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Categories: Biology: Genetics, Geoscience: Earth Science
Published Discovery of a new population of macrophages promoting lung repair after viral infections
(via sciencedaily.com) Original source Researchers have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses. These macrophages are instrumental in repairing the pulmonary alveoli. This groundbreaking discovery promises to revolutionize our understanding of the post-infectious immune response and opens the door to new regenerative therapies.
Published Coinfecting viruses impede each other's ability to enter cells
(via sciencedaily.com) Original source The process by which phages -- viruses that infect and replicate within bacteria -- enter cells has been studied for over 50 years. In a new study, researchers have used cutting-edge techniques to look at this process at the level of a single cell.
Published Born to modulate: Researchers reveal origins of climate-controlling particles
(via sciencedaily.com) Original source Aerosol particles imbue climate models with uncertainty. New work reveals where in the world and under what conditions new particles are born.
Published Circular RNAs: The new frontier in cancer research
(via sciencedaily.com) Original source Unravelling the complexities of circular RNAs (circRNAs) in cancer biology has positioned scientists on the cusp of revolutionary breakthroughs in the diagnosis and treatment of cancer. A new study predicts remarkable potential for circular RNAs to improve cancer treatment and patient outcomes within the next 5-10 years.
Published Sea level changes shaped early life on Earth, fossil study reveals
(via sciencedaily.com) Original source Shifts in the Earth's continental plates that drove long-term changes in sea level set the stage for the evolution of the earliest animals on Earth, a study suggests.
Published Scientists find a human 'fingerprint' in the upper troposphere's increasing ozone
(via sciencedaily.com) Original source Scientists confirmed that much of ozone's increase in the upper troposphere is likely due to humans. A team detected a clear signal of human influence on upper tropospheric ozone trends in a 17-year satellite record starting in 2005.
Published What gave the first molecules their stability?
(via sciencedaily.com) Original source The origins of life remain a major mystery. How were complex molecules able to form and remain intact for prolonged periods without disintegrating? A team has demonstrated a mechanism that could have enabled the first RNA molecules to stabilize in the primordial soup. When two RNA strands combine, their stability and lifespan increase significantly.
Published Genetic signatures of domestication identified in pigs, chickens
(via sciencedaily.com) Original source Wild boars and red junglefowl gave rise to common pigs and chickens. These animals' genes evolved to express themselves differently, leading to signatures of domestication -- such as weaker bones and better viral resistance -- in pigs and chickens, according to a research team.
Published Retreat of tropical glaciers foreshadows changing climate's effect on the global ice
(via sciencedaily.com) Original source As they are in many places around the globe, glaciers perched high in the Andes Mountains are shrinking. Now, researchers have uncovered evidence that the high-altitude tropical ice fields are likely smaller than they've been at any time since the last ice age ended 11,700 years ago.
Published When it comes to DNA replication, humans and baker's yeast are more alike than different
(via sciencedaily.com) Original source Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the first time a molecular complex -- called CTF18-RFC in humans and Ctf18-RFC in yeast -- that loads a 'clamp' onto DNA to keep parts of the replication machinery from falling off the DNA strand.
Published Novel nanosensing technique for quality control of viral vectors in gene therapy
(via sciencedaily.com) Original source Researchers develop a nanosensing platform that can assess the quality of individual viral vector particles Viral vectors hold much potential for gene editing and gene therapy, but there is a pressing need to develop quality control methods to minimize potential side effects on patients. Addressing this, researchers from Japan developed a nanosensing-based approach that can differentiate between functional and faulty viral vectors at the single-particle level. This convenient and inexpensive technique will hopefully get us one step closer to advancing treatments for genetic disorders.
Published Talking about regeneration
(via sciencedaily.com) Original source Researchers transferred genes from simple organisms capable of regenerating their bodies into common fruit flies, more complex animals that cannot. They found the transferred gene suppressed an age-related intestinal issue in the flies. Their results suggest studying genes specific to animals with high regenerative capability may uncover new mechanisms for rejuvenating stem cell function and extending the healthy lifespan of unrelated organisms.
Published Tipping risks from overshooting 1.5 °C can be minimized if warming is swiftly reversed
(via sciencedaily.com) Original source Current climate policies imply a high risk for tipping of critical Earth system elements, even if temperatures return to below 1.5 C of global warming after a period of overshoot. A new study indicates that this risk can be minimized if the warming is swiftly reversed. That is why reducing emissions in the current decade is crucial for the stability of the Earth systems functions, researchers write. They analyzed the tipping risks for four interconnected core climate tipping elements: the Greenland Ice Sheet, the West Antarctic Ice Sheet, the Atlantic Meridional Overturning Circulation (AMOC), and the Amazon Rainforest.
Published Mass extinction 66 million years ago triggered rapid evolution of bird genomes
(via sciencedaily.com) Original source Study finds that the mass extinction caused by an asteroid about 66 million years ago led to critical changes in bird genomes that ultimately sparked the incredibly diversity living birds.
Published The next generation of RNA chips
(via sciencedaily.com) Original source An international research team has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time of RNA chips used in biotechnological and medical research. The chemical synthesis of these chips is now twice as fast and seven times more efficient.
Published Downwind states face disproportionate burden of air pollution
(via sciencedaily.com) Original source A recent U.S. Supreme Court decision to block a federal rule curbing interstate air pollution further complicates efforts to reduce emissions and adds to an already disproportionate burden on 'downwind' states, according to researchers.
Published Smell reports reveal the need to expand urban air quality monitoring, say researchers
(via sciencedaily.com) Original source Researchers have uncovered surprising insights into the Vancouver region's 'smellscape' using data from the Smell Vancouver app. Analyzing 549 reports from one year of app data, they discovered that 'rotten' and 'chemical' odours dominated, making up about 65 per cent of submissions. These unpleasant smells were linked to self-reported health issues like headaches and anxiety, leading some residents to change their behaviours, like closing windows even in stifling-hot weather.
Published Scientists devise method to secure Earth's biodiversity on the moon
(via sciencedaily.com) Original source New research led proposes a plan to safeguard Earth's imperiled biodiversity by cryogenically preserving biological material on the moon. The moon's permanently shadowed craters are cold enough for cryogenic preservation without the need for electricity or liquid nitrogen.
Published Climate change means that tropical cyclones in Southeast Asia are developing faster, lasting longer
(via sciencedaily.com) Original source A study reveals that tropical cyclones in Southeast Asia are now forming closer to coastlines, intensifying more rapidly, and lingering longer over land.
Published New principle for treating tuberculosis
(via sciencedaily.com) Original source Researchers have succeeded in identifying and synthesizing a group of molecules that can act against the cause of tuberculosis in a new way. They describe that the so-called callyaerins act against the infectious disease by employing a fundamentally different mechanism compared to antibiotic agents used to date.