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Categories: Biology: Genetics, Paleontology: Fossils
Published Researchers discover how we perceive bitter taste
(via sciencedaily.com) Original source A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the researchers were also able to determine where bitter-tasting substances bind to TAS2R14 and how they activate them. The findings may lead to the development of drugs that targeting taste receptors.
Published Cockayne syndrome: New insights into cellular DNA repair mechanism
(via sciencedaily.com) Original source Researchers decode repair mechanism during transcription of genetic information.
Published Machine learning method reveals chromosome locations in individual cell nucleus
(via sciencedaily.com) Original source Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene expression and disease processes.
Published Do some mysterious bones belong to gigantic ichthyosaurs?
(via sciencedaily.com) Original source Several similar large, fossilized bone fragments have been discovered in various regions across Western and Central Europe since the 19th century. The animal group to which they belonged is still the subject of much debate to this day. A study could now settle this dispute once and for all: The microstructure of the fossils indicates that they come from the lower jaw of a gigantic ichthyosaur. These animals could reach 25 to 30 meters in length, a similar size to the modern blue whale.
Published New diagnostic tool achieves accuracy of PCR tests with faster and simpler nanopore system
(via sciencedaily.com) Original source A new diagnostic tool developed by researchers can test for SARS-CoV-2 and Zika virus with the same or better accuracy as high-precision PCR tests in a matter of hours.
Published Different means to the same end: How a worm protects its chromosomes
(via sciencedaily.com) Original source Researchers have discovered that a worm commonly used in the study of biology uses a set of proteins unlike those seen in other studied organisms to protect the ends of its DNA.
Published Toothed whale echolocation organs evolved from jaw muscles
(via sciencedaily.com) Original source Genetic analysis finds evidence suggesting that acoustic fat bodies in the heads of toothed whales were once the muscles and bone marrow of the jaw.
Published Bringing multidrug-resistant pathogens to their knees
(via sciencedaily.com) Original source Multidrug-resistant bacterial infections that cannot be treated by any known antibiotics pose a serious global threat. A research team has now introduced a method for the development of novel antibiotics to fight resistant pathogens. The drugs are based on protein building blocks with fluorous lipid chains.
Published Integrated dataset enables genes-to-ecosystems research
(via sciencedaily.com) Original source A new dataset bridging molecular information about the poplar tree microbiome to ecosystem-level processes has been released. The project aims to inform research regarding how natural systems function, their vulnerability to a changing climate, and ultimately how plants might be engineered for better performance as sources of bioenergy and natural carbon storage.
Published Dinosaur study challenges Bergmann's rule
(via sciencedaily.com) Original source A new study calls into question Bergmann's rule, an 1800s-era scientific principle stating that animals in high-latitude, cooler climates tend to be larger than close relatives living in warmer climates.
Published Can language models read the genome? This one decoded mRNA to make better vaccines
(via sciencedaily.com) Original source Researchers developed a foundational language model to decode mRNA sequences and optimize those sequences for vaccine development. The tool shows broader promise as a means for studying molecular biology.
Published Rusty-patched bumblebee's struggle for survival found in its genes
(via sciencedaily.com) Original source The rusty-patched bumblebee, once common in the United States, has declined from about 90% of its former range. Researchers conducted the first range-wide genetic study of the endangered species to inform recovery efforts.
Published Heat flows the secret to order in prebiotic molecular kitchen
(via sciencedaily.com) Original source Biophysicists have demonstrated how heat flows through rock fissures could have created the conditions for the emergence of life.
Published New tools reveal how genes work and cells organize
(via sciencedaily.com) Original source Researchers have discovered how certain proteins can attach to special structures in RNA, called G-quadruplexes. Additionally, they have developed computational tools capable of predicting these protein-RNA interactions. The newfound ability to predict these interactions can help future work in understanding molecular pathways in the cell and pave the way for developing drugs targeting these RNA G-quadruplex binding proteins, that are found to be involved in disease such as cancer.
Published New sunflower family tree reveals multiple origins of flower symmetry
(via sciencedaily.com) Original source A new sunflower family tree used skimmed genomes to increase the number of species sampled, revealing that flower symmetry evolved multiple times independently, a process called convergent evolution, among the members of this large plant family.
Published Evolution in action? New study finds possibility of nitrogen-fixing organelles
(via sciencedaily.com) Original source A new study finds that UCYN-A, a species of nitrogen-fixing cyanobacteria, may be evolving organelle-like characteristics.
Published Early dinosaurs grew up fast, but they weren't the only ones
(via sciencedaily.com) Original source The earliest dinosaurs had rapid growth rates, but so did many of the other animals living alongside them, according to a new study.
Published New discovery unravels malaria invasion mechanism
(via sciencedaily.com) Original source A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study reveals the role of a sugar called sialic acid in this invasion process. The findings have major implications for malaria vaccine and drug development.
Published First view of centromere variation and evolution
(via sciencedaily.com) Original source A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. Although centromeres are vital to proper cell replication by assuring faithful transmision of genetic materials when cells divide, the complexity of their genomic organization had been almost impossible to study. The lack of centromere sequences hindered exploration of how these regions help maintain genetic integrity. Now, advanced technologies have shown scientists how greatly centromeres differ in size and structure.
Published When did the chicken cross the road? New evidence from Central Asia
(via sciencedaily.com) Original source An international team of scholars present the earliest clear archaeological and biomolecular evidence for the raising of chickens for egg production, based on material from 12 archaeological sites spanning one and a half millennia. The research indicates that the domestic chicken, now a staple in diets around the world, is not as ancient as previously thought.