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Categories: Biology: Genetics, Space: Exploration
Published Key protein in blood vessel's growth identified
(via sciencedaily.com) Original source New research identifies the class II PI3K-C2b protein, a member of the PI3 family of kinases, as one of the key regulators of blood vessels growth in humans and other mammals. Mutations in these family of proteins may lead to vascular malformations and the precise understanding of the whole process is instrumental in opening the door to new therapeutic approaches in the future.
Published Researchers decipher enzyme scissors of intestinal microbes
(via sciencedaily.com) Original source Fruit and vegetables contain a variety of plant natural products such as flavonoids, which give fruits their colour and are said to have health-promoting properties. Most plant natural products occur in nature as glycosides, i.e. chemical compounds with sugars. In order for humans to absorb the healthy plant natural products, the sugar must be split off in the intestine. Microorganisms in the intestinal flora help to speed up the process. So-called C-glycosides, i.e. plant natural products with a carbon-based bond to a sugar, would even be practically indigestible without the intestinal microbes (e.g. nothofagin in rooibos tea).
Published Releasing brakes on biocatalysis
(via sciencedaily.com) Original source Enzymes from microorganisms can produce hydrogen (H2) under certain conditions, which makes them potential biocatalysts for biobased H2 technologies. In order to make this hydrogen production efficient, researchers are trying to identify and eliminate possible limiting factors. These include formaldehyde, which occurs naturally as a metabolic product in cells and inhibits the particularly efficient [FeFe] hydrogenase.
Published Building blocks for life could have formed near new stars and planets
(via sciencedaily.com) Original source While life on Earth is relatively new, geologically speaking, the ingredients that combined to form it might be much older than once thought. The simplest amino acid, carbamic acid, could have formed alongside stars or planets within interstellar ices. The findings could be used to train deep space instruments like the James Webb Space Telescope to search for prebiotic molecules in distant, star-forming regions of the universe.
Published The venom preceded the stinger: Genomic studies shed light on the origins of bee venom
(via sciencedaily.com) Original source Bees, wasps and ants belong to the Hymenoptera order and inject a whole cocktail of venomous ingredients when they sting. Despite their tremendous ecological and economic importance, little was previously known about the origins of their venom. Through extensive genomic studies, a team of researchers has now discovered that typical venomous components were already present in the earliest ancestors of Hymenoptera and must therefore have evolved before the stingers of bees and other insects. What's more, and contrary to previous assumptions, the gene for the venom melittin is found solely in bees.
Published Astronomers discover disc around star in another galaxy
(via sciencedaily.com) Original source In a remarkable discovery, astronomers have found a disc around a young star in the Large Magellanic Cloud, a galaxy neighboring ours. It's the first time such a disc, identical to those forming planets in our own Milky Way, has ever been found outside our galaxy. The new observations reveal a massive young star, growing and accreting matter from its surroundings and forming a rotating disc.
Published Tracing the evolution of the 'little brain'
(via sciencedaily.com) Original source The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans. A research team has now generated comprehensive genetic maps of the development of cells in the cerebella of human, mouse and opossum. Comparisons of these maps reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development.
Published Composition of asteroid Phaethon
(via sciencedaily.com) Original source Asteroid Phaethon, which is five kilometers in diameter, has been puzzling researchers for a long time. A comet-like tail is visible for a few days when the asteroid passes closest to the Sun during its orbit. However, the tails of comets are usually formed by vaporizing ice and carbon dioxide, which cannot explain this tail. The tail should be visible at Jupiter's distance from the Sun.
Published Scientists harness flower 'super power' to pave the way for new drug treatments
(via sciencedaily.com) Original source Researchers have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells.
Published A gamma-ray pulsar milestone inspires innovative astrophysics and applications
(via sciencedaily.com) Original source Scientists have announced the discovery of nearly 300 gamma ray pulsars.
Published Solar activity likely to peak next year
(via sciencedaily.com) Original source Researchers have discovered a new relationship between the Sun's magnetic field and its sunspot cycle, that can help predict when the peak in solar activity will occur. Their work indicates that the maximum intensity of solar cycle 25, the ongoing sunspot cycle, is imminent and likely to occur within a year.
Published New way of searching for dark matter
(via sciencedaily.com) Original source Wondering whether whether Dark Matter particles actually are produced inside a jet of standard model particles, led researchers to explore a new detector signature known as semi-visible jets, which scientists never looked at before.
Published Alien haze, cooked in a lab, clears view to distant water worlds
(via sciencedaily.com) Original source Scientists have simulated conditions that allow hazy skies to form in water-rich exoplanets, a crucial step in determining how haziness muddles important telescope observations for the search of habitable worlds beyond the solar system.
Published Study provides fresh insights into antibiotic resistance, fitness landscapes
(via sciencedaily.com) Original source A new study suggests that E. coli bacteria may have a higher capability to evolve antibiotic resistance than previously believed. Researchers mapped possible mutations in an essential E. coli protein involved in antibiotic resistance and found that 75% of evolutionary paths led to high antibiotic resistance, challenging existing theories about fitness landscapes in evolutionary biology. This discovery may have broader implications for understanding adaptation and evolution in various fields.
Published Telescope Array detects second highest-energy cosmic ray ever
(via sciencedaily.com) Original source In 1991, an experiment detected the highest-energy cosmic ray ever observed. Later dubbed the Oh-My-God particle, the cosmic ray’s energy shocked astrophysicists. Nothing in our galaxy had the power to produce it, and the particle had more energy than was theoretically possible for cosmic rays traveling to Earth from other galaxies. Simply put, the particle should not exist. On May 27, 2021, the Telescope Array experiment detected the second-highest extreme-energy cosmic ray. The newly dubbed Amaterasu particle deepens the mystery of the origin, propagation and particle physics of rare, ultra-high-energy cosmic rays.
Published Nutrient found in beef and dairy improves immune response to cancer
(via sciencedaily.com) Original source Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study.
Published Team discovers rules for breaking into Pseudomonas
(via sciencedaily.com) Original source Researchers report that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that -- once it infects a person -- is notoriously difficult to treat.
Published NASA's Webb reveals new features in heart of Milky Way
(via sciencedaily.com) Original source The latest image from NASA's James Webb Space Telescope shows a portion of the dense center of our galaxy in unprecedented detail, including never-before-seen features astronomers have yet to explain. The star-forming region, named Sagittarius C (Sgr C), is about 300 light-years from the Milky Way's central supermassive black hole, Sagittarius A*.
Published A stronger core for better plant breeding
(via sciencedaily.com) Original source A new software tool with enhanced genome-sequencing powers has been developed, increasing the speed and accuracy at which researchers can improve plants through breeding.
Published Tiny beads preserve enzymes for biocatalysis
(via sciencedaily.com) Original source Some enzymes, such as the one derived from fungi and investigated in this study, are able to produce valuable substances such as the fragrance (R)-1-phenylethanol. To this end, they convert a less expensive substrate using a co-substrate. A research team came up with the idea of supplying them with this co-substrate using a plasma -- a somewhat crazy idea, as plasmas generally have a destructive effect on biomolecules. However, by employing several tricks, the researchers did indeed succeed. They have now refined one of these tricks and thus improved the process: They attach the enzymes to tiny beads in order to hold them in place at the bottom of the reactor, where they are protected from the damaging effects of the plasma.