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Categories: Biology: Genetics, Paleontology: Early Mammals and Birds
Published These worms have rhythm
(via sciencedaily.com) Original source Researchers have developed a new imaging technique to observe active gene expression in real time. They found that four molecules work together to control the timing of each stage of the C. elegans worm's development. This timekeeping process could provide important clues about the natural rhythm of development in humans and other animals.
Published Dog diversity unveiled by international DNA database
(via sciencedaily.com) Original source An international consortium of scientists is using an unprecedentedly large database of canine DNA to take an unbiased look at how our furry friends evolved into the various breeds we know and love.
Published Blood-brain barrier governs ant behavior by altering hormone levels
(via sciencedaily.com) Original source In many animals, including ants, the blood-brain barrier (BBB) ensures normal brain function by controlling the movement of various substances in and out of the brain. Now, researchers have made the unexpected discovery that the BBB in carpenter ants plays an active role in controlling behavior that's essential to the function of entire ant colonies. The key is production in the BBB of a particular hormone-degrading enzyme.
Published Engineers design more powerful RNA vaccines
(via sciencedaily.com) By adding synergistic self-adjuvanting properties to COVID-19 RNA vaccines, researchers showed they could significantly boost the immune response generated in mice.
Published Genetic tools probe microbial dark matter
(via sciencedaily.com) Original source Genetic manipulation of a puzzling, miniscule bacteria that has lived in human mouths at least since the Middle Stone Age is elucidating the genes needed for its unusual lifestyle. These Patescibacteria in the human oral microbiome reside on the surface of another, larger host microbe. Found in many water and land environments, Patescibacteria in general lack the genes required to make many molecules necessary for life, such as the amino acids that make up proteins, the fatty acids that form membranes, and the nucleotides in DNA. This has led researchers to speculate that many of them rely on other bacteria to grow. In a new study, researchers present the first glimpse into the molecular mechanisms behind their relationship with their host cells. They also share details gleaned from fluorescent, time-lapse microsopic imaging of these bacteria as they bud and send out swarms of tiny progeny, only a fraction of which are able to establish a host relationship.
Published Cattle on low-protein rations may need amino acid supplement to boost milk yield
(via sciencedaily.com) Original source When dairy cows are fed diets with reduced protein concentrations -- aimed at decreased environmental nitrogen pollution from their manure such as nitrate leaching, nutrient-laden run-off and ammonia volatilization -- their milk production can suffer. Supplementing the amino acid histidine may help in maintaining, and even increasing, milk and milk-protein yields.
Published Keeping herpes in check
(via sciencedaily.com) Original source Herpes is not only unpleasant but it can, in some cases, also have dangerous complications and life-threatening consequences. A research team has now introduced a completely new approach for treating herpes. Their method is based on the inhibition of an enzyme that is needed for the release of newly formed virus particles from infected cells.
Published Study illuminates mechanism that annotates genetic information passed from fathers to offspring
(via sciencedaily.com) Original source Scientists have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring. The findings shed new light on genomic imprinting, a fundamental, biological process in which a gene from one parent is switched off while the copy from the other parent remains active. Errors in imprinting are linked to a host of diseases, such as the rare disease Silver-Russell syndrome along with certain cancers and diabetes.
Published How does the social behavior of wheat plants influence grain production?
(via sciencedaily.com) Original source Researchers have investigated how the behavior of an individual wheat plant under limiting light conditions influences the performance of the whole community. They assessed morphological and biomass phenotypes of single plants grown in mixtures under sunlight and a simulated canopy shade, and the relevance of these phenotypes for the monoculture community in the field.
Published Unveiling the mechanism of 3D folding of cell sheets
(via sciencedaily.com) Original source A team of researchers has revealed that the Dumpy protein, a component of extracellular matrices -- or ECM -- is the key factor in regulating the stereotypic origami-like folding of wing-cell sheets. Their findings that wing cells never divide during folding nor do they exhibit spatially distinct behaviors suggest how external cues can create consistent 3D tissue structures.
Published Switching from harmful to helpful fungi
(via sciencedaily.com) Original source Mold and diseases caused by fungi can greatly impact the shelf life of fruit and vegetables. However, some fungi benefit their hosts by aiding plant survival. Colletotrichum tofieldiae (Ct) is a root mold which typically supports continued plant development even when the plant is starved of phosphorus, an important nutrient for photosynthesis and growth. Researchers studied a unique pathogenic strain of the fungi, called Ct3, which conversely inhibits plant growth.
Published Researchers to study Alzheimer's disease in marmosets
(via sciencedaily.com) Original source Neuroscientists created the first non-human primate model of hereditary Alzheimer's in marmosets to accelerate the pace of drug discovery and rebuild the foundation for future translational studies.
Published New ribozyme can make RNA molecules accessible for click chemistry in living cells
(via sciencedaily.com) Important progress for RNA research: A team has discovered a new ribozyme that can label RNA molecules in living cells.
Published Bird flu is undergoing changes that could increase the risk of widespread human transmission
(via sciencedaily.com) Original source A new study has shown that a subtype of avian flu virus, endemic in poultry farms in China, is undergoing mutational changes, which could increase the risk of the disease being passed on to humans.
Published Immune cells shape their own path
(via sciencedaily.com) Original source When fighting disease, our immune cells need to reach their target quickly. Researchers have now discovered that immune cells actively generate their own guidance system to navigate through complex environments. This challenges earlier notions about these movements. The researchers' findings enhance our knowledge of the immune system and offer potential new approaches to improve human immune response.
Published Digging deeper into how vaccines work against parasitic disease
(via sciencedaily.com) Original source Researchers have determined how Leishmaniasis vaccine candidates, created using mutated disease-causing parasites, prompt molecular-level changes in host cells that have specific roles in helping generate the immune response.
Published Scientists unpick how lung cells induce immune response to influenza
(via sciencedaily.com) Original source Researchers have discovered some new and surprising ways that viral RNA and influenza virus are detected by human lung cells, which has potential implications for treating people affected by such viruses.
Published Mutation rates in whales are much higher than previously reported
(via sciencedaily.com) Original source An international team of marine scientists has studied the DNA of family groups from four different whale species to estimate their mutation rates. Using the newly determined rates, the group found that the number of humpback whales in the North Atlantic before whaling was 86 percent lower than earlier studies suggested.
Published The search for the super potato
(via sciencedaily.com) Original source As climate change continues to pose severe challenges to ensuring sustainable food supplies around the world, scientists are looking for ways to improve the resilience and nutritional quality of potatoes. Scientists have assembled the genome sequences of nearly 300 varieties of potatoes and its wild relatives to develop more nutritious, disease-free, and weather-proof crop. A team has now created a potato super pangenome to identify genetic traits that can help produce the next super spud.
Published A new breakthrough in obesity research may allow you to lose fat while eating all you want
(via sciencedaily.com) Original source This is a significant development that brings hope to the one billion individuals with obesity worldwide. Researchers have discovered new insights into the regulation of fat metabolism. The focus of their study lies within the star-shaped non-neuronal cells in the brain, known as 'astrocytes'. Furthermore, the group announced successful animal experiments using the newly developed drug 'KDS2010', which allowed the mice to lose weigh without dietary restrictions.