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Categories: Biology: Genetics, Geoscience: Landslides
Published New insights into what helps Salmonella cause infections
(via sciencedaily.com) Original source In a new study, researchers have discovered how a system of proteins, called TamAB, helps Salmonella survive under the harsh conditions inside macrophages.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging
(via sciencedaily.com) Original source Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.
Published New rice lines for Africa offer virus protection
(via sciencedaily.com) Original source The so-called Rice Yellow Mottle Virus (for short: RYMV) is responsible for high crop losses in Africa, particularly among small-scale farmers. A research team has now produced rice lines that are resistant to the disease by means of genome editing. The rice varieties are a preliminary step toward being able to generate resistant locally adapted elite varieties for small-scale food producers in Africa.
Published Spying on a shape-shifting protein
(via sciencedaily.com) Original source Researchers are using crystallography to gain a better understanding of how proteins shapeshift. The knowledge can provide valuable insight into stopping and treating diseases.
Published Study uncovers potential origins of life in ancient hot springs
(via sciencedaily.com) Original source A research team investigated how the emergence of the first living systems from inert geological materials happened on the Earth, more than 3.5 billion years ago. Scientists found that by mixing hydrogen, bicarbonate, and iron-rich magnetite under conditions mimicking relatively mild hydrothermal vent results in the formation of a spectrum of organic molecules, most notably including fatty acids stretching up to 18 carbon atoms in length.
Published Lab-grown retinas explain why people see colors dogs can't
(via sciencedaily.com) Original source With human retinas grown in a petri dish, researchers discovered how an offshoot of vitamin A generates the specialized cells that enable people to see millions of colors, an ability that dogs, cats, and other mammals do not possess. The findings increase understanding of color blindness, age-related vision loss, and other diseases linked to photoreceptor cells. They also demonstrate how genes instruct the human retina to make specific color-sensing cells, a process scientists thought was controlled by thyroid hormones.
Published Protein complex discovered to control DNA repair
(via sciencedaily.com) Original source The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched. A scientific team has now discovered a previously unrecognized control point for these processes. This could lead to a new approach for the development of cancer therapies aimed at inhibiting the repair of damaged cancer cells.
Published Toxic algae blooms: Study assesses potential health hazards to humans
(via sciencedaily.com) Original source Water samples from 20 sites were tested using a panel of immortalized human cell lines corresponding to the liver, kidney and brain to measure cytotoxicity. Results show that each control toxin induced a consistent pattern of cytotoxicity in the panel of human cell lines assayed. Known toxins were seen only during blooms. Because cell toxicity was seen in the absence of blooms, it suggests that there might be either emergent toxins or a combination of toxins present at those times. Findings suggest that other toxins with the potential to be harmful to human health may be present in the lagoon.
Published A new type of plant metalloreductase maintains root growth under low phosphorus
(via sciencedaily.com) Original source Phosphorus is essential for undisturbed plant growth and development. However, in many soils, phosphorus is only poorly available. One mechanism used by plants to increase phosphorus availability is the release of malate, an organic acid, which can form complexes with iron or aluminium in the soil, thereby liberating sorbed phosphate. However, this response can also result in iron overaccumulation, which can inhibit root growth.
Published Smart skin bacteria are able to secrete and produce molecules to treat acne
(via sciencedaily.com) Original source An experimental study has shown that a type of skin bacterium can efficiently be engineered to produce a protein to regulate sebum production. This application could treat acne without compromising the homeostasis of the entire skin microbiome.
Published Large-scale mapping of pig genes could pave the way for new human medicines
(via sciencedaily.com) Original source Researchers have carried out complex genetic analyses of hundreds of pigs and humans to identify differences and similarities. This new knowledge can be used to ensure healthier pigs for farmers and can help the pharmaceutical industry breed better laboratory pigs for testing new medicines.
Published Life span increases in mice when specific brain cells are activated
(via sciencedaily.com) Original source A new study identifies, in mice, a critical communication pathway connecting the brain and the body's fat tissue in a feedback loop that appears central to energy production throughout the body. The research suggests that the gradual deterioration of this feedback loop contributes to the increasing health problems that are typical of natural aging.
Published Researchers discover molecular 'barcode' used by bacteria to secrete toxins
(via sciencedaily.com) Original source Researchers have discovered a molecular 'barcode' system used by disease-causing bacteria to distinguish between beneficial and toxic molecules.
Published Important membrane transport mechanism in pathogenic bacteria
(via sciencedaily.com) Original source Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane. Like a forklift, a soluble protein outside the bacterium transports the substance to the 'elevator' and unloads its cargo there. The freight elevator transports it to the inside of the cell, in other words to another floor.
Published Evolution is not as random as previously thought
(via sciencedaily.com) Original source A groundbreaking study has found that evolution is not as unpredictable as previously thought, which could allow scientists to explore which genes could be useful to tackle real-world issues such as antibiotic resistance, disease and climate change. The study challenges the long-standing belief about the unpredictability of evolution, and has found that the evolutionary trajectory of a genome may be influenced by its evolutionary history, rather than determined by numerous factors and historical accidents.
Published The snail or the egg?
(via sciencedaily.com) Original source Animals reproduce in one of two distinct ways: egg-laying or live birth. By studying an evolutionarily recent transition from egg-laying to live-bearing in a marine snail, collaborative research has shed new light on the genetic changes that allow organisms to make the switch.
Published Scientists engineer plant microbiome to protect crops against disease
(via sciencedaily.com) Original source Scientists have engineered the microbiome of plants for the first time, boosting the prevalence of 'good' bacteria that protect the plant from disease. The findings could substantially reduce the need for environmentally destructive pesticides.
Published New roles for autophagy genes in cellular waste management and aging
(via sciencedaily.com) Original source Autophagy, which declines with age, may hold more mysteries than researchers previously suspected. Scientists have now uncovered possible novel functions for various autophagy genes, which may control different forms of disposal including misfolded proteins -- and ultimately affect aging.
Published The surprisingly resourceful ways bacteria thrive in the human gut
(via sciencedaily.com) Original source New research shows that some groups of bacteria in the gut are amazingly resourceful, with a large repertoire of genes that help them generate energy for themselves and potentially influence human health as well.
Published Nematode proteins shed light on infertility
(via sciencedaily.com) Original source Biologists developed a method for illuminating the intricate interactions of the synaptonemal complex in the nematode C. elegans. The authors identified a trio of protein segments that guide chromosomal interactions, and pinpointed the location where they interact with each other. Their novel method uses a technique known as genetic suppressor screening, which can serve as a blueprint for research on large cellular assemblies that resist traditional structural analysis.