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Categories: Biology: Genetics, Space: Exploration
Published How killifish embryos use suspended animation to survive over 8 months of drought



The African turquoise killifish lives in ephemeral ponds in Zimbabwe and Mozambique. To survive the annual dry season, the fish's embryos enter a state of extreme suspended animation or 'diapause' for approximately 8 months. Now, researchers have uncovered the mechanisms that enabled the killifish to evolve this extreme survival state.
Published Investigating the origin of circatidal rhythms in freshwater snails



While most organisms have biological clocks synchronized with the day-night cycle (circadian rhythms), marine animals in tidal areas have also developed circatidal rhythms to align with the tidal cycle. Comparing the activity and genetic expression of snails from tidal and non-tidal areas, researchers demonstrate that circatidal rhythms develop as snails adapt to tidal environments. These findings highlight the flexibility of biological clocks, enabling organisms to adjust their rhythms according to the environment.
Published Key role of plant-bacteria communication for the assembly of a healthy plant microbiome supporting sustainable plant nutrition



In an interdisciplinary study, researchers discovered that symbiotic bacteria communicate with legume plants through specific molecules and that this communication influences which bacteria grow near the plant roots. The findings provide insights into how plants and soil bacteria form beneficial partnerships for nutrient uptake and resilience. These results are a step towards understanding how communication between plants and soil bacteria can lead to specific beneficial associations providing plants with nutrients.
Published Birth of universe's earliest galaxies observed for first time



Researchers have now seen the formation of three of the earliest galaxies in the universe, more than 13 billion years ago. The sensational discovery contributes important knowledge about the universe.
Published New 'atlas' provides unprecedented insights on how genes function in early embryo development



Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.
Published Intriguing nearby world sized between Earth, Venus



Astronomers have discovered a planet between the sizes of Earth and Venus only 40 light-years away.
Published Planet hunters unveil massive catalog of strange worlds



While thousands of planets have been discovered around other stars, relatively little is known about them. A NASA catalog featuring 126 exotic, newly discovered worlds includes detailed measurements that allow for comparisons with our own solar system.
Published Novel approach to interrogate tissue-specific protein-protein interactions



Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing.
Published First pictures from Euclid satellite reveal billions of orphan stars



The first scientific pictures from the Euclid satellite mission have revealed more than 1,500 billion orphan stars scattered throughout the Perseus cluster of galaxies.
Published Potentially habitable 'exo-Venus' with Earth-like temperature discovered



Astronomers have made the rare and tantalizing discovery of an Earth-like exoplanet 40 light-years away that may be just a little warmer than our own world. The potentially-habitable planet, named Gliese 12 b, orbits its host star every 12.8 days, is comparable in size to Venus -- so slightly smaller than Earth -- and has an estimated surface temperature of 42 C (107 F), which is lower than most of the 5,000-odd exoplanets confirmed so far. That is assuming it has no atmosphere, however, which is the crucial next step to establishing if it is habitable.
Published Tracking down the genetic causes of lupus to personalize treatment



Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these therapies get to the patients who will benefit, work is needed to identify the specific mutations behind each patient's disease. Researchers now report several dozen mutations associated with oversensitive toll-like receptors -- a major cause of autoimmune disease -- and linked two mutations to patients.
Published Sexual parasitism helped anglerfish invade the deep sea during a time of global warming



Members of the vertebrate group including anglerfishes are unique in possessing a characteristic known as sexual parasitism, in which males temporarily attach or permanently fuse with females to mate. Now, researchers show that sexual parasitism arose during a time of major global warming and rapid transition for anglerfishes from the ocean floor to the deep, open sea.
Published Gene could unlock big wheat yields for a growing population



A study has discovered molecular pathways regulated by a gene traditionally used to control wheat-flowering behavior could be altered to achieve greater yields.
Published Exploring diversity in cell division



Animals and fungi predominantly use two different modes of cell division -- called open and closed mitosis, respectively. A new study has shown that different species of Ichthyosporea -- marine protists that are close relatives of both animals and fungi -- use either open and closed mitosis, closely correlated to whether the species has multinucleate life cycle stages. The study demonstrates the way animals do cell division might have evolved long before animals themselves did and how this is linked to an organism's life cycle.
Published Sweet move: a modified sugar enhances antisense oligonucleotide safety and efficacy



Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.
Published Using wobbling stellar material, astronomers measure the spin of a supermassive black hole for the first time



Astronomers have a new way to measure how fast a black hole spins, by using the wobbly aftermath from its stellar feasting. The results offer a new way to probe supermassive black holes and their evolution across the universe.
Published Roots are a key to drought-tolerant maize



Maize can grow successfully in very different local conditions. An international study has now demonstrated the important role of the plant root system. The researchers analyzed more than 9,000 varieties in the study and were able to show that their roots varied considerably -- depending on how dry the location is where each variety was cultivated. They were also able to identify an important gene that plays a role in the plant's ability to adapt. This gene could be the key to developing varieties of maize that cope better with climate change.
Published Study finds widespread 'cell cannibalism,' related phenomena across tree of life



Researchers describe cell-in-cell phenomena in which one cell engulfs and sometimes consumes another. The study shows that cases of this behavior, including cell cannibalism, are widespread across the tree of life. The findings challenge the common perception that cell-in-cell events are largely restricted to cancer cells. Rather, these events appear to be common across diverse organisms, from single-celled amoebas to complex multicellular animals.
Published Studies reveal cell-by-cell changes caused when pig hearts and kidneys are transplanted into humans



Two new studies detail the changes seen at the single-cell level in pig organs and recipient human bodies before, during, and just after the xenotransplantation surgeries in the decedents.
Published Clarifying the cellular mechanisms underlying periodontitis with an improved animal model



Although periodontitis is an extremely prevalent disorder, it is challenging to conduct detailed and comprehensive analyses of its progression at the cellular level. Recently, researchers developed an improved periodontitis mouse model that simplifies the collection and analysis of multiple periodontal tissue types. Using this model, they clarified the role of an important signaling pathway in the inflammatory response of periodontal tissue, paving the way for better diagnostic and therapeutic strategies for periodontitis.