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Categories: Biology: Genetics, Environmental: Water

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Groundwater is a vital resource, sustaining plants and ecosystems, ensuring agricultural production and serving as a core component of drinking water supplies. However, climate change and anthropogenic pressures can threaten groundwater availability, especially in southwestern Europe. This threat was evaluated by a research team using multidecadal data from more than 12,000 groundwater wells in Portugal, Spain, France, and Italy. The surprising finding: Groundwater levels are not declining everywhere as widely believed, but primarily in semi-arid regions with intensive agriculture and frequent droughts. Declines are also observed in temperate regions associated with large urban areas. The authors conclude that, with suitable management practices, groundwater can be utilized sustainably.

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A study of horses -- which share many important similarities with humans in their chromosomes and pregnancies -- revealed that 42% of miscarriages and spontaneous abortions in the first two months of pregnancy were due to complications from an extra set of chromosomes, a condition called triploidy.

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Researchers reveal more about the tit-for-tat evolutionary changes occurring in both potato plants and the pathogen that caused the 1840s Irish potato famine.

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Using state of the art techniques, researchers use vibrations from traffic to measure underground soil moisture.

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With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its rules and context to draw functional information about the DNA sequences.

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A previously unknown defence mechanism in the brain prevents herpesvirus from infecting the brain's nerve cells.

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Researchers have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses. These macrophages are instrumental in repairing the pulmonary alveoli. This groundbreaking discovery promises to revolutionize our understanding of the post-infectious immune response and opens the door to new regenerative therapies.

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The process by which phages -- viruses that infect and replicate within bacteria -- enter cells has been studied for over 50 years. In a new study, researchers have used cutting-edge techniques to look at this process at the level of a single cell.

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Unravelling the complexities of circular RNAs (circRNAs) in cancer biology has positioned scientists on the cusp of revolutionary breakthroughs in the diagnosis and treatment of cancer. A new study predicts remarkable potential for circular RNAs to improve cancer treatment and patient outcomes within the next 5-10 years.

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The origins of life remain a major mystery. How were complex molecules able to form and remain intact for prolonged periods without disintegrating? A team has demonstrated a mechanism that could have enabled the first RNA molecules to stabilize in the primordial soup. When two RNA strands combine, their stability and lifespan increase significantly.

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Wild boars and red junglefowl gave rise to common pigs and chickens. These animals' genes evolved to express themselves differently, leading to signatures of domestication -- such as weaker bones and better viral resistance -- in pigs and chickens, according to a research team.

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Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to keep parts of the replication machinery from falling off the DNA strand.

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Much of the water in the West is transported across vast geographical areas by large infrastructure projects known as interbasin water transfers. Two of these projects in particular make up 85% of all energy-related greenhouse gas emissions associated with U.S. interbasin transfers -- one in Arizona and the other in California -- according to the new research.

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A new 3D printing method developed by engineers is so simple that it uses a polymer ink and salt water solution to create solid structures. The work has the potential to make materials manufacturing more sustainable and environmentally friendly.

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Higher levels of urinary metals such as cadmium, tungsten, uranium, cobalt, copper and zinc are linked to increased cardiovascular disease and mortality in a racially and ethnically diverse U.S. population, according to a new study.

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Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can differentiate between functional and faulty viral vectors at the single-particle level. This convenient and inexpensive technique will hopefully get us one step closer to advancing treatments for genetic disorders.

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Researchers transferred genes from simple organisms capable of regenerating their bodies into common fruit flies, more complex animals that cannot. They found the transferred gene suppressed an age-related intestinal issue in the flies. Their results suggest studying genes specific to animals with high regenerative capability may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.

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Hotter conditions prevent two tiny organisms working together for mutual benefit, new research shows.

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An international research team has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient.

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Clues to future sea level rise have been revealed by the first detailed maps of the underside of a floating ice shelf in Antarctica. An international research team deployed an unmanned submersible beneath the Dotson Ice Shelf in West Antarctica.