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Categories: Biology: Genetics, Chemistry: General
Published Researchers are closing in on a mouse model for late-onset Alzheimer's



Researchers are working to create the first strain of mice that's genetically susceptible to late-onset Alzheimer's, with potentially transformative implications for dementia research.
Published A single-molecule-based organic porous material with great potential for efficient ammonia storage



Novel porous crystalline solid shows promise as an efficient and durable material for ammonia (NH3) capture and storage, report scientists. Made through a simple reprecipitation process, the proposed organic compound can reversibly adsorb and release NH3 via simple pressurization and decompression at room temperature. Its stability and cost-effectiveness make this material a promising energy carrier for future hydrogen economies.
Published Research sheds light on the role of PTPRK in tissue repair and cancer



New research has advanced our knowledge of multiple roles for PTPRK, a receptor tyrosine phosphatase linked to the regulation of cell-cell adhesion, growth factor signalling and tumor suppression. Through a characterization of the function of PTPRK in human cell lines and mice, the team distinguished catalytic and non-catalytic functions of PTPRK. The findings extend what is known about the signalling mechanisms involving PTPRK as a phosphatase and its role in colorectal health but also shed new light on the extent of its function via non-catalytic signalling mechanisms.
Published Under pressure: How cells respond to physical stress



Cell membranes play a crucial role in maintaining the integrity and functionality of cells. However, the mechanisms by which they perform these roles are not yet fully understood. Scientists have used cryo-electron microscopy to observe how lipids and proteins at the plasma membrane interact and react to mechanical stress. This work shows that, depending on conditions, small membrane regions can stabilize various lipids to trigger specific cellular responses. These discoveries confirm the existence of well-organized lipid domains and begin to reveal the role they play in cell survival.
Published Drawing water from dry air



A prototype device harvests drinking water from the atmosphere, even in arid places.
Published Researchers develop more environmentally friendly and cost-effective method for soil remediation



Chemists have developed a rapid electrothermal mineralization (REM) process, which in seconds can remediate the accumulation of synthetic chemicals that can contaminate soil and the environment.
Published Nanoscopic imaging aids in understanding protein, tissue preservation in ancient bones



A pilot study shows that nanoscopic 3-D imaging of ancient bone not only provides further insight into the changes soft tissues undergo during fossilization, it also has potential as a fast, practical way to determine which specimens are likely candidates for ancient DNA and protein sequence preservation.
Published 3D-printed microstructure forest facilitates solar steam generator desalination



Faced with the world's impending freshwater scarcity, researchers turned to solar steam generators, which are emerging as a promising device for seawater desalination. The team sought design inspiration from trees and harnessed the potential of 3D printing. They present technology for producing efficient SSGs for desalination and introduces a novel method for printing functional nanocomposites for multi-jet fusion. Their SSGs were inspired by plant transpiration and are composed of miniature tree-shaped microstructures, forming an efficient, heat-distributing forest.
Published Dual action antibiotic could make bacterial resistance nearly impossible



New drug that disrupts two cellular targets would make it much harder for bacteria to evolve resistance.
Published Pioneering the cellular frontier



Scientists use a multimodal approach that combines hard X-ray computed tomography and X-ray fluorescence imaging to see the structure and chemical processes inside of a single cell.
Published New rapid method for determining virus infectivity



A new method that can rapidly determine whether a virus is infectious or non-infectious could revolutionize the response to future pandemics, researchers report.
Published Fruit fly post-mating behavior controlled by male-derived peptide via command neurons, study finds



Scientists have succeeded in pinpointing the neurons within a female fruit fly's brain that respond to signals from the male during mating.
Published A promising new method uses light to clean up forever chemicals



A room-temperature method to decompose perfluoroalkyl substances (PFASs) using visible LED light offers a promising solution for sustainable fluorine recycling and PFAS treatment.
Published Converting captured carbon to fuel: Study assesses what's practical and what's not



A new analysis sheds light on major shortfalls of a recently proposed approach to capture CO2 from air and directly convert it to fuel using electricity. The authors also provide a new, more sustainable, alternative.
Published New genetic test will eliminate a form of inherited blindness in dogs



Scientists have identified the genetic mutation that causes progressive retinal atrophy in English Shepherd Dogs, which results in incurable blindness, and developed a genetic test to help eliminate the disease from future generations of the breed.
Published Exposing dengue's invasion strategies



Mosquito-borne viral infections once confined to tropical regions are spreading. Dengue virus infects up to 400 million people worldwide each year according to World Health Organization estimates, and no available treatments exist for this disease. Now, research uncovered surprising strategies for how dengue and hundreds of other viruses replicate in their hosts, with the potential to aid in developing novel antiviral treatments and vaccines.
Published Controlling mosquito populations through genetic breeding



Researchers have found a new way to identify genetic targets useful for control of mosquito populations, potentially offering an alternative to insecticides. Their study focused on the genetic basis of species incompatibility. They crossed Ae. aegypti, a major global arboviral disease vector, and its sibling species, Ae. mascarensis, from the Indian Ocean. When offspring is crossed back with one parent, about 10 percent of the progeny becomes intersex and is unable to reproduce.
Published Not everything that tastes bitter is potentially harmful: But why? Study provides an explanation



A bitter taste is traditionally considered a warning sign of potentially toxic substances. But not all bitter substances are harmful. For example, some peptides and free amino acids taste bitter, even though they are non-toxic, nutritious and sometimes even vital for humans. A new study now offers an explanation for this seemingly paradoxical phenomenon.
Published Transient structure in fly leg holds clue to insect shape formation



A little leg may reveal something big about how closely related insect species can drastically differ in body shape, according to a new study. The team imaged live cells of fruit flies in the last stages of development over several days and found a new structure that appears to help guide a section of the leg into its final shape.
Published Switching from gas to electric stoves cuts indoor air pollution



Switching from a gas stove to an electric induction stove can reduce indoor nitrogen dioxide air pollution, a known health hazard, by more than 50 percent according to new research.