Showing 20 articles starting at article 1061
< Previous 20 articles Next 20 articles >
Categories: Biology: Genetics, Environmental: Ecosystems
Published Genomic tug of war could boost cancer therapy
(via sciencedaily.com) Original source Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic syndromes that is plagued by drug resistance issues. For the first time, researchers show that decitabine causes coding and non-coding regions of DNA to engage in a tug of war for a gene activator, called H2A.Z. Typically, deticabine draws this gene activator away from coding DNA, causing gene expression to grind to a halt and cells to die. However, many types of cancer have very high levels of H2A.Z, which may help them overcome this decitabine-induced tug of war, allowing the cancer to grow.
Published How cell identity is preserved when cells divide
(via sciencedaily.com) Original source A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation. Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.
Published Much more than waste: Tiny vesicles exchange genetic information between cells in the sea
(via sciencedaily.com) Original source Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea.
Published New global stocktake: Healthy forests could store much more carbon
(via sciencedaily.com) Original source Natural carbon reservoirs will play a major role at the COP28 world climate conference in the United Arab Emirates. In a recent study, a team of more than two hundred researchers worldwide presents new estimates of the storage potential of forests around the globe. According to the study, forests could ideally absorb 328 billion tons (gigatons, Gt for short) of carbon. However, as many formerly forested areas are now used for agriculture and as settlement areas, the potential is reduced to 226 Gt. 139 Gt of this (61%) could be achieved by protecting existing forests alone. The remaining 87 Gt (39%) could be realized by reconnecting previously fragmented forest landscapes and managing them sustainably.
Published Bear genes show circadian rhythms even during hibernation
(via sciencedaily.com) Original source The internal clocks of grizzly bears appear to keep ticking through hibernation, according to a genetic study. This persistence highlights the strong role of circadian rhythms in the metabolism of many organisms including humans. The genetic study confirmed observational evidence that bears' energy production still waxes and wanes in a daily pattern even as they slumber for several months without eating. The researchers also found that during hibernation the amplitude of the energy production was blunted, meaning the range of highs and lows was reduced. The peak also occurred later in the day under hibernation than during the active season, but the daily fluctuation was still there.
Published Hormones have the potential to treat liver fibrosis
(via sciencedaily.com) Original source Researchers have discovered previously unknown changes in a specific type of liver cells, potentially opening avenues for a new treatment for liver fibrosis, a potentially life-threatening condition. Currently, there are no drugs available to treat liver fibrosis.
Published Climate change effects hit marine ecosystems in multiple waves, according to marine ecologists
(via sciencedaily.com) Original source A new approach to examining the effects of climate change on marine ecosystems may provide a more accurate understanding of climate change responses -- and predictions for future consequences -- according to a new article. The paper highlights the interplay between the trend of climate warming and the fluctuations in local temperature. These two properties cause atypically warm events such as marine heatwaves to occur with increasing frequency and magnitude.
Published How bacteria recognize viral invasion and activate immune defenses
(via sciencedaily.com) Original source Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.
Published Clearing mangroves makes 'muddification' worse
(via sciencedaily.com) Original source Clearing mangroves to stop estuaries getting clogged with mud actually makes the problem worse, new research shows.
Published New scientific study reveals the crucial role of herbivorous fishes and sea urchins in restoring Caribbean coral reefs
(via sciencedaily.com) Original source A new study presents crucial findings on the feeding preferences of herbivorous fishes and the sea urchin Diadema antillarum in Little Cayman. The study sheds new light on the dynamics of these herbivores and their impact on the resilience of Caribbean coral reefs.
Published Surveilling wetlands for infectious bird flu -- and finding it
(via sciencedaily.com) Original source Recently, morning omelets and holiday dinners have gotten more expensive. One likely cause is bird flu, outbreaks of which led to the deaths of millions of chickens and turkeys from infection or culling in 2022, according to the U.S. Department of Agriculture, and which still demands rigorous monitoring of wild populations. Now, researchers have developed a method that detected infectious bird flu virus in wetlands frequented by waterfowl.
Published Colliding ribosomes activate RNA repair
(via sciencedaily.com) Original source Researchers discover how ribosomes contribute to the recognition and removal of RNA crosslinking damage.
Published Unexpected discovery opens bioengineering opportunities for human and plant health
(via sciencedaily.com) Original source An unexpected genetic discovery in wheat has led to opportunities for metabolic engineering of versatile compounds with potential to improve its nutritional qualities and resilience to disease.
Published Genetic discovery promises high-iron vegetables and cereals
(via sciencedaily.com) Original source A genetic breakthrough has opened new opportunities for iron-fortified vegetables and cereal crops to help address the global health issue of anemia.
Published Novel C. diff structures are required for infection, offer new therapeutic targets
(via sciencedaily.com) Original source Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles.
Published Previously unknown luminescence revealed in ten deep sea species and an order of sea cucumbers
(via sciencedaily.com) Original source Researchers present evidence of previously unknown luminosity in 10 deep-sea species, suggesting underestimated diversity. These new discoveries include a member of the order Molpadia, which was previously thought not to be luminescent. The authors stress the importance of considering the ecological role of bioluminesence and the need for conservation.
Published Non-native species likely to continue spreading in North America, Australia and Europe
(via sciencedaily.com) Original source Naturalized species, which are not native but have established themselves in new locations, have the potential to spread even further to suitable habitats in many parts of the world, reports a new study.
Published Forecasting microbiomes for sustainability and health
(via sciencedaily.com) Original source Microbial communities, or microbiomes, are essential for safeguarding human and environmental health through the most widely used biotechnological process on our planet: biological wastewater treatment. However, the process itself is subject to constant changes, difficult to sustain over long periods of time and emits significant amounts of greenhouse gases.
Published Europe was not covered by dense forest before the arrival of modern humans
(via sciencedaily.com) Original source For decades, we believed that outside ice ages Europe was mostly covered by dense forest before the arrival of modern humans. Now, a new study shows that there was far more open and semi-open vegetation than conventionally expected.
Published A tale of two proteins: Fundamental research could make growing better crops like clockwork
(via sciencedaily.com) Original source Rhomboid-like protein 10, or RBL10, is thought to be an enzyme that degrades other proteins in the chloroplast membrane, but its function is largely unknown. Researchers are studying how RBL10 affects photosynthetic membrane lipid metabolism, an essential process in photosynthesis.