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Categories: Biology: Genetics, Paleontology: Early Mammals and Birds
Published Humans' ancestors survived the asteroid impact that killed the dinosaurs
(via sciencedaily.com) Original source A Cretaceous origin for placental mammals, the group that includes humans, dogs and bats, has been revealed by in-depth analysis of the fossil record, showing they co-existed with dinosaurs for a short time before the dinosaurs went extinct.
Published Researchers develop digital test to directly measure HIV viral load
(via sciencedaily.com) Original source A milliliter of blood contains about 15 individual drops. For a person with human immunodeficiency virus (HIV), each drop of blood could contain anywhere from fewer than 20 copies of the virus to more than 500,000 copies. Called the viral load, this is what is measured to allow clinicians to understand how patients are responding to anti-viral medications and monitor potential progression. The time-consuming viral load testing needs to be repeated several times as a patient undergoes treatment. Now, a research team has developed a time and cost-efficient digital assay that can directly measure the presence of HIV in single drop of blood.
Published Megalodon was no cold-blooded killer
(via sciencedaily.com) Original source How the megalodon, a shark that went extinct 3.6 million years ago, stayed warm was a matter of speculation among scientists. Using an analysis of tooth fossils from the megalodon and other sharks of the same period, a study suggests the animal was able to maintain a body temperature well above the temperature of the water in which it lived. The finding could help explain why the megalodon went extinct during the Pliocene Epoch.
Published How coral reefs can survive climate change
(via sciencedaily.com) Original source Similar to the expeditions of a hundred or two hundred years ago, the Tara Pacific expedition lasted over two years. The goal: to research the conditions for life and survival of corals. The ship crossed the entire Pacific Ocean, assembling the largest genetic inventory conducted in any marine system to date. The team's 70 scientists from eight countries took around 58,000 samples from the hundred coral reefs studied.
Published Extinct warbler's genome sequenced from museum specimens
(via sciencedaily.com) Original source The Bachman's warbler, a songbird that was last seen in North America nearly 40 years ago, was a distinct species and not a hybrid of its two living sister species, according a new study in which the full genomes of seven museum specimens of the bird were sequenced.
Published Drug decelerates bacterial race to antibiotic resistance
(via sciencedaily.com) Original source Researchers report that, in laboratory cultures and animal models, a drug significantly reduces the ability of bacteria to develop antibiotic resistance, which might prolong antibiotic effectiveness.
Published Researcher uses pressure to understand RNA dynamics
(via sciencedaily.com) Original source Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn. Scientists are studying the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.
Published The molecular control center of our protein factories
(via sciencedaily.com) Original source Researchers have deciphered a biochemical mechanism that ensures that newly formed proteins are processed correctly when they leave the cell's own protein factories. This solves a decade-old puzzle in protein sorting.
Published The clue is in the glue -- Nature's secret for holding it together
(via sciencedaily.com) Original source An obscure aquatic plant has helped to explain how plants avoid cracking up under the stresses and strains of growth.
Published A roadmap for gene regulation in plants
(via sciencedaily.com) Original source For the first time, researchers have developed a genome-scale way to map the regulatory role of transcription factors, proteins that play a key role in gene expression and determining a plant's physiological traits. Their work reveals unprecedented insights into gene regulatory networks and identifies a new library of DNA parts that can be used to optimize plants for bioenergy and agriculture.
Published Now, every biologist can use machine learning
(via sciencedaily.com) Original source Scientists have built a new, comprehensive AutoML platform designed for biologists with little to no ML experience. New automated machine learning platform enables easy, all-in-one analysis, design, and interpretation of biological sequences with minimal coding. Their platform, called BioAutoMATED, can use sequences of nucleic acids, peptides, or glycans as input data, and its performance is comparable to other AutoML platforms while requiring minimal user input.
Published DNA can fold into complex shapes to execute new functions
(via sciencedaily.com) Original source DNA can mimic protein functions by folding into elaborate, three-dimensional structures, according to a new study.
Published Plant extracts used by indigenous people hold promise in treatment of ataxia
(via sciencedaily.com) Original source Researchers have discovered that extracts from plants used by the Kwakwaka'wakw First Nations peoples in their traditional botanical medicine practices are able to rescue the function of ion channel proteins carrying mutations that cause human Episodic Ataxia.
Published Researchers reveal mechanism of protection against breast and ovarian cancer
(via sciencedaily.com) Original source Researchers have outlined the structure and function of a protein complex which is required to repair damaged DNA and protect against cancer.
Published Scientists discover new embryonic cell type that self-destructs to protect the developing embryo
(via sciencedaily.com) Original source Scientists have uncovered a new quality control system that removes damaged cells from early developing embryos.
Published Completing genome of rusty patched bumble bee may offer new approach to saving endangered bee
(via sciencedaily.com) Original source A detailed, high-resolution map of the rusty patched bumble bee's genome has been released, offering new approaches for bringing the native pollinator back from the danger of extinction. Putting together the rusty patched bumble bee genome is part of the Beenome 100 project, a first-of-its-kind effort to create a library of high-quality, highly detailed genome maps of 100 or more diverse bee species found in the United States.
Published Cryo conservation: A cool solution to saving species from extinction
(via sciencedaily.com) Original source In the face of the biodiversity crisis, and alarming data showing a 69% decline in global animal populations since 1970, researchers are banking on a cool solution to help save species from extinction. Much like egg-freezing is used to preserve human fertility options for a later date, the cryo-freezing of genetic samples taken from animals may play an essential role in curbing species extinctions. A new study sheds light on the immense potential of living cell banks, also known as cryobanks, to contribute to global conservation priorities.
Published A new tool to study complex genome interactions
(via sciencedaily.com) Original source Genome Architecture Mapping captures complex, multi-way interactions in the genome. This is different than the workhorse technique of 3D genomics, which sees mostly two-way contacts, finds a new study.
Published From cross to self-pollination
(via sciencedaily.com) Original source Biologists provide evidence for an alternative genetic mechanism that can lead to plants becoming self-pollinators.
Published Tethering of shattered chromosomal fragments paves way for new cancer therapies
(via sciencedaily.com) Original source Scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations.