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Categories: Biology: Genetics, Space: Exploration
Published Degradation of cell wall key in the spread of antibiotic resistance



A study provides new clues in the understanding of how antibiotic resistance spreads. The study shows how an enzyme breaks down the bacteria's protective outer layer, the cell wall, and thus facilitates the transfer of genes for resistance to antibiotics.
Published Researchers thwart resistant bacteria's strategy



Bacteria are experts at evolving resistance to antibiotics. One resistance strategy is to cover their cell walls in sticky and gooey biofilm that antibiotics cannot penetrate. A new discovery could put a stop to this strategy.
Published This desert moss has the potential to grow on Mars



The desert moss Syntrichia caninervis is a promising candidate for Mars colonization thanks to its extreme ability to tolerate harsh conditions lethal to most life forms. The moss is well known for its ability to tolerate drought conditions, but researchers now report that it can also survive freezing temperatures as low as 196 C, high levels of gamma radiation, and simulated Martian conditions involving these three stressors combined. In all cases, prior dehydration seemed to help the plants cope.
Published Tiny bright objects discovered at dawn of universe baffle scientists



A recent discovery by NASA's James Webb Space Telescope (JWST) confirmed that luminous, very red objects previously detected in the early universe upend conventional thinking about the origins and evolution of galaxies and their supermassive black holes.
Published Too many missing satellite galaxies found



Bringing us one step closer to solving the 'missing satellites problem,' researchers have discovered two new satellite galaxies.
Published New class of Mars quakes reveals daily meteorite strikes



An international team of researchers combine orbital imagery with seismological data from NASA's Mars InSight lander to derive a new impact rate for meteorite strikes on Mars. Seismology also offers a new tool for determining the density of Mars' craters and the age of different regions of a planet.
Published New deep-learning model outperforms Google AI system in predicting peptide structures



Researchers have developed a deep-learning model, called PepFlow, that can predict all possible shapes of peptides -- chains of amino acids that are shorter than proteins, but perform similar biological functions. Peptides are known to be highly flexible, taking on a wide range of folding patterns, and are thus involved in many biological processes of interest to researchers in the development of therapeutics.
Published Last surviving woolly mammoths were inbred but not doomed to extinction



The last population of woolly mammoths was isolated on Wrangel Island off the coast of Siberia 10,000 years ago, when sea levels rose and cut the mountainous island off from the mainland. A new genomic analysis reveals that the isolated mammoths, who lived on the island for the subsequent 6,000 years, originated from at most 8 individuals but grew to 200--300 individuals within 20 generations. The researchers report that the Wrangel Island mammoths' genomes showed signs of inbreeding and low genetic diversity but not to the extent that it can explain their ultimate (and mysterious) extinction.
Published A promising weapon against measles



What happens when measles virus meets a human cell? The viral machinery unfolds in just the right way to reveal key pieces that let it fuse itself into the host cell membrane.
Published Potent therapy candidate for fatal prion diseases



Scientists have developed a gene-silencing tool that shows promise as a therapy against fatal prion diseases. The tool, a streamlined epigenetic editor, paves the way for a new class of genetic approaches to treat certain diseases.
Published New, holistic way to teach synthetic biology



Synthetic biology combines principles from science, engineering and social science, creating emerging technologies such as alternative meats and mRNA vaccines; Deconstructing synthetic biology across scales gives rise to new approach to uniting traditional disciplines; Case studies offer a modular, accessible approach to teaching at different institutions.
Published Scientists discover genetic 'off switch' in legume plants that limits biological ability to source nutrients



A genetic 'off switch' that shuts down the process in which legume plants convert atmospheric nitrogen into nutrients has been identified for the first time by a team of international scientists.
Published Precision instrument bolsters efforts to find elusive dark energy



Dark energy -- a mysterious force pushing the universe apart at an ever-increasing rate -- was discovered 26 years ago, and ever since, scientists have been searching for a new and exotic particle causing the expansion. Physicists combined an optical lattice with an atom interferometer to hold atoms in place for up to 70 seconds -- a record for an atom interferometer -- allowing them to more precisely test for deviations from the accepted theory of gravity that could be caused by dark energy particles such as chameleons or symmetrons. Though they detected no anomalies, they're improving the experiment to perform more sensitive tests of gravity, including whether gravity is quantized.
Published Cell division: Before commitment, a very long engagement



Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours -- sometimes more than a day -- in a reversible intermediate state, according to a new discovery. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.
Published New tool enables faster, more cost-effective genome editing of traits to improve agriculture sustainability



New research had the goal of reducing the time and cost it takes to bring an improved crop to the marketplace to improve agriculture sustainability.
Published Unlocking the world of bacteria



Bacteria possess unique traits with great potential for benefiting society. However, current genetic engineering methods to harness these advantages are limited to a small fraction of bacterial species. A team has now introduced a novel approach that can make many more bacteria amenable to genetic engineering. Their method, called IMPRINT, uses cell-free systems to enhance DNA transformation across various bacterial strains.
Published The on-and-off affair in DNA



Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via the interactions of two other proteins and histone marks. The molecular mechanisms demonstrate that rather than functioning as a simple 'off switch,' H3K9 methylation is more like a 'dimmer switch' that fine-tunes DNA transcription. The discovery suggests there might be similar mechanisms in other organisms, too.
Published Pillars of creation star in new visualization from NASA's Hubble and Webb telescopes



Made famous in 1995 by NASA's Hubble Space Telescope, the Pillars of Creation in the heart of the Eagle Nebula have captured imaginations worldwide with their arresting, ethereal beauty. Now, NASA has released a new 3D visualization of these towering celestial structures using data from NASA's Hubble and James Webb space telescopes. This is the most comprehensive and detailed multiwavelength movie yet of these star-birthing clouds.
Published Predicting changes inside astronauts' bodies during space travel through blood sample analysis



The human body undergoes various transformations in space. However, a direct examination of organs and tissues is challenging. This study successfully identified these changes inside the body by analyzing tiny quantities of DNA and RNA molecules released from various tissues into the bloodstream while the astronauts were on the International Space Station (ISS).
Published Revealing the dynamic choreography inside multilayer vesicles



Our cells and the machinery inside them are engaged in a constant dance. This dance involves some surprisingly complicated choreography within the lipid bilayers that comprise cell membranes and vesicles -- structures that transport waste or food within cells. In a recent paper, researchers shed some light on how these vesicles self-assemble, knowledge that could help scientists design bio-inspired vesicles for drug-delivery or inspire them to create life-like synthetic materials.