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Categories: Biology: Genetics, Environmental: Biodiversity

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By adding synergistic self-adjuvanting properties to COVID-19 RNA vaccines, researchers showed they could significantly boost the immune response generated in mice.

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Genetic manipulation of a puzzling, miniscule bacteria that has lived in human mouths at least since the Middle Stone Age is elucidating the genes needed for its unusual lifestyle. These Patescibacteria in the human oral microbiome reside on the surface of another, larger host microbe. Found in many water and land environments, Patescibacteria in general lack the genes required to make many molecules necessary for life, such as the amino acids that make up proteins, the fatty acids that form membranes, and the nucleotides in DNA. This has led researchers to speculate that many of them rely on other bacteria to grow. In a new study, researchers present the first glimpse into the molecular mechanisms behind their relationship with their host cells. They also share details gleaned from fluorescent, time-lapse microsopic imaging of these bacteria as they bud and send out swarms of tiny progeny, only a fraction of which are able to establish a host relationship.

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When dairy cows are fed diets with reduced protein concentrations -- aimed at decreased environmental nitrogen pollution from their manure such as nitrate leaching, nutrient-laden run-off and ammonia volatilization -- their milk production can suffer. Supplementing the amino acid histidine may help in maintaining, and even increasing, milk and milk-protein yields.

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Herpes is not only unpleasant but it can, in some cases, also have dangerous complications and life-threatening consequences. A research team has now introduced a completely new approach for treating herpes. Their method is based on the inhibition of an enzyme that is needed for the release of newly formed virus particles from infected cells.

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Scientists have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring. The findings shed new light on genomic imprinting, a fundamental, biological process in which a gene from one parent is switched off while the copy from the other parent remains active. Errors in imprinting are linked to a host of diseases, such as the rare disease Silver-Russell syndrome along with certain cancers and diabetes.

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As the climate and wildfire crises have intensified, so too have concerns regarding the loss of carbon captured and stored in forests from decades to centuries of tree growth. A new study describes where to optimize ongoing wildfire mitigation efforts and reduce carbon loss due to wildfire, benefitting communities and climate at the same time. The study evaluated where living trees and the carbon they store are at risk of burning in the future. They then compared these areas to communities that are vulnerable to wildfire as identified in the Forest Service's Wildfire Crisis Strategy. Areas of overlap highlight 'opportunity hot spots' where action can reduce the risk from wildfire to both carbon and communities.

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Researchers have investigated how the behavior of an individual wheat plant under limiting light conditions influences the performance of the whole community. They assessed morphological and biomass phenotypes of single plants grown in mixtures under sunlight and a simulated canopy shade, and the relevance of these phenotypes for the monoculture community in the field.

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A team of researchers has revealed that the Dumpy protein, a component of extracellular matrices -- or ECM -- is the key factor in regulating the stereotypic origami-like folding of wing-cell sheets. Their findings that wing cells never divide during folding nor do they exhibit spatially distinct behaviors suggest how external cues can create consistent 3D tissue structures.

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Mold and diseases caused by fungi can greatly impact the shelf life of fruit and vegetables. However, some fungi benefit their hosts by aiding plant survival. Colletotrichum tofieldiae (Ct) is a root mold which typically supports continued plant development even when the plant is starved of phosphorus, an important nutrient for photosynthesis and growth. Researchers studied a unique pathogenic strain of the fungi, called Ct3, which conversely inhibits plant growth.

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Neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmosets to accelerate the pace of drug discovery and rebuild the foundation for future translational studies.

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Scientists identify ways landowners in rural Brazil can find win-win situations with biodiversity and farming.

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Invasive alien species are animals that may pose a threat to biodiversity, but it's time to deal with that threat in a more ethical way.

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In just 26 years, the distribution of rare butterflies has plummeted by 72% in Eastern Denmark. Several species are threatened with extinction, yet the conservation actions aiming to safeguard species have proved unsuccessful.

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Important progress for RNA research: A team has discovered a new ribozyme that can label RNA molecules in living cells.

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A new study has shown that a subtype of avian flu virus, endemic in poultry farms in China, is undergoing mutational changes, which could increase the risk of the disease being passed on to humans.

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Elephants, buffaloes and other heavy herbivores are effective against invasive plants. This is the conclusion of a new study that used Indian data, including data from the world's largest survey of wildlife based on camera traps. But smaller animals can do the same: you don't need elephants to get the same effect, the researchers point out.

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Diversified farming is an important complement to forest protections for reversing tropical biodiversity declines.

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More than 100 years of observations in nature have revealed a universal pattern of species abundances: Most species are rare but not very rare, and only a few species are very common. These so-called global species abundance distributions have become fully unveiled for some well-monitored species groups, such as birds. For other species groups, such as insects, however, the veil remains partially unlifted. A new study demonstrates how important biodiversity monitoring is for detecting species abundances on planet Earth and for understanding how they change.

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When fighting disease, our immune cells need to reach their target quickly. Researchers have now discovered that immune cells actively generate their own guidance system to navigate through complex environments. This challenges earlier notions about these movements. The researchers' findings enhance our knowledge of the immune system and offer potential new approaches to improve human immune response.

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Researchers have determined how Leishmaniasis vaccine candidates, created using mutated disease-causing parasites, prompt molecular-level changes in host cells that have specific roles in helping generate the immune response.