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Categories: Biology: Genetics, Paleontology: Fossils

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Investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.

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What if, by adding a couple of cell layers inside a corn kernel, the grain could become significantly richer in essential nutrients like iron, zinc, and protein? Such an improvement could benefit people who rely on corn for a large portion of their diet, as in many parts of the global south.

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Certain stem cells have a unique ability to move between growth compartments in hair follicles, but get stuck as people age and so lose their ability to mature and maintain hair color, a new study shows.

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Two protein complexes carry the major responsibility for the spatial organization of chromosomes in our cell nuclei. DNA tension plays a surprising role in this. Nanoscientists now publish how they have visualized this.

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A hitherto unknown mechanism for DNA folding is described in a new study. The findings provide new insights into chromosomal processes that are vital to both normal development and to prevent disease.

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We now know more about the diet of a prehistoric creature that grew up to two and a half meters long and lived in Australian waters during the time of the dinosaurs, thanks to the power of x-rays. Researchers used micro-CT scans to peer inside the fossilized stomach remains of a small marine reptile -- a plesiosaur nicknamed 'Eric' after a song from the comedy group Monty Python -- to determine what the creature ate in the lead up to its death.

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Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation between the Universities of Amsterdam and Leiden, researchers have developed dedicated molecular nanocages for siRNA delivery. In a paper just out in the Journal Chem they present nanocages that are easy to prepare and display tuneable siRNA delivery characteristics.

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Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail. This technology has potential uses in tissue engineering, regenerative medicine, and understanding how the body works. The scientists applied their new method to control the glow of a green fluorescent protein derived from Japanese eel muscle.

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Researchers have discovered how long ago the Australian Nullarbor plain dried out, with a new approach shedding light on how ancient climate change altered some of the driest regions of our planet.

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New fossils in amber have revealed that beetles fed on the feathers of dinosaurs about 105 million years ago, showing a symbiotic relationship of one-sided or mutual benefit.

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For more than half a century, the Tully monster (Tullimonstrum gregarium), an enigmatic animal that lived about 300 million years ago, has confounded paleontologists, with its strange anatomy making it difficult to classify. Recently, a group of researchers proposed a hypothesis that Tullimonstrum was a vertebrate similar to cyclostomes (jawless fish like lamprey and hagfish). If it was, then the Tully monster would potentially fill a gap in the evolutionary history of early vertebrates. Studies so far have both supported and rejected this hypothesis. Now, using 3D imaging technology, a team in Japan believes it has found the answer after uncovering detailed characteristics of the Tully monster which strongly suggest that it was not a vertebrate. However, its exact classification and what type of invertebrate it was is still to be decided.

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Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created infertility only in the males, impacting their sperm count, movement and shape.

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A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings. A study now shows how two molecular mechanisms can work together make the bacterium extra resistant.

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Insect pollination is a decisive process for the survival and evolution of angiosperm (flowering) plants and, to a lesser extent, gymnosperms (without visible flower or fruit). There is a growing interest in studies on the origins of the relationship between insects and plants, especially in the current context of the progressive decline of pollinating insects on a global scale and its impact on food production. Pollinating insects can be recognized in the fossil record, although to date, there has been no protocol for their differentiation. Fossil pollinators have been found in both rock and amber deposits, and it is in rock deposits that the first evidence of plant pollination by insects is being studied across the globe. But how can we determine which was a true insect pollinator in the past?

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Studying mass extinction events from the past can build our understanding of how ecosystems and the communities of organisms within them respond. Researchers are looking to the Late Devonian mass extinction which happened around 370 million years ago to better understand how communities of organisms respond in times of great upheaval.

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Scientists have developed a software package to help answer key questions about genetic factors associated with shared characteristics among different species.

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Researchers describe how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body's ability to suppress it.

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Origin-of-life chemists propose that glyoxylate could have been the original source of sugars on the 'prebiotic' Earth

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Scientists are reporting a discovery about unexpected asymmetry on the hair cells of zebrafish that allow them to detect movement with greater sensitivity from the back than the front.

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New research led by a paleobotanist provides clues about what plants existed in the Burnaby Mountain area (British Columbia, Canada) 40 million years ago during the late Eocene, when the climate was much warmer than it is today.