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Categories: Biology: Genetics, Paleontology: Fossils
Published Fruit fly wing research offers window into birth defects
(via sciencedaily.com) Original source If fruit fly wings do not develop into the right shape, the flies will die. Researchers have learned how fly embryo cells develop as they need to, opening a window into human development and possible treatments for birth defects.
Published Ancient arachnid from coal forests of America stands out for its spiny legs
(via sciencedaily.com) Original source The spiny legged 308-million-year-old arachnid Douglassarachne acanthopoda was discovered the famous Mazon Creek locality.
Published A new 'rule of biology' may have come to light, expanding insight into evolution and aging
(via sciencedaily.com) Original source A molecular biologist may have found a new 'rule of biology.' The rule challenges long-held notions that most living organisms prefer stability over instability because stability requires less energy and fewer resources.
Published New sensor gives unprecedented look at changes in cell's energy 'currency'
(via sciencedaily.com) Original source A new sensor is giving researchers the best look yet at ATP levels inside living cells, enabling scientists to study in greater detail than ever before how fluctuations in this cellular currency affect the cell and contribute to disease.
Published How did sabre-toothed tigers acquire their long upper canine teeth?
(via sciencedaily.com) Original source In a groundbreaking study an international team of scientists has investigated the evolutionary patterns behind the development of sabre teeth, with some unexpected results along the way.
Published Bioengineered enzyme creates natural vanillin from plants in one step
(via sciencedaily.com) Original source Vanilla, the most widely used flavoring compound in confectionaries and cosmetics, gets its sweet flavor and aroma from the chemical compound -- 'vanillin'. However, the large-scale production of natural vanillin is impeded by the lack of microbial processes and enzymes which can commercially generate vanillin. Now, researchers have genetically engineered a novel enzyme which can convert ferulic acid from plant waste into vanillin in a one-step sustainable process.
Published Heating proteins to body temperature reveals new drug targets
(via sciencedaily.com) Original source Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications. The findings could revolutionize wide swathes of biology by fundamentally changing how protein structure is studied and leveraged for drug design.
Published Now we know, what gets roots to grow: Can help in future droughts
(via sciencedaily.com) Original source A biological mechanism familiar to people who fast helps plant roots grow strong. The discovery provides an answer to a long-unanswered question and a deeper understanding of the 'mouths' of plants that can help to develop climate-resilient crops.
Published Exploring the mechanism behind drug eruptions in the skin
(via sciencedaily.com) Original source Although drug eruptions are often linked to the human leukocyte antigen (HLA), the mechanism of its involvement in presenting symptoms of the skin remains unclear. In a recent study, researchers used genetically engineered mice to demonstrate the role of HLA in mediating intracellular reactions in keratinocytes, leading to drug eruptions in the skin. Their findings could lead to improved preventive and treatment measures for drug eruptions.
Published Drug compounds to combat neurodegenerative diseases
(via sciencedaily.com) Original source Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins. Prion disease is an umbrella term for a group of fatal and currently untreatable neurodegenerative diseases that not only affect humans, but also wild and captive animals. These diseases include Creutzfeldt-Jakob disease (CJD) in humans, bovine spongiform encephalopathy (BSE, or 'mad cow disease'), and chronic wasting disease (CWD) affecting deer, elk and moose.
Published Some mice may owe their monogamy to a newly evolved type of cell
(via sciencedaily.com) Original source What makes the oldfield mouse steadfastly monogamous throughout its life while its closest rodent relatives are promiscuous? The answer may be a previously unknown hormone-generating cell. Scientists discover the cells and hormones that inspire mice to nurture their young; the same hormones are also present in humans.
Published Genetics provide key to fight crown-of-thorns starfish
(via sciencedaily.com) Original source Scientists are one step closer to combating coral-destroying crown-of-thorns starfish, following a study into the pest's genetics.
Published Persistent strain of cholera defends itself against forces of change, scientists find
(via sciencedaily.com) Original source A longstanding mystery about the strain of Vibrio cholerae (V. cholerae) responsible for the seventh global cholera pandemic is how this lineage has managed to out-compete other pathogenic variants. The team identified a unique quirk of the immune system that protects the bacteria from a key driver of bacterial evolution.
Published Insights into protein evolution
(via sciencedaily.com) Original source A research team has unveiled a breakthrough in understanding how specific genetic sequences, known as pseudogenes, evolve.
Published Fruit fly testes offer potential tool against harmful insects
(via sciencedaily.com) Original source A way to curb nagging insects has been flying under our radar -- an enzyme from fruit fly testes. The compound could control bugs that carry disease and harm crops by stunting their ability to procreate, researchers have found.
Published New viruses that could cause epidemics on the horizon
(via sciencedaily.com) Original source Suddenly they appear and -- like the SARS-CoV-2 coronavirus -- can trigger major epidemics: Viruses that nobody had on their radar. They are not really new, but they have changed genetically. In particular, the exchange of genetic material between different virus species can lead to the sudden emergence of threatening pathogens with significantly altered characteristics.
Published Like dad and like mum ... all in one plant
(via sciencedaily.com) Original source Scientists have established a system to generate clonal sex cells in tomato plants and used them to design the genomes of offspring. The fertilization of a clonal egg from one parent by a clonal sperm from another parent led to plants containing the complete genetic information of both parents.
Published Research on centromere structure yields new insights into the mechanisms of chromosome segregation errors
(via sciencedaily.com) Original source Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in chromosome segregation can lead to cell death and cancer development. The researchers discovered that the centromere consists of two subdomains. This fundamental finding has important implications for the process of chromosome segregation and provides new mechanisms underlying erroneous divisions in cancer cells. The research was published in Cell on May 13th 2024.
Published How do genetically identical water fleas develop into male or female?
(via sciencedaily.com) Original source Researchers have used a novel combination of short-read and long-read RNA sequencing to identify the different isoforms of genes expressed in the crustacean Daphnia magna. Males and females are genetically identical, but using this technique the team revealed genes that switch the predominant isoform in a male-female-dependent manner. This study may help further advance technologies in crustacean aquaculture.
Published Research shows that 'softer' proteins can cross into the nucleus quicker
(via sciencedaily.com) Original source Researchers have discovered that how soft or rigid proteins are in certain regions can dictate how fast or slow they enter the nucleus.