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Categories: Archaeology: General, Biology: Genetics
Published Exercising during pregnancy normalizes eating behaviors in offspring from obese mice



Maternal obesity impacts the eating behaviors of offspring via long-term overexpression of the microRNA miR-505-5p, according to a new study.
Published Key nutrients help plants beat the heat



Scientists have discovered some of the molecular mechanisms controlling how plants -- including important crops like soybean and rice -- will respond to rising global temperatures, finding higher temperatures make root systems grow faster, but sustaining this increased growth speed depends on high levels of nitrogen and phosphorus in the soil. The discoveries point to the necessity of nitrogen and phosphorus-rich soil to promote crop growth and create nutritious crops, in addition to aiding a mission to create more resilient crops in the face of climate change.
Published Crucial shift in River Nile's evolution during ancient Egypt discovered



Researchers have explored how the River Nile evolved over the past 11,500 years and how changes in its geography could have helped shape the fortunes of ancient Egyptian civilization. Research reveals a major shift in the Nile around four thousand years ago, after which the floodplain in the Nile Valley around Luxor greatly expanded.
Published Kinship and ancestry of the Celts in Baden-Württemberg, Germany



The Celtic culture of the pre-Roman Iron Age in Western and Central Europe has left numerous traces to this day, not least in the form of enormous burial mounds and spectacular archaeological artifacts. Despite this rich legacy, much about this civilization remains hidden from us.
Published Paving the way for hydrogen from algae enzymes



Under certain conditions, some algae are able to produce hydrogen -- a much sought-after green energy source. Its production takes place in the unique catalytic center of the unicellular algae and is only possible if certain cofactors of the relevant proteins are present. Researchers have identified how such a cofactor, the so-called hydrogen cluster, is assembled. Specifically, they describe the previously unexplained role of the enzyme HydF, which is involved in the final steps of assembly.
Published Researchers discover 'trojan horse' virus hiding in human parasite



An international team has found a new RNA virus that they believe is hitching a ride with a common human parasite. The virus is associated with severe inflammation in humans infected with the parasite Toxoplasma gondii, leading the team to hypothesize that it exacerbates toxoplasmosis disease.
Published Could the world famous Roman Baths help scientists counter the challenge of antibiotic resistance?



A new study has uncovered a diverse array of microorganisms within the hot waters of the Roman Baths, regularly listed among the UK's most popular tourist attractions. Tests showed 15 of the isolated bacteria -- including examples of Proteobacteria and Firmicutes -- displayed varying levels of inhibition against human pathogens including E.coli, Staphylococcus Aureus and Shigella flexneri.
Published The world's most powerful anti-fungal chemistries cause fungal pathogens to self-destruct



Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.
Published New, modified CRISPR protein can fit inside virus used for gene therapy



Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.
Published Researchers expose new symbiosis origin theories, identify experimental systems for plant life



Research work on symbiosis -- a mutually beneficial relationship between living organisms -- is pushing back against the newer theory of a 'single-origin' of root nodule symbiosis (RNS) -- that all symbiosis between plant root nodules and nitrogen-fixing bacteria stems from one point--instead suggesting a 'multiple-origin' theory of sybiosis which opens a better understanding for genetically engineering crops.
Published Researchers apply quantum computing methods to protein structure prediction



Researchers recently published findings that could lay the groundwork for applying quantum computing methods to protein structure prediction.
Published hnRNPM, a guardian of the integrity of cellular protein production



Researchers have discovered that the protein hnRNPM prevents the cell from making mistakes while it is producing new proteins, which helps maintain the integrity of this vital process.
Published Editing without 'cutting': Molecular mechanisms of new gene-editing tool revealed



New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime editor' could achieve reverse transcription, synthesizing DNA from RNA, without 'cutting' both strands of the double helix. Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.
Published Chicken feathers to deliver chemotherapy drugs and repair enzymes



A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.
Published Complete X and Y chromosome sequences of living great ape species determined



Newly generated, complete genomes for the sex chromosomes of six primate species may inform conservation of these endangered species and shed light on sex-related genetic diseases in both humans and our closest living relatives.
Published Scientists identify gene that could lead to resilient 'pixie' corn



A widely found gene in plants has been newly identified as a key transporter of a hormone that influences the size of corn. The discovery offers plant breeders a new tool to develop desirable dwarf varieties that could enhance the crop's resilience and profitability.
Published Bringing back an ancient bird



Using ancient DNA extracted from the toe bone of a museum specimen, biologists have sequenced the genome of an extinct, flightless bird called the little bush moa, shedding light into an unknown corner of avian genetic history. The work is the first complete genetic map of the turkey-sized bird whose distant living cousins include the ostrich, emu, and kiwi.
Published Mechanisms for selective multiple sclerosis treatment strategy



Researchers have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.
Published 'Cloaked' proteins deliver cancer-killing therapeutics into cells



Scientists have designed a way to 'cloak' proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.
Published Genetic mosaicism more common than thought



Researchers found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations without causing any apparent disease or abnormality. Even so-called normal cells carry all sorts of genetic mutations, meaning there are more genetic differences between individual cells in our bodies than between different human beings. The discovery was enabled by a single-cell sequencing technology called Strand-seq, a unique DNA sequencing technique that can reveal subtle details of genomes in single cells that are too difficult to detect with other methods.