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Categories: Biology: Genetics, Paleontology: Fossils

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By studying mutations in yeast and human cells, scientists say they have found that biochemical bonds between fats and proteins in the mitochondrion, the cell's powerhouse, play a crucial role in how our cells produce energy.

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Biomedical engineers have developed a silk-based, ultrathin membrane that can be used in organ-on-a-chip models to better mimic the natural environment of cells and tissues within the body. When used in a kidney organ-on-a-chip platform, the membrane helped tissues grow to recreate the functionality of both healthy and diseased kidneys.

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What species live in this coral reef, and are they healthy? Chemical clues emitted by marine organisms might hold that information. But in underwater environments, invisible compounds create a complex 'soup' that is hard for scientists to decipher. Now, researchers have demonstrated a way to extract and identify these indicator compounds in seawater. They found metabolites previously undetected on reefs, including three that may represent different reef organisms.

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Advanced technologies enable the controlled release of medicine to specific cells in the body. Scientists argue these same technologies must be applied to agriculture if growers are to meet increasing global food demands.

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Researchers have been investigating the molecular mechanisms responsible for determining sex in ants. Although the vast majority of an ant colony consists of female workers, males are essential to the continuing survival of the species. In order to uncover the mechanisms involved, the researchers decided to focus on diploid males, which occasionally occur in the Argentine ant.

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Researchers provide the first insight into the mode of action of the lipopeptide serrawettin W2-FL10, derived from Serratia marcescens. This lipopeptide targets the cell membrane of S. aureus, causing lesions which result in the leakage of intracellular components and ultimately cell death.

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Around 100 million years ago, a remarkable evolutionary shift allowed placental mammals to diversify and conquer many cold regions of our planet. New research shows that the typical mammalian heater organ, brown fat, evolved exclusively in modern placental mammals. The research team demonstrated that marsupials, our distant relatives, possess a not fully evolved form of brown fat. They discovered that the pivotal heat-producing protein called UCP1 became active after the divergence of placental and marsupial mammals. This finding is crucial for understanding the role of brown fat in mammalian evolution, endothermy, and metabolism.

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In a parasitic first, a Baltic amber specimen has revealed that millions of years ago tiny worms known as nematodes were living inside of and feeding on the outer protective layer of pseudoscorpions.

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The identity of a prehistoric marine reptile has finally been revealed after experts discovered that some of its remains actually belonged to fish.

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Geobiologists reported a 550 million-year-old sea sponge that had been missing from the fossil record. The discovery sheds new light on a conundrum that has stumped zoologists and paleontologists for years.

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Researchers invented a technique that allows them to observe which genes and enhancers are active in a cell at the same time. This could help them determine which enhancers control which genes and may reveal potential new drug targets for genetic disorders.

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A recent study provides new insights into how fathers' diets and overweight can affect their children's health even before conception. The findings of the study can help develop preventive health measures for men wishing to become fathers: The healthier the father's diet, the lower the risk for their children to develop obesity or diseases such as diabetes later in life.

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Maternal obesity impacts the eating behaviors of offspring via long-term overexpression of the microRNA miR-505-5p, according to a new study.

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A team of palaeontologists has discovered a fossil of a gigantic flying reptile from the Jurassic period with an estimated wingspan of more than three metres -- making it one of the largest pterosaurs ever found from that era.

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Scientists have discovered some of the molecular mechanisms controlling how plants -- including important crops like soybean and rice -- will respond to rising global temperatures, finding higher temperatures make root systems grow faster, but sustaining this increased growth speed depends on high levels of nitrogen and phosphorus in the soil. The discoveries point to the necessity of nitrogen and phosphorus-rich soil to promote crop growth and create nutritious crops, in addition to aiding a mission to create more resilient crops in the face of climate change.

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Under certain conditions, some algae are able to produce hydrogen -- a much sought-after green energy source. Its production takes place in the unique catalytic center of the unicellular algae and is only possible if certain cofactors of the relevant proteins are present. Researchers have identified how such a cofactor, the so-called hydrogen cluster, is assembled. Specifically, they describe the previously unexplained role of the enzyme HydF, which is involved in the final steps of assembly.

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An international team has found a new RNA virus that they believe is hitching a ride with a common human parasite. The virus is associated with severe inflammation in humans infected with the parasite Toxoplasma gondii, leading the team to hypothesize that it exacerbates toxoplasmosis disease.

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Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct. The research could help improve ways to protect food security and human lives.

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This fossil looks like a lumpy, rounded rock with a couple of exposed teeth that are a little worse for wear, having been submerged and tumbled along the floor of the Gulf of Mexico for thousands of years before washing up on a beach. But when it was X-rayed a doctoral student saw there was more to the fossil that met the eye: a hidden canine tooth that had not yet erupted from the jaw bone. It was just what researchers needed to identify the fossil as belonging to a Homotherium, a genus of large cat that roamed much of the Earth for millions of years.

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Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.