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Categories: Biology: Genetics, Environmental: Biodiversity
Published Artificial streams reveal how drought shapes California's alpine ecosystems



Researchers have used a series of artificial stream channels to mimic the behavior of headwater creeks under future climate change scenarios. They found that drier conditions shifted the life cycles of the algae and insects that form the base of the alpine food web. However, because species adjusted to the shifts in a variety of ways, the stream ecosystems were generally resilient to the changing conditions.
Published Eyes open and toes out of water: How a giant water bug reached the island of Cyprus



A new visitor was reported on the coast of Cyprus, thanks to the growing power of citizen science. Researchers collected information and specimens through personal communication with amateur naturalists, but also through the internet, in order to compose the mosaic of repeated appearances of a giant water bug on the eastern shoreline of the island.
Published Engineers measure pH in cell condensates



In a first for the condensate field, researchers have figured out how nucleolar sub-structures are assembled. This organization gives rise to unique pH profiles within nucleoli, which they measured and compared with the pH of nearby non-nucleolar condensates including nuclear speckles and Cajal bodies.
Published The atlas of unburnable oil in the world



In order to limit the increase in global average temperature to 1.5 C, it is essential to drastically reduce carbon dioxide emissions in the atmosphere. This would mean not exploiting most of the existing coal, conventional gas and oil energy resources in regions around the world, according to new research. The study presents the atlas of unburnable oil in the world, a world map designed with environmental and social criteria that warns which oil resources should not be exploited to meet the commitments of the Paris Agreement signed in 2015 to mitigate the effects of climate change.
Published Machine learning classifier accelerates the development of cellular immunotherapies



Making a personalized T cell therapy for cancer patients currently takes at least six months. Scientists have shown that the laborious first step of identifying tumor-reactive T cell receptors for patients can be replaced with a machine learning classifier that halves this time.
Published Protein fragments ID two new 'extremophile' microbes--and may help find alien life



Perfectly adapted microorganisms live in extreme environments from deep-sea trenches to mountaintops. Learning more about how these extremophiles survive in hostile conditions could inform scientists about life on Earth and potential life on other planets.
Published It's hearty, it's meaty, it's mold



Scientists are exploring how tuning the genomes of mushrooms and molds can transform these food sources into gourmet, nutrient-packed meals made with minimal processing and a light environmental footprint.
Published New bioengineered protein design shows promise in fighting COVID-19



A recent scientific breakthrough has emerged from the work of researchers aiming to combat SARS-CoV-2, the virus responsible for COVID-19. The study focuses on the design and development of a novel protein capable of binding to the spike proteins found on the surface of the coronavirus. The goal behind this innovative approach is twofold: first, to identify and recognize the virus for diagnostic purposes, and second, to hinder its ability to infect human cells.
Published New discovery reveals how the egg controls sperm entry



After the egg has been fertilized by a sperm, the surrounding egg coat tightens, mechanically preventing the entry of additional sperm and the ensuing death of the embryo, a new study finds. The work also explains how mutations in egg coat proteins can cause female infertility and may eventually lead to new contraceptive methods.
Published Even cells know the importance of recycling



Researchers uncovered the mechanistic details behind how several proteins interact to help cells recognize and remove damaged mitochondria. Optineurin (OPTN) and its interactions are needed to provide a contact site for another protein, Tank-binding kinase 1 (TBK1), during this process. The OPTN-TBK1 relationship is necessary for these mitochondria to be recognized and eliminated from the cell. This mechanism may have relevance for developing drugs to treat Parkinson's disease.
Published Sulfur and the origin of life



A new study shines a spotlight on sulfur, a chemical element that, while all familiar, has proved surprisingly resistant to scientific efforts in probing its role in the origin of life.
Published Tryptophan in diet, gut bacteria protect against E. coli infection



Gut bacteria and a diet rich in the amino acid tryptophan can play a protective role against pathogenic E. coli, which can cause severe stomach upset, cramps, fever, intestinal bleeding and renal failure.
Published New computational strategy boosts the ability of drug designers to target proteins inside the membrane



Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new custom-designed proteins that can efficiently reach these 'intramembrane' targets.
Published Simple trick could improve accuracy of plant genetics research



Researchers have published a simple trick that improves the accuracy of techniques that help us understand how external variables -- such as temperature -- affect gene activity in plants.
Published Milk to the rescue for diabetics? Cow produces human insulin in milk



An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk. The advancement could herald a new era in insulin production, one day eliminating drug scarcity and high costs for people living with diabetes.
Published A simple and robust experimental process for protein engineering



A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study.
Published Exploring arctic plants and lichens: An important conservation baseline for Nunavut's newest and largest territorial park



A comprehensive study of the floristic diversity of Agguttinni Territorial Park, Nunavut's newest and largest Territorial Park, has documented 141 vascular plant, 69 bryophyte, and 93 lichen species from this unique protected area on northern Baffin Island. Through a combination of extensive fieldwork in 2021 and examination of hundreds of existing herbarium specimens, the authors have documented species newly reported for Baffin Island and have crafted a biodiversity baseline important for park management and conservation.
Published Scientists find weak points on Epstein-Barr virus



Studies of interactions between two lab-generated monoclonal antibodies (mAbs) and an essential Epstein-Barr virus (EBV) protein have uncovered targets that could be exploited in designing treatments and vaccines for this extremely common virus.
Published How a natural compound from sea squirts combats cancer



Trabectedin, a promising drug derived from the sea squirt Ecteinascidia turbinata, has shown potential in combating cancers resistant to conventional treatments. However, its precise mechanism of action has remained elusive -- until now.
Published Rice paddy snake diversification was driven by geological and environmental factors in Thailand, molecular data suggests



A new study of rice paddy snakes in Southeast Asia gives key details to their diversification and natural history, adding molecular evidence that the rise of the Khorat Plateau and subsequent environmental shifts in Thailand may have altered the course of the snakes' evolution some 2.5 million years ago.