Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Marine Biology: Microbiology Ecology: Sea Life
Published

Rediscovery of rare marine amoeba Rhabdamoeba marina      (via sciencedaily.com)     Original source 

Researchers have rediscovered and successfully cultivating Rhabdamoeba marina -- a rare marine amoeba that has only been reported in two cases in the past century. Using this culture strain, they performed a comprehensive analysis of its genetic sequence, revealing for the first time the phylogenetic position of this enigmatic amoeba, and proposed a novel taxonomic classification based on their research findings.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Genomic tug of war could boost cancer therapy      (via sciencedaily.com)     Original source 

Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic syndromes that is plagued by drug resistance issues. For the first time, researchers show that decitabine causes coding and non-coding regions of DNA to engage in a tug of war for a gene activator, called H2A.Z. Typically, deticabine draws this gene activator away from coding DNA, causing gene expression to grind to a halt and cells to die. However, many types of cancer have very high levels of H2A.Z, which may help them overcome this decitabine-induced tug of war, allowing the cancer to grow.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

How cell identity is preserved when cells divide      (via sciencedaily.com)     Original source 

A new theoretical model helps explain how epigenetic memories, encoded in chemical modifications of chromatin, are passed from generation to generation.  Within each cell's nucleus, researchers suggest, the 3D folding patterns of its genome determines which parts of the genome will be marked by these chemical modifications.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Marine Biology: Microbiology Biology: Molecular Environmental: Ecosystems Environmental: General Geoscience: Environmental Issues Offbeat: Earth and Climate Offbeat: General Offbeat: Plants and Animals
Published

Much more than waste: Tiny vesicles exchange genetic information between cells in the sea      (via sciencedaily.com)     Original source 

Researchers take a look at data that has so far been mostly discarded as contamination, revealing the previously underestimated role of extracellular vesicles (EVs). These are important for the exchange of genetic information between cells and thus for the microbial community in the sea.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Hormones have the potential to treat liver fibrosis      (via sciencedaily.com)     Original source 

Researchers have discovered previously unknown changes in a specific type of liver cells, potentially opening avenues for a new treatment for liver fibrosis, a potentially life-threatening condition. Currently, there are no drugs available to treat liver fibrosis.

Biology: Zoology Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals Paleontology: Early Mammals and Birds Paleontology: Fossils Paleontology: General
Published

Birds set foot near South Pole in Early Cretaceous, Australian tracks show      (via sciencedaily.com)     Original source 

The discovery of 27 avian footprints on the southern Australia coast -- dating back to the Early Cretaceous when Australia was still connected to Antarctica -- opens another window onto early avian evolution and possible migratory behavior.

Biology: Botany Biology: General Biology: Microbiology Ecology: Endangered Species Ecology: Extinction Ecology: Nature Ecology: Research Paleontology: Climate Paleontology: Early Mammals and Birds Paleontology: Fossils Paleontology: General
Published

Plants that survived dinosaur extinction pulled nitrogen from air      (via sciencedaily.com)     Original source 

Ancient cycad lineages that survived the extinction of the dinosaurs may have done so by relying on symbiotic bacteria in their roots to fix atmospheric nitrogen. The finding came from an effort to understand ancient atmospheres, but became an insight into plant evolution instead.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

How bacteria recognize viral invasion and activate immune defenses      (via sciencedaily.com)     Original source 

Bacteria have an array of strategies to counter viral invasion, but how they first spot a stranger in their midst has long been a mystery.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Geoscience: Geochemistry
Published

Unexpected discovery opens bioengineering opportunities for human and plant health      (via sciencedaily.com)     Original source 

An unexpected genetic discovery in wheat has led to opportunities for metabolic engineering of versatile compounds with potential to improve its nutritional qualities and resilience to disease.

Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Ecology: Endangered Species
Published

Genetic discovery promises high-iron vegetables and cereals      (via sciencedaily.com)     Original source 

A genetic breakthrough has opened new opportunities for iron-fortified vegetables and cereal crops to help address the global health issue of anemia.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Novel C. diff structures are required for infection, offer new therapeutic targets      (via sciencedaily.com)     Original source 

Newly discovered iron storage 'ferrosomes' inside the bacterium C. diff -- the leading cause of hospital-acquired infections -- are important for infection in an animal model and could offer new targets for antibacterial drugs. They also represent a rare demonstration of a membrane-bound structure inside a pathogenic bacterium, upsetting the biological dogma that bacteria do not contain organelles. 

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular Ecology: Endangered Species
Published

A tale of two proteins: Fundamental research could make growing better crops like clockwork      (via sciencedaily.com)     Original source 

Rhomboid-like protein 10, or RBL10, is thought to be an enzyme that degrades other proteins in the chloroplast membrane, but its function is largely unknown. Researchers are studying how RBL10 affects photosynthetic membrane lipid metabolism, an essential process in photosynthesis.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

How marine bristle worms use a special protein to distinguish between sunlight and moonlight      (via sciencedaily.com)     Original source 

A research team has presented its findings on the functioning of an atypical cryptochrome protein (Cry). These proteins are found in a variety of organisms, and they are often involved in light-controlled biological processes. The marine bristle worm Platynereis dumerilii, for example, employs a special Cry protein designated L-Cry to distinguish between sunlight and moonlight as well as between different moon phases. This is essential for the worms to synchronize their reproduction to the full moon phase via an inner monthly calendar, also called circalunar clock.

Biology: Biochemistry Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

New drug-like molecule extends lifespan, ameliorates pathology in worms and boosts function in mammalian muscle cells      (via sciencedaily.com)     Original source 

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.  Researchers have identified a new drug-like molecule that keeps mitochondria healthy via mitophagy, a process that removes and recycles damaged mitochondria in multicellular organisms. The compound, dubbed MIC, is a natural compound that extended lifespan in C. elegans, ameliorated pathology in neurodegenerative disease models of C. elegans, and improved mitochondrial function in mouse muscle cells.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Yeast cells can produce drugs for treatment of psychotic disorders      (via sciencedaily.com)     Original source 

An international team of researchers has demonstrated that genetically engineered yeast cells can produce the natural plant product alstonine, which has shown positive effects in treating schizophrenia.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Team creates synthetic enzymes to unravel molecular mysteries      (via sciencedaily.com)     Original source 

A bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos. The team of researchers is using a new approach, called the Synthetic Processing (SynPro) system, in zebrafish to study how Vg1 is formed. By learning the molecular rules of signal formation in a developing animal, researchers aim to engineer mechanisms -- such as giving cells new instructions -- that could play a role in treating or preventing disease.