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Categories: Archaeology: General, Biology: Genetics
Published Ancient retroviruses played a key role in the evolution of vertebrate brains
(via sciencedaily.com) Original source Researchers report that ancient viruses may be to thank for myelin -- and, by extension, our large, complex brains. The team found that a retrovirus-derived genetic element or 'retrotransposon' is essential for myelin production in mammals, amphibians, and fish. The gene sequence, which they dubbed 'RetroMyelin,' is likely a result of ancient viral infection, and comparisons of RetroMyelin in mammals, amphibians, and fish suggest that retroviral infection and genome-invasion events occurred separately in each of these groups.
Published Anthropologists' research unveils early stone plaza in the Andes
(via sciencedaily.com) Original source Located at the Callacpuma archaeological site in the Cajamarca Basin of northern Peru, the plaza is built with large, vertically placed megalithic stones -- a construction method previously unseen in the Andes.
Published Team creates novel rabies viral vectors for neural circuit mapping
(via sciencedaily.com) Original source A research team has created 20 new recombinant rabies viral vectors for neural circuit mapping that offer a range of significant advantages over existing tools, including the ability to detect microstructural changes in models of aging and Alzheimer's disease brain neurons.
Published Key genes linked to DNA damage and human disease uncovered
(via sciencedaily.com) Original source Scientists unveil 145 genes vital for genome health, and possible strategies to curb progression of human genomic disorders.
Published Some Pre-Roman humans were buried with dogs, horses and other animals
(via sciencedaily.com) Original source Some people from an ancient community in what is now northern Italy were interred with animals and animal parts from species such as dogs, horses and pigs. The reasons remain mysterious, but might indicate an enduring companion relationship between these humans and animals, or religious sacrificial practices, according to a new study.
Published Researchers uncover mechanisms behind enigmatic shapes of nuclei
(via sciencedaily.com) Original source White blood cells known as neutrophils feature a nucleus that is structured strikingly different than most nuclei. These unique shapes permit neutrophils to travel all over the body to combat invading pathogens. Scientists have now deciphered the shapeshifting puzzle of the neutrophil nucleus.
Published New understanding of avian eggshell attachment -- implications for medical procedures and egg industry
(via sciencedaily.com) Original source Athletes often suffer injuries to ligaments in their knees, particularly to the anterior cruciate ligament or ACL. While surgery to replace these torn ligaments is becoming increasingly common around the world it often needs to be repeated. That's because it has proved challenging to anchor fibrous, soft and wet ligament grafting material into hard bone. Now, researchers have new information from the eggshell membrane in chicken eggs that could help change this picture thanks to the potential it offers for improvements in tissue engineering and biomaterial grafts. Their findings also have the potential to reduce losses for commercial egg and poultry producers.
Published By growing animal cells in rice grains, scientists dish up hybrid food
(via sciencedaily.com) Original source From lab-grown chicken to cricket-derived protein, these innovative alternatives offer hope for a planet struggling with the environmental and ethical impacts of industrial agriculture. Now, scientists add a new recipe to the list -- cultured beef rice -- by growing animal muscle and fat cells inside rice grains. The method results in a nutritious and flavorful hybrid food that, once commercialized, could offer a more affordable protein alternative with a smaller carbon footprint.
Published Controlling root growth direction could help save crops and mitigate climate change
(via sciencedaily.com) Original source Scientists have determined how the well-known plant hormone ethylene is crucial in controlling the angle at which roots grow. The findings can be used to engineer plants and crops that withstand the environmental stresses of climate change and drought, and perhaps to create plants that remove carbon dioxide from the atmosphere and store it deep underground to help mitigate climate change.
Published CRISPR-copies: New tool accelerates and optimizes genome editing
(via sciencedaily.com) Original source Researchers are further improving CRISPR's versatility to engineer new grasses and yeasts for biochemical production.
Published Low-cost microbe can speed biological discovery
(via sciencedaily.com) Original source Researchers have created a new version of a microbe to compete economically with E. coli -- a bacteria commonly used as a research tool due to its ability to synthesize proteins -- to conduct low-cost and scalable synthetic biological experiments.
Published New trial highlights incremental progress towards a cure for HIV-1
(via sciencedaily.com) Original source A new clinical trial suggests that a combination of the drug vorinostat and immunotherapy can coax HIV-infected cells out of latency and attack them. The findings highlight how close -- yet still far -- researchers have come to developing a cure for HIV-1.
Published Archaeologists discover oldest known bead in the Americas
(via sciencedaily.com) Original source The bead found at the La Prele Mammoth site in Wyoming's Converse County is about 12,940 years old and made of bone from a hare.
Published Nutrients direct intestinal stem cell function and affect aging
(via sciencedaily.com) Original source The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging. Researchers have discovered a new mechanism of action between the nutrient adaptation of intestinal stem cells and aging. The finding may make a difference when seeking ways to maintain the functional capacity of the aging gut.
Published Researchers uncover genetic factors for severe Lassa fever
(via sciencedaily.com) Original source Researchers report the results of the first ever genome-wide association study (GWAS) of a biosafety level 4 (BSL-4) virus. The team found two key human genetic factors that could help explain why some people develop severe Lassa fever, and a set of LARGE1 variants linked to a reduced chance of getting Lassa fever. The work could lay the foundation for better treatments for Lassa fever and other similar diseases. The scientists are already working on a similar genetics study of Ebola susceptibility.
Published Scandinavia's first farmers slaughtered the hunter-gatherer population, study finds
(via sciencedaily.com) Original source Following the arrival of the first farmers in Scandinavia 5,900 years ago, the hunter-gatherer population was wiped out within a few generations, according to a new study. The results, which are contrary to prevailing opinion, are based on DNA analysis of skeletons and teeth found in what is now Denmark.
Published New research uncovers biological drivers of heart disease risk
(via sciencedaily.com) Original source Over the past 15 years, researchers have identified hundreds of regions in the human genome associated with heart attack risk. However, researchers lack efficient ways to explore how these genetic variants are molecularly connected to cardiovascular disease, limiting efforts to develop therapeutics. To streamline analysis of hundreds of genetic variants associated with coronary artery disease (CAD), a team of researchers combined multiple sequencing and experimental techniques to map the relationship between known CAD variants and the biological pathways they impact.
Published New approach to tackling bacterial infections identified
(via sciencedaily.com) Original source Researchers have identified a new approach to controlling bacterial infections. The team found a way to turn on a vital bacterial defense mechanism to fight and manage bacterial infections. The defense system, called cyclic oligonucleotide-based antiphage signaling system (CBASS), is a natural mechanism used by certain bacteria to protect themselves from viral attacks. Bacteria self-destruct as a means to prevent the spread of virus to other bacterial cells in the population.
Published Researchers discover key to molecular mystery of how plants respond to changing conditions
(via sciencedaily.com) Original source A team of researchers recently published a pioneering study that answers a central question in biology: how do organisms rally a wide range of cellular processes when they encounter a change -- either internally or in the external environment -- to thrive in good times or survive the bad times? The research, focused on plants, identifies the interactions between four compounds: pectin, receptor proteins FERONIA and LLG1 and the signal RALF peptide.
Published Thailand's Iron Age Log Coffin culture
(via sciencedaily.com) Original source A mortuary practice known as Log Coffin culture characterizes the Iron Age of highland Pang Mapha in northwestern Thailand. Between 2,300 and 1,000 years ago, individuals were buried in large wooden coffins on stilts, mostly found in caves and rock shelters.