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Categories: Biology: Genetics, Geoscience: Earth Science
Published Researchers uncover genetic factors for severe Lassa fever



Researchers report the results of the first ever genome-wide association study (GWAS) of a biosafety level 4 (BSL-4) virus. The team found two key human genetic factors that could help explain why some people develop severe Lassa fever, and a set of LARGE1 variants linked to a reduced chance of getting Lassa fever. The work could lay the foundation for better treatments for Lassa fever and other similar diseases. The scientists are already working on a similar genetics study of Ebola susceptibility.
Published Ice cores provide first documentation of rapid Antarctic ice loss in the past



Researchers have uncovered the first direct evidence that the West Antarctic Ice Sheet shrunk suddenly and dramatically at the end of the Last Ice Age, around eight thousand years ago. The evidence, contained within an ice core, shows that in one location the ice sheet thinned by 450 meters -- that's more than the height of the Empire State Building -- in just under 200 years.
Published Are environmental toxins putting future generations at risk?



In a study that signals potential reproductive and health complications in humans, now and for future generations, researchers have concluded that fathers exposed to environmental toxins, notably DDT, may produce sperm with health consequences for their children.
Published Ancient rocks improve understanding of tectonic activity between earthquakes



Rocks once buried deep in ancient subduction zones -- where tectonic plates collide -- could help scientists make better predictions of how these zones behave during the years between major earthquakes, according to a research team.
Published What turned Earth into a giant snowball 700 million years ago? Scientists now have an answer



Inspired during field work in South Australia's Flinders Ranges, geoscientists have proposed that all-time low volcanic carbon dioxide emissions triggered a 57-million-year-long global 'Sturtian' ice age.
Published Replacing animal-based foods with alternative proteins would unlock land for carbon removal



Researchers report that replacing 50% of animal products with alternative proteins by 2050 could free up enough agricultural land to generate renewable energy equivalent in volume to today's coal-generated power while simultaneously removing substantial CO2 from the atmosphere.
Published New research uncovers biological drivers of heart disease risk



Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly connected to cardiovascular disease, limiting efforts to develop therapeutics. To streamline analysis of hundreds of genetic variants associated with coronary artery disease (CAD), a team of researchers combined multiple sequencing and experimental techniques to map the relationship between known CAD variants and the biological pathways they impact.
Published New study sheds new light on forests' role in climate and water cycle



Forests, which cover a third of Earth's land surface, are pivotal in carbon storage and the water cycle, though the full scope of their impact remains to be fully understood. In a new study, researchers provide new insights into the complex role forests play in the climate system and water cycle.
Published New approach to tackling bacterial infections identified



Researchers have identified a new approach to controlling bacterial infections. The team found a way to turn on a vital bacterial defense mechanism to fight and manage bacterial infections. The defense system, called cyclic oligonucleotide-based antiphage signaling system (CBASS), is a natural mechanism used by certain bacteria to protect themselves from viral attacks. Bacteria self-destruct as a means to prevent the spread of virus to other bacterial cells in the population.
Published Researchers discover key to molecular mystery of how plants respond to changing conditions



A team of researchers recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change -- either internally or in the external environment -- to thrive in good times or survive the bad times? The research, focused on plants, identifies the interactions between four compounds: pectin, receptor proteins FERONIA and LLG1 and the signal RALF peptide.
Published Scientists develop new biocontainment method for industrial organisms



Researchers have developed a new biocontainment method for limiting the escape of genetically engineered organisms used in industrial processes.
Published A new origin story for deadly Seattle fault



The Seattle fault zone is a network of shallow faults slicing through the lowlands of Puget Sound, threatening to create damaging earthquakes for the more than four million people who live there. A new origin story, proposed in a new study, could explain the fault system's earliest history and help scientists improve hazard modeling for the densely populated region.
Published Extra fingers and hearts: Pinpointing changes to our genetic instructions that disrupt development



Scientists can now predict which single-letter changes to the DNA within our genomes will alter genetic instructions and disrupt development, leading to changes such as the growth of extra digits and hearts. Such knowledge opens the door to predictions of which enhancer variants underlie disease in order to harness the full potential of our genomes for better human health.
Published Computer-engineered DNA to study cell identities



A new computer program allows scientists to design synthetic DNA segments that indicate, in real time, the state of cells. It will be used to screen for anti-cancer or viral infections drugs, or to improve gene and cell-based immunotherapies.
Published Smells like evolution: Fruit flies reveal surprises in chemical sensing



New study reveals how gene expression shapes the diverse smelling and tasting abilities of different fly species. Most genes are surprisingly stable, but thousands have evolved to create unique olfactory landscapes. Sex differences in sensing are widespread and involve specific cell types in key tissues. The study provides insights into the evolution of sensory systems in general, with potential implications for understanding human olfaction.
Published Study challenges the classical view of the origin of the Antarctic Circumpolar Current and warns of its vulnerability



The Circumpolar Current works as a regulator of the planet's climate. Its origins were thought to have caused the formation of the permanent ice in Antarctica about 34 million years ago. Now, a study has cast doubt on this theory, and has changed the understanding of how the ice sheet in Antarctic developed in the past, and what this could mean in the future as the planet's climate changes.
Published Vitamin B12 adaptability in Antarctic algae has implications for climate change, life in the Southern Ocean



The algae P. antarctica has two forms of the enzyme that makes the amino acid methionine, one needing B12, and one that is slower, but doesn't need it. This means it has the ability to adapt and survive with low B12 availability. The presence of the MetE gene in P. antarctica gives the algae the ability to adapt to lower vitamin B12 availability, giving it a potential advantage to bloom in the early austral spring when bacterial production is low. P. antarctica takes in the CO2 and releases oxygen through photosynthesis. Understanding its ability to grow in environments with low vitamin B12 availability can help climate modelers make more accurate predictions.
Published Understanding how soil traps carbon



With 2,500 billion tons of carbon, soil is one of Earth's largest carbon sinks. Researchers used experiments and computational modeling to study interactions between carbon molecules and clay minerals in soil. New research gives clues to why some plant-based carbon molecules are sequestered in soils but others are respired as CO2. Findings show that electrostatic charges, surrounding nutrients in soil and competition from other molecules all play roles in facilitating carbon trapping.
Published In a warming world, climate scientists consider category 6 hurricanes



For more than 50 years, the National Hurricane Center has used the Saffir-Simpson Windscale to communicate the risk of property damage; it labels a hurricane on a scale from Category 1 (wind speeds between 74 -- 95 mph) to Category 5 (wind speeds of 158 mph or greater). But as increasing ocean temperatures contribute to ever more intense and destructive hurricanes, climate scientists wondered whether the open-ended Category 5 is sufficient to communicate the risk of hurricane damage in a warming climate.
Published Scientists see an ultra-fast movement on surface of HIV virus



Seeing a glycoprotein on the envelope of the HIV virus snap open and shut in mere millionths of a second is giving investigators a new handle on the surface of the virus that could lead to broadly neutralizing antibodies for an AIDS vaccine. Being able to attach an antibody specifically to this little structure that would prevent it from popping open would be key.