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Categories: Biology: Genetics, Geoscience: Landslides
Published How plants use sugar to produce roots



Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. Botanists have demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to the research team leader.
Published Synthetic biology: proteins set vesicles in motion



Biophysicists have designed a new cell-like transport system that represents an important milestone on the road to artificial cells.
Published Cancer cells use a new fuel in absence of sugar



Researchers have discovered a new nutrient source that pancreatic cancer cells use to grow. The molecule, uridine, offers insight into both biochemical processes and possible therapeutic pathways. The findings show that cancer cells can adapt when they don't have access to glucose.
Published Watch these cells rapidly create protrusions for exploration and movement



In order to move, cells must be able to rapidly change shape. A team of researchers show that cells achieve this by storing extra 'skin' in folds and bumps on their surface. This cell surface excess can be rapidly deployed to cover temporary protrusions and then folded away for next time.
Published Scales or feathers? It all comes down to a few genes



Scales, spines, feathers and hair are examples of vertebrate skin appendages, which constitute a remarkably diverse group of micro-organs. Despite their natural multitude of forms, these appendages share early developmental processes at the embryonic stage. Researchers have discovered how to permanently transform the scales that normally cover the feet of chickens into feathers, by specifically modifying the expression of certain genes.
Published What did the earliest animals look like?



Surprisingly, genome comparisons have failed to resolve a major question in animal evolution: Which living animals are the descendants of the earliest animals to evolve in the world's oceans? Scientists performed a detailed chromosomal analysis that comes down definitively in favor of comb jellies, or ctenophores, as the most recent common ancestor of all animals, or the sister taxa to all animals. Sponges evolved later.
Published A channel involved in pain sensation can also suppress it



Pain is good. It's the body's way to keep an animal from harming itself or repeating a dangerous mistake. But sometimes the debilitating sensation can get in the way. So evolution has devised ways to tamp that response down under certain circumstances.
Published Researchers reveal DNA repair mechanism



A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.
Published How superbug A. baumannii survives metal stress and resists antibiotics



The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting response. The World Health Organization (WHO) recognizes it as one of the three top pathogens in critical need of new antibiotic therapies. Now, an international team, led by Macquarie University researchers Dr. Ram Maharjan and Associate Professor Amy Cain, have discovered how the superbug can survive harsh environments and then rebound, causing deadly infections. They have found a single protein that acts as a master regulator. When the protein is damaged, the bug loses its superpowers allowing it to be controlled, in a lab setting. The research is published this month in Nucleic Acids Research.
Published Phage structure captured, to benefit biotech applications



Researchers have mapped out what a commonly-used form of phage looks like, which will help design better uses in future.
Published Researcher uses mammal DNA to zoom into the human genome with unprecedented resolution



Scientists have precisely identified base pairs of the human genome that remained consistent over millions of years of mammalian evolution, and which play a crucial role in human disease. The team analyzed the genomes of 240 mammals, including humans and identified base pairs that were 'constrained' -- meaning they remained generally consistent -- across mammal species over the course of evolution. The most constrained base pairs in mammals were over seven times more likely to be causal for human disease and complex trait, and over 11 times more likely when researchers looked at the most constrained base pairs in primates alone.
Published A look inside stem cells helps create personalized regenerative medicine



Researchers have examined a specific type of stem cell with an intracellular toolkit to determine which cells are most likely to create effective cell therapies.
Published Ancestral mitoviruses discovered in mycorrhizal fungi



A new group of mitochondrial viruses confined to the arbuscular mycorrhizal fungi Glomeromycotina may represent an ancestral lineage of mitoviruses.
Published New research could help breed for less 'spooky' horses



Researchers are working to identify genes that influence horses' tendency to react to perceived danger.
Published Crops evolved by swapping genetic modules between cells



Comparing individual cells across corn, sorghum, and millet reveals evolutionary differences among these important cereal crops, according to a new study. The findings bring researchers closer to pinpointing which genes control important agricultural traits such as drought tolerance, which will help scientists faced with a changing climate adapt crops to drier environments.
Published Scientists develop gene silencing DNA enzyme that can target a single molecule



Researchers have developed a DNA enzyme -- or DNAzyme -- that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact. This breakthrough 'gene silencing' technology could revolutionize the development of DNAzymes for treating cancer, infectious diseases and neurological disorders.
Published T cells can activate themselves to fight tumors



Scientists find an auto-signaling mechanism driving the T cell anti-tumor response; findings may inspire new cancer therapeutics and biomarkers.
Published New probe aids novel findings on cell functions



New research shows the use of a new cellular probe helped discover new findings about certain cellular processes.
Published An unprecedented view of gene regulation



Using a new technique, researchers have shown that they can map interactions between gene promoters and enhancers with 100 times higher resolution than has previously been possible.
Published Elucidating the mysteries of enzyme evolution at the macromolecular level



Researchers have made a major breakthrough earlier this year in the field of evolutionary conservation of molecular dynamics in enzymes. Their work points to potential applications in health, including the development of new drugs to treat serious diseases such as cancer or to counter antibiotic resistance.