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Categories: Biology: Genetics, Biology: Zoology
Published Novel genome editing approach restores hearing in adult preclinical models with genetic deafness
(via sciencedaily.com) Original source Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing approach. Since mouse and human microRNAs have identical sequences, the researchers hope this work can one day be translated into applications for humans.
Published Pumpkin disease not evolving, could make a difference for management
(via sciencedaily.com) Original source The pathogen that causes bacterial spot is very good at what it does. Forming small lesions on the rinds of pumpkins, melons, cucumbers, and other cucurbits, it mars the fruits' appearance and ushers in secondary pathogens that lead to rot and severe yield loss. The bacterium, Xanthomonas cucurbitae, is so successful that it has had no reason to evolve through time or space.
Published Atlas of proteins reveals inner workings of cells
(via sciencedaily.com) Original source Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.
Published Not so simple: Mosses and ferns offer new hope for crop protection
(via sciencedaily.com) Original source Mosses, liverworts, ferns and algae may offer an exciting new research frontier in the global challenge of protecting crops from the threat of disease.
Published Phage-derived enzyme targets E. faecalis biofilms to mitigate acute graft-versus-host disease
(via sciencedaily.com) Original source Acute graft-versus-host disease occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). Researchers recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.
Published Big gain in battle against harmful bacteria
(via sciencedaily.com) Original source An unexpected find has enabled important progress to be made in the battle against harmful bacteria.
Published Researchers listen to the hearts of bats in flight
(via sciencedaily.com) Original source Unique recordings show that bats can ramp up heart rate from 6 to 900 b.p.m within minutes.
Published New one-step method to make multiple edits to a cell's genome
(via sciencedaily.com) Original source A team of scientists have developed a new method that enables them to make precise edits in multiple locations within a cell -- all at once. Using molecules called retrons, they created a tool that can efficiently modify DNA in bacteria, yeast, and human cells.
Published Global database reveals large gaps in our knowledge of four-footed animals
(via sciencedaily.com) Original source Researchers developed TetrapodTraits -- a global database of animals with four feet -- which can now be applied for better ecology, evolution and conservation research.
Published Groundbreaking study reveals oceanic seabirds chase tropical cyclones
(via sciencedaily.com) Original source A new study reveals that the rare Desertas Petrels (Pterodroma deserta), a wide-ranging seabird in the North Atlantic, exhibit unique foraging behaviors during hurricane season. Contrary to other pelagic seabirds, these petrels do not avoid intense tropical cyclones but instead exploit the dynamic conditions for their benefit, providing new insights into the impact of cyclones on open ocean marine life.
Published Cracking open a tasty menu for captive marsupials to sink their teeth into
(via sciencedaily.com) Original source From sifting through topsoil for native truffles to cracking open hard shells of seeds and nuts to munch on the tasty kernels, Australia bettongs and potoroos are described as 'ecosystem engineers' in a two-way relationship between their rich diet and environmental health. However, with native ecosystems and potoroid marsupial numbers in decline, ecology and evolution experts are working to understand how difficult it is to bite into the foods these leading foragers seek out.
Published Life underground suited newly discovered dinosaur fine
(via sciencedaily.com) Original source A newly discovered ancestor of Thescelosaurus shows evidence that these animals spent at least part of their time in underground burrows. The new species contributes to a fuller understanding of life during the mid-Cretaceous -- both above and below ground.
Published Study projects major changes in North Atlantic and Arctic marine ecosystems due to climate change
(via sciencedaily.com) Original source New research predicts significant shifts in marine fish communities in the North Atlantic and Arctic Oceans as a result of climate warming.
Published Scientists discover how to improve vaccine responses to potentially deadly bacterium
(via sciencedaily.com) Original source Researchers have taken a leap forward in understanding how we might fight back against the potentially deadly MRSA bacterium. They have shown in an animal model that targeting a key suppressive immune molecule (IL-10) during the delivery of a vaccine improves the ability of the vaccine to protect against infection.
Published Restored oyster sanctuaries host more marine life
(via sciencedaily.com) Original source Oysters sanctuaries in Chesapeake Bay are working for more than just oysters. Compared to nearby harvest areas, sanctuaries contain more abundant populations of oysters and other animal life--and the presence of two common parasites isn't preventing that.
Published New bio-based tool quickly detects concerning coronavirus variants
(via sciencedaily.com) Original source Researchers have developed a bioelectric device that can detect and classify new variants of coronavirus to identify those that are most harmful. It has the potential to do the same with other viruses, as well.
Published Genomic data integration improves prediction accuracy of apple fruit traits
(via sciencedaily.com) Original source Genotyping techniques can be used to select fruit trees with desired traits at the seedling stage, increasing the efficiency of fruit tree breeding. However, so far, there are multiple different genotyping systems, each generating distinct datasets. In a recent study, Japanese scientists revealed that integrating genomic data obtained with different genotyping systems can effectively combine with historical data, leveraging the accuracy of genomic predictions.
Published Brain size riddle solved as humans exceed evolution trend
(via sciencedaily.com) Original source The largest animals do not have proportionally bigger brains -- with humans bucking this trend -- a new study has revealed.
Published GeneMAP discovery platform will help define functions for 'orphan' metabolic proteins
(via sciencedaily.com) Original source Researchers have developed a discovery platform to probe the function of genes involved in metabolism -- the sum of all life-sustaining chemical reactions. The investigators used the new platform, called GeneMAP (Gene-Metabolite Association Prediction), to identify a gene necessary for mitochondrial choline transport.
Published Migrating starlings are no copycats
(via sciencedaily.com) Original source Young, na ve starlings are looking for their wintering grounds independently of experienced conspecifics. Starlings are highly social birds throughout the year, but this does not mean that they copy the migration route from each other. By revisiting a classic 'displacement' experiment and by adding new data, a team of researchers have settled a long-lasting debate.