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Categories: Archaeology: General, Biology: Genetics
Published 200-year-old DNA helps map tiny fly's genetic course to new lands, modern times



Researchers have extracted and analyzed DNA from fruit flies housed in museum collections in Lund, Stockholm and Copenhagen. Surprisingly, the researchers found the fruit flies collected in Sweden in the early 1800s were more genetically similar to 21st century flies than the Swedish samples from the 1930s.
Published Scientists generate first single-cell 'atlas' of the primate brain to help explore links between molecules, cells, brain function and disease



As part of the effort to better understand the evolution of the brains in people and animals, a research team has generated the world's largest primate brain-wide atlas.
Published Scientists unveil detailed cell maps of the human brain and the nonhuman primate brain



A group of international scientists have mapped the genetic, cellular, and structural makeup of the human brain and the nonhuman primate brain. This understanding of brain structure allows for a deeper knowledge of the cellular basis of brain function and dysfunction, helping pave the way for a new generation of precision therapeutics for people with mental disorders and other disorders of the brain.
Published Honey bees may inherit altruistic behavior from their mothers



True altruism is rare behavior in animals, but a new study has found that honey bees display this trait. Additionally, they found that an evolutionary battle of genetics may determine the parent they inherit it from.
Published Win-win in muscle research: Faster results and fewer laboratory animals thanks to new method



To study muscle diseases, scientists rely on the mouse as a model organism. Researchers have now developed a new method that is not only faster and more efficient than conventional ones but also greatly reduces the number of experimental animals needed for studying the function of genes in muscle fibers.
Published Omega-3 discovery moves us closer to 'precision nutrition' for better health



Researchers have obtained new insights into how African-American and Hispanic-American people’s genes influence their ability to use Omega-3 and Omega-6 fatty acids for good health. The findings are an important step toward “precision nutrition” – where a diet tailored to exactly what our bodies need can help us live longer, healthier lives.
Published Doubling down on known protein families



A massive computational analysis of microbiome datasets has more than doubled the number of known protein families. This is the first time protein structures have been used to help characterize the vast array of microbial 'dark matter.'
Published Death is only the beginning: Birds disperse eaten insects' eggs



Relationship patterns among flightless stick insects suggest that birds disperse the eggs after eating gravid females. Lab experiments previously suggested the possibility, but a new genetic analysis of natural populations in Japan now supports the idea.
Published Newfound mechanism suggests drug combination could starve pancreatic cancer



A study found that a new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel.
Published Epigenetic regulator MOF drives mitochondrial metabolism



Researchers have unveiled a new mechanism for regulating mitochondrial function. The findings reveal the critical role played by the enzymatic activity of the lysine acetyltransferase MOF in maintaining mitochondrial integrity and function through acetylation of mitochondrial electron transport chain component COX17. Cells lacking MOF-mediated COX17 acetylation exhibit dramatic mitochondrial defects and impaired ability to produce energy. Underscoring the clinical relevance of these findings, the team also showed that cells from human patients with a developmental disorder caused by mutations in MOF also exhibited respiratory defects that could be ameliorated by interventions such as acetylation-mimetic COX17 or mitochondrially targeted MOF.
Published How male mosquitoes compensate for having only one X chromosome


Researchers have discovered the master regulator responsible for balancing the expression of X chromosome genes between males and females in the malaria mosquito. This discovery helps scientists better understand the evolution of the epigenetic mechanisms responsible for equalizing gene expression between the sexes. The findings may contribute to the development of new ways to prevent the spread of malaria.
Published Natural GM crops: Grasses take evolutionary shortcut by borrowing genes from their neighbors



Grass may transfer genes from their neighbors in the same way genetically modified crops are made, a new study has revealed.
Published New discovery may 'unlock' the future of infectious disease and cancer treatment



Researchers have identified a 'guard mechanism' for a protein which attacks microbes in infected cells, opening the possibility of new treatments for Toxoplasma, Chlamydia, Tuberculosis and even cancer.
Published The end of genes: Routine test reveals unique divergence in genetic code



Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics. The genome of a protist has revealed a seemingly unique divergence in the DNA code signalling the end of a gene, suggesting the need for further research to better understand this group of diverse organisms.
Published New open-source method to improve decoding of single-cell data



Researchers have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data. By guiding data analysis in a unique way, Spectra can offer new insights into the complex interplay between cells — like the interactions between cancer cells and immune cells, which are critical to improving immunotherapy treatments.
Published Ruffed grouse population more resilient than expected, genetic study finds



Despite decades of decline, a genetic analysis of ruffed grouse reveals that Pennsylvania's state bird harbors more genetic diversity and connectivity than expected. The findings suggest that the iconic game bird could be maintained in persistent numbers if appropriate protections are implemented.
Published Being a vegetarian may be partly in your genes



A person's genetic makeup plays a role in determining whether they can stick to a strict vegetarian diet, a new study has found. The findings open the door to further studies that could have important implications regarding dietary recommendations and the production of meat substitutes.
Published Proteins roll the dice to determine bee sex



To date it has been unclear exactly how the sex of a bee is determined. A research team comprising biologists and chemists has now identified a key gene and the molecular mechanism linked with it. They describe how this process is similar to a game involving two dice.
Published Avatars to help tailor glioblastoma therapies



Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study.
Published Honeybees are more selective in their choices for nutrition than previously thought



An international research group examined which plants honeybees favor when collecting nectar and pollen. The choices honeybees make have an impact on their health and also on humans, as honeybees pollinate important crop plants.