclear. Now, using a strategically engineered yeast mutant with a deficient CARS gene, researchers from Japan have shown that supersulfides control cell longevity by mediating mitochondrial energy metabolism and regulating protein quality.

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New research has precisely dated some of the oldest fossils of complex multicellular life in the world, helping to track a pivotal moment in the history of Earth when the seas began teeming with new lifeforms -- after four billion years of containing only single-celled microbes.

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Identification of genes under recent selection provides insights into the molecular mechanisms of human-related adaptation in Candida pathogens. The study reveals both known and novel genetic variants associated with drug resistance, offering potential targets for improved antifungal therapies.

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To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.

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Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.

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In a new study, researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.