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Categories: Biology: Genetics, Biology: Zoology
Published Cracking the code of life: new AI model learns DNA's hidden language
(via sciencedaily.com) Original source With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its rules and context to draw functional information about the DNA sequences.
Published Why virus causing cold sores does not spread to devastating brain infection
(via sciencedaily.com) Original source A previously unknown defence mechanism in the brain prevents herpesvirus from infecting the brain's nerve cells.
Published Discovery of a new population of macrophages promoting lung repair after viral infections
(via sciencedaily.com) Original source Researchers have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses. These macrophages are instrumental in repairing the pulmonary alveoli. This groundbreaking discovery promises to revolutionize our understanding of the post-infectious immune response and opens the door to new regenerative therapies.
Published Reduction in folate intake linked to healthier aging in animal models
(via sciencedaily.com) Original source Scientists found that decreasing folate intake can support healthier metabolisms in aging animal models, challenging the conventional belief that high folate consumption universally benefits health.
Published Coinfecting viruses impede each other's ability to enter cells
(via sciencedaily.com) Original source The process by which phages -- viruses that infect and replicate within bacteria -- enter cells has been studied for over 50 years. In a new study, researchers have used cutting-edge techniques to look at this process at the level of a single cell.
Published New research sheds light on relationships between plants and insects in forest ecosystems
(via sciencedaily.com) Original source Researchers have published new findings on how leaf-eating insects affect forest ecosystems worldwide. Researchers are aware of how large herbivores cycle nutrients in forests. They know much less, however, about how leaf-eating insects impact forest carbon and nutrient cycling.
Published Fossil shows how penguins' wings evolved
(via sciencedaily.com) Original source A tiny fossil penguin plays a huge role in the evolutionary history of the bird, an international study shows.
Published Circular RNAs: The new frontier in cancer research
(via sciencedaily.com) Original source Unravelling the complexities of circular RNAs (circRNAs) in cancer biology has positioned scientists on the cusp of revolutionary breakthroughs in the diagnosis and treatment of cancer. A new study predicts remarkable potential for circular RNAs to improve cancer treatment and patient outcomes within the next 5-10 years.
Published Flamingos don't preen more than other waterbirds
(via sciencedaily.com) Original source Despite their famously fancy feathers, flamingos don't spent more time preening than other waterbirds, new research shows.
Published What gave the first molecules their stability?
(via sciencedaily.com) Original source The origins of life remain a major mystery. How were complex molecules able to form and remain intact for prolonged periods without disintegrating? A team has demonstrated a mechanism that could have enabled the first RNA molecules to stabilize in the primordial soup. When two RNA strands combine, their stability and lifespan increase significantly.
Published Genetic signatures of domestication identified in pigs, chickens
(via sciencedaily.com) Original source Wild boars and red junglefowl gave rise to common pigs and chickens. These animals' genes evolved to express themselves differently, leading to signatures of domestication -- such as weaker bones and better viral resistance -- in pigs and chickens, according to a research team.
Published When it comes to DNA replication, humans and baker's yeast are more alike than different
(via sciencedaily.com) Original source Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to keep parts of the replication machinery from falling off the DNA strand.
Published Half a billion-year-old spiny slug reveals the origins of mollusks
(via sciencedaily.com) Original source Exceptional fossils with preserved soft parts reveal that the earliest mollusks were flat, armored slugs without shells. The new species, Shishania aculeata, was covered with hollow, organic, cone-shaped spines. The fossils preserve exceptionally rare detailed features which reveal that these spines were produced using a sophisticated secretion system that is shared with annelids (earthworms and relatives).
Published Climate change may lead to shifts in vital Pacific Arctic fisheries
(via sciencedaily.com) Original source Commercially important marine fish and invertebrate species will likely shift northwards under a warmer climate, according to new research.
Published Novel nanosensing technique for quality control of viral vectors in gene therapy
(via sciencedaily.com) Original source Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can differentiate between functional and faulty viral vectors at the single-particle level. This convenient and inexpensive technique will hopefully get us one step closer to advancing treatments for genetic disorders.
Published Talking about regeneration
(via sciencedaily.com) Original source Researchers transferred genes from simple organisms capable of regenerating their bodies into common fruit flies, more complex animals that cannot. They found the transferred gene suppressed an age-related intestinal issue in the flies. Their results suggest studying genes specific to animals with high regenerative capability may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.
Published Study examines effect of fish oil in older adults' brains
(via sciencedaily.com) Original source A clinical trial suggests that a subset of older adults with a genetic predisposition to Alzheimer's disease may benefit from fish oil supplements.
Published Mass extinction 66 million years ago triggered rapid evolution of bird genomes
(via sciencedaily.com) Original source Study finds that the mass extinction caused by an asteroid about 66 million years ago led to critical changes in bird genomes that ultimately sparked the incredibly diversity living birds.
Published The next generation of RNA chips
(via sciencedaily.com) Original source An international research team has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient.
Published Scientists devise method to secure Earth's biodiversity on the moon
(via sciencedaily.com) Original source New research led proposes a plan to safeguard Earth's imperiled biodiversity by cryogenically preserving biological material on the moon. The moon's permanently shadowed craters are cold enough for cryogenic preservation without the need for electricity or liquid nitrogen.