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Categories: Biology: Genetics, Geoscience: Earthquakes
Published AI deciphers new gene regulatory code in plants and makes accurate predictions for newly sequenced genomes



Elucidating the relationship between the sequences of non-coding regulatory elements and their target genes is key to understanding gene regulation and its variation between plant species and ecotypes. Now, an international research team developed deep learning models that link gene sequence data with mRNA copy number for several plant species and predicted the regulatory effect of gene sequence variation.
Published Barley plants fine-tune their root microbial communities through sugary secretions



Different types of barley recruit distinct communities of soil microbes to grow around their roots by releasing a custom mix of sugars and other compounds, according to a new study.
Published Food in sight? The liver is ready!



What happens in the body when we are hungry and see and smell food? A team of researchers has now been able to show in mice that adaptations in the liver mitochondria take place after only a few minutes. Stimulated by the activation of a group of nerve cells in the brain, the mitochondria of the liver cells change and prepare the liver for the adaptation of the sugar metabolism. The findings could open up new avenues for the treatment of type 2 diabetes.
Published Curiosity promotes biodiversity



Cichlid fishes exhibit differing degrees of curiosity. The cause for this lies in their genes, as reported by researchers. This trait influences the cichlids' ability to adapt to new habitats.
Published Cells may possess hidden communication system



Cells constantly navigate a dynamic environment, facing ever-changing conditions and challenges. But how do cells swiftly adapt to these environmental fluctuations? A new study is answering that question by challenging our understanding of how cells function. A team of researchers suggests that cells possess a previously unknown information processing system that allows them to make rapid decisions independent of their genes.
Published Researchers uncover 'parallel universe' in tomato genetics



Researchers have made a breakthrough for evolutionary biology of the Solanaceae family, which includes peppers, potatoes and petunias.
Published Color variants in cuckoos: The advantages of rareness



Every cuckoo is an adopted child -- raised by foster parents, into whose nest the cuckoo mother smuggled her egg. The cuckoo mother is aided in this subterfuge by her resemblance to a bird of prey. There are two variants of female cuckoos: a gray morph that looks like a sparrowhawk, and a rufous morph. Male cuckoos are always gray.
Published Unveiling the mysteries of cell division in embryos with timelapse photography



The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis is well-studied in the so-called somatic cells -- the cells that have a specialized function, like skin and muscle cells -- they remain elusive in the first cells of our bodies, the embryonic cells. Embryonic mitosis is notoriously difficult to study in vertebrates, as live functional analyses and -imaging of experimental embryos are technically limited, which makes it hard to track cells during embryogenesis.
Published Giant viruses infect deadly parasite



The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers have now discovered viruses that infect this harmful microbe. Named Naegleriavirus, these belong to the giant viruses, a group known for their unusually large particles and complex genomes.
Published Researchers unveil PI3K enzyme's dual accelerator and brake mechanisms



The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to slam on the breaks to this process.
Published Scientists unveil genetics behind development of gliding



Researchers explain the genomic and developmental basis of the patagium, the thin skin membrane that allows some mammalian species to soar through the air.
Published Researchers create artificial cells that act like living cells



Researchers describe the steps they took to manipulate DNA and proteins -- essential building blocks of life -- to create cells that look and act like cells from the body. This accomplishment, a first in the field, has implications for efforts in regenerative medicine, drug delivery systems and diagnostic tools.
Published Liquid droplets shape how cells respond to change



New research has shown that cells regulate cAMP/PKA signaling by forming liquid droplets that segregate excess PKA catalytic subunits where they can do no harm. Some cancers may block the formation of liquid droplets, leading to hyperactive signaling and tumor formation.
Published AI can improve Alzheimer's treatment through the 'gut-brain axis'



Researchers are using artificial intelligence to uncover the link between the gut microbiome and Alzheimer's disease. Previous studies showed that Alzheimer's disease patients have changes in their gut bacteria as the disease develops. The study outlines a computational method to determine how bacterial byproducts called metabolites interact with receptors on cells and contribute to Alzheimer's disease.
Published Scientists discover the cellular functions of a family of proteins integral to inflammatory diseases



In a scientific breakthrough, researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.
Published Protein network dynamics during cell division



An international team has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.
Published The enemy within: How pathogens spread unrecognized in the body



Some pathogens hide inside human cells to enhance their survival. Researchers have uncovered a unique tactic certain bacteria use to spread in the body without being detected by the immune system. In their study, they reveal the crucial role of a bacterial nanomachine in this infection process.
Published Key protein regulates immune response to viruses in mammal cells



Researchers have revealed the regulatory mechanism of a specific protein, TRBP, that plays a key role in balancing the immune response triggered by viral infections in mammal cells. These findings could help drive the development of antiviral therapies and nucleic acid medicines to treat genetic disorders.
Published Light show in living cells



Observing proteins precisely within cells is extremely important for many branches of research but has been a significant technical challenge -- especially in living cells, as the required fluorescent labeling had to be individually attached to each protein. The research group has now overcome this hurdle: With a method called 'vpCells,' it is possible to label many proteins simultaneously, using five different fluorescent colors.
Published Scientists trigger mini-earthquakes in the lab



Earthquakes and landslides are famously difficult to predict and prepare for. By studying a miniature version of the ground in the lab, scientists have demonstrated how these events can be triggered by a small external shock wave. Bring a flotation device: it involves the ground briefly turning into a liquid!