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Categories: Biology: Genetics, Space: Astrophysics
Published Searching old stem cells that stay young forever



The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes.
Published Preliminary study shows potential of Manuka honey as a nutraceutical for breast cancer



A new study found that Manuka honey could potentially be an alternative, natural option for breast cancer prevention and treatment -- particularly for estrogen receptor (ER)-positive breast cancer, the most common subtype of breast cancer that accounts for about 70-80% of all breast cancer cases.
Published Right on schedule: Physicists use modeling to forecast a black hole's feeding patterns with precision



The dramatic dimming of a light source ~ 870 million light years away from Earth confirms the accuracy of a detailed model.
Published Probiotics during pregnancy shown to help moms and babies



Giving probiotics to pregnant mice can enhance both the immune system and behavior of the mothers and their offspring.
Published Zebrafish use surprising strategy to regrow spinal cord



A new study maps out a detailed atlas of all the cells involved in regenerating the zebrafish spinal cord. In an unexpected finding, the researchers showed that survival and adaptability of the severed neurons themselves is required for full spinal cord regeneration. Surprisingly, the study showed that stem cells capable of forming new neurons play a complementary role but don t lead the process.
Published Surprise finding in study of environmental bacteria could advance search for better antibiotics



Researchers studying bacteria from freshwater lakes and soil say they have determined a protein's essential role in maintaining the germ's shape. Because the integrity of a bacterial cell's 'envelope' or enclosure is key to its survival, the finding could advance the search for new and better antibiotics.
Published Galaxies in dense environments tend to be larger, settling one cosmic question and raising others



A new study has found galaxies with more neighbors tend to be larger than their counterparts that have a similar shape and mass, but reside in less dense environments. The team, which used a machine-learning algorithm to analyze millions of galaxies, reports that galaxies found in denser regions of the universe are as much as 25% larger than isolated galaxies. The findings resolve a long-standing debate among astrophysicists over the relationship between a galaxy's size and its environment, but also raise new questions about how galaxies form and evolve over billions of years.
Published Revealing the mysteries within microbial genomes



A new technique will make it much easier for researchers to discover the traits or activities encoded by genes of unknown function in microbes, a key step toward understanding the roles and impact of individual species within the planet's diverse microbiomes.
Published How bread dough gave rise to civilization



A major international study has explained how bread wheat helped to transform the ancient world on its path to becoming the iconic crop that today helps sustain a global population of eight billion.
Published Beige fat cells with a 'Sisyphus mechanism'



A new class of fat cells makes people healthier. The cells consume energy and produce heat through seemingly pointless biochemical reactions.
Published A ketogenic diet could improve the response to pancreatic cancer therapy



Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer therapy.
Published Decoding the world's largest animal genome



Scientists have sequenced the largest genome of all animals, the lungfish genome. Their data help to explain how the fish-ancestors of today's land vertebrates were able to conquer land.
Published Researchers call for genetically diverse models to drive innovation in drug discovery



Researchers unveiled an approach to drug discovery that could revolutionize how we understand and treat diseases. Their commentary explains the limitations of studies using traditional mouse models and proposes using genetically diverse mice and mouse and human cells to better predict human responses to drugs and diseases.
Published Exciting advance in stem cell therapy



A new technique for mechanically manipulating stem cells could lead to new stem cell treatments, which have yet to fulfill their therapeutic potential.
Published Surprising insight into cancer comes from unique plant species that find different solutions to evolutionary challenges



A study has shown that different plant species tackle the same evolutionary hurdle in different ways, and the findings may give insight into aggressive forms of cancer.
Published Rewriting the evolutionary history of critical components of the nervous system



A new study has rewritten the conventionally understood evolutionary history of certain ion channels -- proteins critical for electrical signaling in the nervous system. The study shows that the Shaker family of ion channels were present in microscopic single cell organisms well before the common ancestor of all animals and thus before the origin of the nervous system.
Published Starvation and adhesion drive formation of keratinocyte patterns in skin



Cell-cell adhesion-induced patterning in keratinocytes can be explained by just starvation and strong adhesion researchers find.
Published Study reveals oleoyl-ACP-hydrolase underpins lethal respiratory viral disease



Respiratory infections can be severe, even deadly, in some individuals, but not in others. Scientists have gained new understanding of why this is the case by uncovering an early molecular driver that underpins fatal disease. Oleoyl-ACP-hydrolase (OLAH) is an enzyme involved in fatty acid metabolism. A study shows that OLAH drives severe disease outcomes.
Published Researchers ID body's 'quality control' regulator for protein folding



Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease. Fortunately, our bodies have a quality-control system that identifies misfolded proteins and marks them either for additional folding work or destruction, but how, exactly, this quality-control process functions is not entirely known. Researchers have now made a major leap forward in our understanding of how this quality-control system works by discovering the 'hot spot' where all the action takes place.
Published How mortal filaments' self-assemble and maintain order: Align or die



A previously unknown mechanism of active matter self-organization essential for bacterial cell division follows the motto 'dying to align': Misaligned filaments 'die' spontaneously to form a ring structure at the center of the dividing cell. The work could find applications in developing synthetic self-healing materials.