Showing 20 articles starting at article 1
Categories: Biology: Developmental, Biology: Genetics
Published CRISPR-based genome editing in Nile grass rats
(via sciencedaily.com) Original source A team of researchers has discovered a set of methods that enabled the first successful CRISPR-based genome editing in Nile grass rats.
Published Innovative field experiments shed light on biological clocks in nature
(via sciencedaily.com) Original source A new study has used a series of innovative field experiments to show how plants combine circadian clock signals with environmental cues under naturally fluctuating conditions.
Published Revealing DNA behavior in record time
(via sciencedaily.com) Original source Studying how single DNA molecules behave helps us to better understand genetic disorders and design better drugs. Until now however, examining DNA molecules one-by-one was a slow process. Biophysicists have developed a technique that speeds up screening of individual DNA molecules at least a thousand times. With this technology, they can measure millions of DNA molecules within a week instead of years to decades.
Published Creature the size of a dust grain found hiding in California's Mono Lake
(via sciencedaily.com) Original source Mono Lake is a beautiful but harsh environment, its salty and arsenic-laced water home to brine shrimp, alkali flies and little else. Scientists recently discovered an unsuspected resident, however, a microscopic creature -- a choanoflagelatte -- that forms colonies that harbor their own unique bacterial microbiomes. The creature, part of the sister group to all animals, could shed light on the evolution of animals' intimate interactions with bacteria and the rise of multicellular life.
Published T cells manipulate the memory of innate immune cells
(via sciencedaily.com) Original source Research reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of innate immune cells operated independently. This surprising connection opens up new possibilities for the treatment of various diseases. A mouse model shows that no immunosuppressive drugs are needed after an organ transplantation if this interaction between T cells and the innate immunity is temporarily blocked after the transplantation.
Published Gut molecule slows fat burning during fasting
(via sciencedaily.com) Original source In a struggle that probably sounds familiar to dieters everywhere, the less a Caenorhabditis elegans (C. elegans) worm eats, the more slowly it loses fat. Now, scientists have discovered why: a small molecule produced by the worms' intestines during fasting travels to the brain to block a fat-burning signal during this time.
Published Next time you beat a virus, thank your microbial ancestors
(via sciencedaily.com) Original source When you get infected with a virus, some of the first weapons your body deploys to fight it were passed down to us from our microbial ancestors billions of years ago. According to new research, two key elements of our innate immune system came from a group of microbes called Asgard archaea.
Published Life from a drop of rain: New research suggests rainwater helped form the first protocell walls
(via sciencedaily.com) Original source New research shows that rainwater could have helped create a meshy wall around protocells 3.8 billion years ago, a critical step in the transition from tiny beads of RNA to every bacterium, plant, animal, and human that ever lived.
Published Survival tactics: AI-driven insights into chromatin changes for winter dormancy in axillary buds
(via sciencedaily.com) Original source Epigenetics confers a survival advantage in plants to endure harsh weather by inducing bud dormancy. Environmental factors or intrinsic signals trigger the transition between growth and dormancy. Researchers explore the role of chromatin and transcriptional changes in the bud and further analyze data using artificial intelligence models. The findings of this study highlight epigenetic strategies to overcome the effects of short winters during global warming for plant survival.
Published 'DNA scavengers' can stop some antibiotic resistance from spreading
(via sciencedaily.com) Original source For nearly a century, scientists have waged war on antibiotic-resistant microbes. Researchers say they've found a new way to prevent it -- by unleashing 'DNA scavengers' in wastewater treatment plants.
Published Benefits and downside of fasting
(via sciencedaily.com) Original source Researchers identified a signaling pathway in mice that boosts intestinal stem cells' regeneration abilities after fasting. When cancerous mutations occurred during this regenerative period, mice were more likely to develop early-stage intestinal tumors.
Published Self-repairing mitochondria use novel recycling system
(via sciencedaily.com) Original source A newly identified identified cellular mechanism allows mitochondria to recycle localized damage and maintain healthy function.
Published Surprising mechanism for removing dead cells identified
(via sciencedaily.com) Original source A tandem signaling process turns ordinary cells into an efficient cleanup crew.
Published Compound in rosemary extract can reduce cocaine sensitivity
(via sciencedaily.com) Original source A team of researchers has discovered that an antioxidant found in rosemary extract can reduce volitional intakes of cocaine by moderating the brain's reward response, offering a new therapeutic target for treating addiction.
Published New worm study paves way for better RNA-based drugs to treat human disease
(via sciencedaily.com) Original source Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers.
Published Adaptive 3D printing system to pick and place bugs and other organisms
(via sciencedaily.com) Original source A new adaptive 3D printing system can identify the positions of randomly distributed organisms and safely move them to specific locations for assembly.
Published Scientists discover new code governing gene activity
(via sciencedaily.com) Original source A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists' understanding of gene regulation and how genetic variations may influence gene expression in development or disease.
Published Researchers uncover the secrets of 'plant puberty'
(via sciencedaily.com) Original source Researchers have identified the genetic changes linked to why plants go through a developmental change similar to 'puberty' at different rates, a discovery which could lead to better crop nutrition.
Published Key biofuel-producing microalga believed to be a single species is actually three
(via sciencedaily.com) Original source When a global pandemic forced previous a graduate student out of the lab and onto the computer, he found a world of difference hidden in the long-studied species of Botryoccocus braunii -- and discovered that it isn't one species at all, but three.
Published New insights on how bird flu crosses the species barrier
(via sciencedaily.com) Original source The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's polymerase when it interacts with a human protein essential for the virus to replicate within the cell. The structure of this replication complex provides important information about the mutations that avian influenza polymerase must undergo to adapt to mammals, including humans. These results can help scientists monitor the evolution and adaptability of bird flu strains, such as H5N1 or H7N9, towards infecting other species.