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Categories: Biology: Genetics, Paleontology: General
Published Wisconsin cave holds tantalizing clues to ancient climate changes, future shifts


A newly published study of a stalagmite found in Cave of the Mounds reveals previously undetected history of the local climate going back thousands of years. Researchers describe evidence for an ice age punctuated by massive and abrupt warming events across much of the Northern Hemisphere.
Published Researchers provide proof of the helical coiling of condensed chromosomes



In early cytological studies chromatids of metaphase chromosomes were suggested to coil into a spiral called chromonema. This assumption was recently supported by chromosomce conformation capture sequencing. Still, the direct visualization of the coiled chromonema confirming the helical model was lacking. Now, an international research team provides the direct proof of the helical coiling of condensed chromatids via super-resolution microscopy of specifically labelled chromonema regions.
Published Waxing and waning of environment influences hominin dispersals across ancient Iran


A world-first model of paleoclimate and hydrology in Iran has highlighted favourable routes for Neanderthals and modern human expansions eastwards into Asia. The findings reveal that multiple humid periods in ancient Iran led to the expansions of human populations, opening dispersal route across the region, and the possible interactions of species such as Neanderthals and our own Homo sapiens.
Published Prehistoric sea monster may have been shorter, stouter, than once believed


A big fish story? Maybe so: The greatest sea monster of the Devonian Period (Dunkleosteus terrelli) may be getting downsized. A new article contents that the famous sea monster of the Age of Fishes may not have neared 30-feet in length, as long believed, but topped off at maybe 13 feet. The new assertion brings attention to a famously fierce looking armored fish from 360 million years ago -- and maybe a new debate.
Published New study unveils epigenetic 'traffic lights' controlling stop and go for gene activity


A major new study reveals a 'traffic light' mechanism controlling genetic activity within cells -- a system which could potentially be targeted by cancer drugs already in development. The research describes how 'epigenetic' changes to the structure of DNA can act as a stop-go signal in determining whether a gene should be read. Unlike our genetic make-up, which is well understood, the world of epigenetics is still largely unexplored and referred to as the 'dark matter' of the genome.
Published Mapping unknown territory


A detailed atlas of gene expression in the zebrafish brain.
Published Jurassic shark: Shark from the Jurassic period was already highly evolved


Cartilaginous fish have changed much more in the course of their evolutionary history than previously believed. Evidence for this thesis has been provided by new fossils of a ray-like shark, Protospinax annectans, which demonstrate that sharks were already highly evolved in the Late Jurassic.
Published Dinosaur claws used for digging and display


Dinosaur claws had many functions, but now a team has shown some predatory dinosaurs used their claws for digging or even for display.
Published Evolutionary history of detoxifying enzymes reconstructed


Biochemists have succeeded in resurrecting the ancestral genes of five detoxifying enzymes which are present in all tetrapods to show how their divergence in function has occurred.
Published Ancient proteins offer new clues about origin of life on Earth



By simulating early Earth conditions in the lab, researchers have found that without specific amino acids, ancient proteins would not have known how to evolve into everything alive on the planet today -- including plants, animals, and humans.
Published Cells avoid multitasking


Textbooks will tell you that in dividing cells, production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level. Molecular biologists have now discovered that this is not true: protein synthesis shows two peaks and lipid synthesis peaks once.
Published Successful cure of HIV infection after stem cell transplantation, study suggests


Haematopoietic stem cell transplantation for the treatment of severe blood cancers is the only medical intervention that has cured two people living with HIV in the past. An international group of physicians and researchers has now identified another case in which HIV infection has been shown to be cured in the same way. The successful healing process of this third patient was for the first time characterized in great detail virologically and immunologically over a time span of ten years.
Published Clues about the Northeast's past and future climate from plant fossils


A team of researchers is working to understand the details of the climate for the eastern portion of the United States from the Miocene, which unfortunately is a blank spot on paleo-climate maps. New findings suggest the future climate will be very close to the warmer, wetter, and more homogeneous climate similar to conditions experienced 5 million years ago.
Published The achilles heel of the influenza virus: Ubiquitin protein may be an approach for future medicines



Influenza viruses are becoming increasingly resilient to medicines. For this reason, new active ingredients are needed. Important findings in this regard have been provided: for the virus to proliferate, the polymerase of the influenza A virus has to be modified many times through enzymes in the host cells. The team of researchers was able to produce a comprehensive map of types of modification. Medicines directed against the enzymes woud be resilient to rapid mutations in the virus, thus offering great potential for the future.
Published Insect bite marks show first fossil evidence for plants' leaves folding up at night


Plants can move in ways that might surprise you. Some of them even show 'sleep movements,' folding or raising their leaves each night before opening them again the next day. Now, researchers offer convincing evidence for these nightly movements, also known as foliar nyctinasty, in fossil plants that lived more than 250 million years ago.
Published Making engineered cells dance to ultrasound


A team has developed a method for selectively manipulating genetically engineered cells with ultrasound.
Published Scientists unlock key to drought-resistant wheat plants with longer roots


Growing wheat in drought conditions may be easier in the future. Researchers found the right number of copies of a specific group of genes can stimulate longer root growth, enabling wheat plants to pull water from deeper supplies.
Published Evolution of dinosaur body size through different developmental mechanisms


The meat-eating dinosaurs known as theropods that roamed the ancient Earth ranged in size from the bus-sized T. rex to the smaller, dog-sized Velociraptor. Scientists puzzling over how such wildly different dinosaur sizes evolved recently found -- to their surprise -- that smaller and larger theropod dinosaurs like these didn't necessarily get that way merely by growing slower or faster.
Published Psyllium fiber protects against colitis by activating bile acid sensor, biomedical sciences researchers find



Psyllium fiber protects against ulcerative colitis and suppresses inflammation by activating the bile acid nuclear receptor, a mechanism that was previously unrecognized, according to a new study.
Published MoBIE enables modern microscopy with massive data sets


High-resolution microscopy techniques, for example electron microscopy or super-resolution microscopy, produce huge amounts of data. The visualization, analysis and dissemination of such large imaging data sets poses significant challenges. Now, these tasks can be carried out using MoBIE, which stands for Multimodal Big Image Data Exploration, a new user-friendly, freely available tool. This means that researchers such as biologists, who rely on high-resolution microscopy techniques, can incorporate multiple data sets to study the processes of life at the very smallest scales.