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Categories: Biology: Genetics, Environmental: Biodiversity
Published Climate change threatens older elephants most, jeopardizing African elephants' future
(via sciencedaily.com) Original source A collaborative team of researchers has conducted first-of-its kind research into how global climate change affects African elephants. The work shows that older elephants will have markedly decreased chances of survival, which will not only drastically reduce the species' overall ability to weather the changing climate but will send ripple effects throughout the surrounding landscape. The team has also modeled possible mitigation scenarios.
Published Groundbreaking genome editing tools unlock new possibilities for precision medicine
(via sciencedaily.com) Original source A team of researchers has achieved a major breakthrough in genome editing technology. They've developed a cutting-edge method that combines the power of designer-recombinases with programmable DNA-binding domains to create precise and adaptable genome editing tools.
Published How seahorse-like toxins kill insects
(via sciencedaily.com) Original source Insect-killing bacteria typically release toxins to slay their hosts. The bacterium Photorhabdus luminescens, for example, pumps insect larvae full of the lethal 'Makes caterpillars floppy 1' (Mcf1) toxin, leading them to first become droopy and then dead. However, it has so far been a mystery how Mcf1 unfolds its devastating effect. Researchers successfully used cryo-electron microscopy (cryo-EM) and biochemical assays to characterize the first-ever Mcf1 structure, allowing them to propose a molecular mechanism of the toxin's action. Understanding how bacterial toxins perform their deadly task in such detail is very useful for engineering novel biopesticides, thereby reducing the use of barely specific chemical agents with harmful side effects for the ecosystem.
Published Using computers to design proteins allows researchers to make tunable hydrogels that can form both inside and outside of cells
(via sciencedaily.com) Original source New research demonstrates a new class of hydrogels that can form not just outside cells, but also inside of them. These hydrogels exhibited similar mechanical properties both inside and outside of cells, providing researchers with a new tool to group proteins together inside of cells.
Published DNA particles that mimic viruses hold promise as vaccines
(via sciencedaily.com) Original source Using a DNA-based delivery particle, researchers created a vaccine that can induce a strong antibody response against SARS-CoV-2.
Published Asparagus and orchids are more similar than you think
(via sciencedaily.com) Original source How is a beech leaf constructed? What determines the appearance of an asparagus? A new 'encyclopaedia' helps us learn more about the building blocks of plants. The encyclopaedia, probably the largest of its kind, could be used to improve targeted plant breeding efforts, to make them both more climate-resilient and more easily digestible.
Published 'Genomic time machine' reveals secrets of our DNA
(via sciencedaily.com) Original source Researchers reveal a novel method to uncover bits of our genetic blueprint that come from ancient genetic parasites, offering fresh insights into human evolution and health.
Published A non-allergenic wheat protein for growing better cultivated meat
(via sciencedaily.com) Original source As the world's population increases, cultivated or lab-grown meat -- animal muscle and fat cells grown in laboratory conditions -- has emerged as a potential way to satisfy future protein needs. And edible, inexpensive plant proteins could be used to grow these cell cultures. Now, researchers report that the non-allergenic wheat protein glutenin successfully grew striated muscle layers and flat fat layers, which could be combined to produce meat-like textures.
Published Scientists develop novel method to estimate biodiversity loss in Singapore over the past two centuries
(via sciencedaily.com) Original source Scientists have employed novel statistical methods to reveal the extent of biodiversity loss in Singapore over the past two centuries. The study paints the most accurate picture to date of the ecological impact of deforestation and urban development in the tropical city-state. From a comprehensive dataset, the study estimated that Singapore has lost 37 per cent of its species.
Published Researchers map genome for cats, dolphins, birds, and dozens of other animals
(via sciencedaily.com) Original source Researchers mapped genetic blueprints for 51 species including cats, dolphins, kangaroos, penguins, sharks, and turtles, a discovery that deepens our understanding of evolution and the links between humans and animals. The researchers developed novel algorithms and computer software that cut the sequencing time from months -- or decades in the case of the human genome -- to a matter of days.
Published Soap bark discovery offers a sustainability booster for the global vaccine market
(via sciencedaily.com) Original source A valuable molecule sourced from the soapbark tree and used as a key ingredient in vaccines, has been replicated in an alternative plant host for the first time, opening unprecedented opportunities for the vaccine industry.
Published Use it or lose it: How seagrasses conquered the sea
(via sciencedaily.com) Original source Seagrasses provide the foundation of one of the most highly biodiverse, yet vulnerable, coastal marine ecosystems globally. They arose in three independent lineages from their freshwater ancestors some 100 million years ago and are the only fully submerged, marine flowering plants. Moving to such a radically different environment is a rare evolutionary event and definitely not easy. How did they do it? New reference quality genomes provide important clues with relevance to their conservation and biotechnological application.
Published Achieving sustainable urban growth on a global scale
(via sciencedaily.com) Original source An international group of leading scientists call for an urgent change in the governance of urban expansion as the world's cities continue to grow at unprecedented rates.
Published How HIV smuggles its genetic material into the cell nucleus
(via sciencedaily.com) Original source Around one million individuals worldwide become infected with HIV, the virus that causes AIDS, each year. To replicate and spread the infection, the virus must smuggle its genetic material into the cell nucleus and integrate it into a chromosome. Research teams have now discovered that its capsid has evolved into a molecular transporter. As such, it can directly breach a crucial barrier, which normally protects the cell nucleus against viral invaders. This way of smuggling keeps the viral genome invisible to anti-viral sensors in the cytoplasm.
Published How macrophages regulate regenerative healing in spiny mice
(via sciencedaily.com) Original source A team of researchers is delving deeper into the science behind how spiny mice can regenerate lost tissue and using what they learn to trigger regeneration in other types of mice -- advances which one day may be translated into humans. Whereas adult laboratory mice heal injuries with scar tissue, spiny mice have the unique ability to regrow lost skin and regenerate musculoskeletal tissues in their body.
Published The underground network: Decoding the dynamics of plant-fungal symbiosis
(via sciencedaily.com) Original source The intricate dance of nature often unfolds in mysterious ways, hidden from the naked eye. At the heart of this enigmatic tango lies a vital partnership: the symbiosis between plants and a type of fungi known as arbuscular mycorrhizal (AM) fungi. New groundbreaking research delves into this partnership, revealing key insights that deepen our understanding of plant-AM fungi interactions and could lead to advances in sustainable agriculture.
Published Simulations show how HIV sneaks into the nucleus of the cell
(via sciencedaily.com) Original source A new study has revealed how HIV squirms its way into the nucleus as it invades a cell.
Published Unexpected biodiversity on the ocean floor
(via sciencedaily.com) Original source Hydrothermal vents and manganese nodule fields in the deep oceans contain more biodiversity than expected.
Published How does HIV get into the cell's cenetr to kickstart infection?
(via sciencedaily.com) Original source UNSW Sydney medical scientists have cracked a mystery whose solution has long eluded researchers. UNSW Sydney medical scientists have cracked a mystery whose solution has long eluded researchers.
Published DNA from preserved feces reveals ancient Japanese gut environment
(via sciencedaily.com) Original source DNA from ancient feces can offer archaeologists new clues about the life and health of Japanese people who lived thousands of years ago, according to a new study.