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Categories: Biology: Genetics, Paleontology: General
Published Humans' ancestors survived the asteroid impact that killed the dinosaurs
(via sciencedaily.com) Original source A Cretaceous origin for placental mammals, the group that includes humans, dogs and bats, has been revealed by in-depth analysis of the fossil record, showing they co-existed with dinosaurs for a short time before the dinosaurs went extinct.
Published Researchers develop digital test to directly measure HIV viral load
(via sciencedaily.com) Original source A milliliter of blood contains about 15 individual drops. For a person with human immunodeficiency virus (HIV), each drop of blood could contain anywhere from fewer than 20 copies of the virus to more than 500,000 copies. Called the viral load, this is what is measured to allow clinicians to understand how patients are responding to anti-viral medications and monitor potential progression. The time-consuming viral load testing needs to be repeated several times as a patient undergoes treatment. Now, a research team has developed a time and cost-efficient digital assay that can directly measure the presence of HIV in single drop of blood.
Published 50-million-year-old katydid fossil reveals muscles, digestive tract, glands and a testicle
(via sciencedaily.com) Original source 50 million years ago in what is now northwestern Colorado, a katydid died, sank to the bottom of a lake and was quickly buried in fine sediments, where it remained until its compressed fossil was recovered in recent years. When researchers examined the fossil under a microscope, they saw that not only had many of the insect's hard structures been preserved in the compressed shale, so had several internal organs and tissues, which are not normally fossilized.
Published Megalodon was no cold-blooded killer
(via sciencedaily.com) Original source How the megalodon, a shark that went extinct 3.6 million years ago, stayed warm was a matter of speculation among scientists. Using an analysis of tooth fossils from the megalodon and other sharks of the same period, a study suggests the animal was able to maintain a body temperature well above the temperature of the water in which it lived. The finding could help explain why the megalodon went extinct during the Pliocene Epoch.
Published How coral reefs can survive climate change
(via sciencedaily.com) Original source Similar to the expeditions of a hundred or two hundred years ago, the Tara Pacific expedition lasted over two years. The goal: to research the conditions for life and survival of corals. The ship crossed the entire Pacific Ocean, assembling the largest genetic inventory conducted in any marine system to date. The team's 70 scientists from eight countries took around 58,000 samples from the hundred coral reefs studied.
Published Humans' evolutionary relatives butchered one another 1.45 million years ago
(via sciencedaily.com) Original source Researchers have identified the oldest decisive evidence of humans' close evolutionary relatives butchering and likely eating one another.
Published Extinct warbler's genome sequenced from museum specimens
(via sciencedaily.com) Original source The Bachman's warbler, a songbird that was last seen in North America nearly 40 years ago, was a distinct species and not a hybrid of its two living sister species, according a new study in which the full genomes of seven museum specimens of the bird were sequenced.
Published Drug decelerates bacterial race to antibiotic resistance
(via sciencedaily.com) Original source Researchers report that, in laboratory cultures and animal models, a drug significantly reduces the ability of bacteria to develop antibiotic resistance, which might prolong antibiotic effectiveness.
Published Researcher uses pressure to understand RNA dynamics
(via sciencedaily.com) Original source Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Scientists are studying the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.
Published The molecular control center of our protein factories
(via sciencedaily.com) Original source Researchers have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in protein sorting.
Published The clue is in the glue -- Nature's secret for holding it together
(via sciencedaily.com) Original source An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.
Published A roadmap for gene regulation in plants
(via sciencedaily.com) Original source For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant's physiological traits. Their work reveals unprecedented insights into gene regulatory networks and identifies a new library of DNA parts that can be used to optimize plants for bioenergy and agriculture.
Published Cave excavation pushes back the clock on early human migration to Laos
(via sciencedaily.com) Original source Fifteen years of archaeological work in the Tam Pa Ling cave in northeastern Laos has yielded a reliable chronology of early human occupation of the site. The team's excavations through the layers of sediments and bones that gradually washed into the cave and were left untouched for tens of thousands of years reveals that humans lived in the area for at least 70,000 years -- and likely even longer.
Published Now, every biologist can use machine learning
(via sciencedaily.com) Original source Scientists have built a new, comprehensive AutoML platform designed for biologists with little to no ML experience. New automated machine learning platform enables easy, all-in-one analysis, design, and interpretation of biological sequences with minimal coding. Their platform, called BioAutoMATED, can use sequences of nucleic acids, peptides, or glycans as input data, and its performance is comparable to other AutoML platforms while requiring minimal user input.
Published DNA can fold into complex shapes to execute new functions
(via sciencedaily.com) Original source DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study.
Published Plant extracts used by indigenous people hold promise in treatment of ataxia
(via sciencedaily.com) Original source Researchers have discovered that extracts from plants used by the Kwakwaka'wakw First Nations peoples in their traditional botanical medicine practices are able to rescue the function of ion channel proteins carrying mutations that cause human Episodic Ataxia.
Published Researchers reveal mechanism of protection against breast and ovarian cancer
(via sciencedaily.com) Original source Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer.
Published Modern horses have lost their additional toes, scientists confirm
(via sciencedaily.com) Original source The distant ancestors of modern horses had hooved toes instead of a single hoof, which vanished over time, according to researchers.
Published Scientists discover new embryonic cell type that self-destructs to protect the developing embryo
(via sciencedaily.com) Original source Scientists have uncovered a new quality control system that removes damaged cells from early developing embryos.
Published Completing genome of rusty patched bumble bee may offer new approach to saving endangered bee
(via sciencedaily.com) Original source A detailed, high-resolution map of the rusty patched bumble bee's genome has been released, offering new approaches for bringing the native pollinator back from the danger of extinction. Putting together the rusty patched bumble bee genome is part of the Beenome 100 project, a first-of-its-kind effort to create a library of high-quality, highly detailed genome maps of 100 or more diverse bee species found in the United States.