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Categories: Biology: Genetics, Paleontology: Fossils
Published Crocodile family tree mapped: New light shed on croc evolution



Around 250 million years ago, 700 species of reptiles closely related to the modern-day crocodile roamed the earth, now new research reveals how a complex interplay between climate change, species competition and habitat can help explain why just 23 species of crocodile survive today.
Published New technique efficiently offers insight into gene regulation



Researchers have developed a new technique called MAbID. This allows them to simultaneously study different mechanisms of gene regulation, which plays a major role in development and disease. MAbID offers new insights into how these mechanisms work together or against each other.
Published Genomic study sheds light on how carnivorous Asian pitcher plants acquired signature insect trap



Scientists sequenced the genome of the East Asian pitcher plant, Nepenthes gracilis, a species of carnivorous plant related to Venus flytraps, as well as sundews, beets and spinach.
Published A mixed origin made maize successful



Maize is one of the world's most widely grown crops. It is used for both human and animal foods and holds great cultural significance, especially for indigenous peoples in the Americas. Yet despite its importance, the origins of the grain have been hotly debated for more than a century. Now new research shows that all modern maize descends from a hybrid created just over 5000 years ago in central Mexico, thousands of years after the plant was first domesticated.
Published Dishing the dirt on human evolution: Why scientific techniques matter in archaeology



Scientists should seek answers hidden in the dirt using proven and state-of-the-art archaeological science techniques to support new discoveries about human evolution following recent controversies at a cave site in Africa, says a group of international experts. Their recommendations follow claims published in June of this year that Homo naledi --a small-brained human species -- buried their dead in Rising Star Cave, South Africa, between 335,000 and 241,000 years ago, and may also have decorated the cave walls with engravings.
Published Unknown animals were leaving bird-like footprints in Late Triassic Southern Africa



Ancient animals were walking around on bird-like feet over 210 million years ago, according to a new study.
Published Clever dosage control mechanism of biallelic genes



Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study identified the epigenetic regulator MSL2 an 'anti-monoallelic' factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.
Published Key protein in blood vessel's growth identified



New research identifies the class II PI3K-C2b protein, a member of the PI3 family of kinases, as one of the key regulators of blood vessels growth in humans and other mammals. Mutations in these family of proteins may lead to vascular malformations and the precise understanding of the whole process is instrumental in opening the door to new therapeutic approaches in the future.
Published Researchers decipher enzyme scissors of intestinal microbes



Fruit and vegetables contain a variety of plant natural products such as flavonoids, which give fruits their colour and are said to have health-promoting properties. Most plant natural products occur in nature as glycosides, i.e. chemical compounds with sugars. In order for humans to absorb the healthy plant natural products, the sugar must be split off in the intestine. Microorganisms in the intestinal flora help to speed up the process. So-called C-glycosides, i.e. plant natural products with a carbon-based bond to a sugar, would even be practically indigestible without the intestinal microbes (e.g. nothofagin in rooibos tea).
Published Releasing brakes on biocatalysis



Enzymes from microorganisms can produce hydrogen (H2) under certain conditions, which makes them potential biocatalysts for biobased H2 technologies. In order to make this hydrogen production efficient, researchers are trying to identify and eliminate possible limiting factors. These include formaldehyde, which occurs naturally as a metabolic product in cells and inhibits the particularly efficient [FeFe] hydrogenase.
Published The venom preceded the stinger: Genomic studies shed light on the origins of bee venom



Bees, wasps and ants belong to the Hymenoptera order and inject a whole cocktail of venomous ingredients when they sting. Despite their tremendous ecological and economic importance, little was previously known about the origins of their venom. Through extensive genomic studies, a team of researchers has now discovered that typical venomous components were already present in the earliest ancestors of Hymenoptera and must therefore have evolved before the stingers of bees and other insects. What's more, and contrary to previous assumptions, the gene for the venom melittin is found solely in bees.
Published Landscape dynamics determine the evolution of biodiversity on Earth



A landmark study into the geological timescale distribution of sediment and nutrients over 500 million years shows that species biodiversity on Earth is driven by landscape dynamics.
Published Tracing the evolution of the 'little brain'



The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans. A research team has now generated comprehensive genetic maps of the development of cells in the cerebella of human, mouse and opossum. Comparisons of these maps reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development.
Published Scientists harness flower 'super power' to pave the way for new drug treatments



Researchers have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells.
Published Study provides fresh insights into antibiotic resistance, fitness landscapes



A new study suggests that E. coli bacteria may have a higher capability to evolve antibiotic resistance than previously believed. Researchers mapped possible mutations in an essential E. coli protein involved in antibiotic resistance and found that 75% of evolutionary paths led to high antibiotic resistance, challenging existing theories about fitness landscapes in evolutionary biology. This discovery may have broader implications for understanding adaptation and evolution in various fields.
Published Earliest known European common hippopotamus fossil reveals their Middle Pleistocene dispersal



Modern hippos first dispersed in Europe during the Middle Pleistocene, according to a new study.
Published Nutrient found in beef and dairy improves immune response to cancer



Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study.
Published Team discovers rules for breaking into Pseudomonas



Researchers report that they have found a way to get antibacterial drugs through the nearly impenetrable outer membrane of Pseudomonas aeruginosa, a bacterium that -- once it infects a person -- is notoriously difficult to treat.
Published A stronger core for better plant breeding



A new software tool with enhanced genome-sequencing powers has been developed, increasing the speed and accuracy at which researchers can improve plants through breeding.
Published Curators and cavers: How a tip from a citizen scientist led to deep discoveries in Utah's caves



Scientists and colleagues from Utah's caving community have published the first research from their collaborative fieldwork effort deep in Utah's caves. The journal's feature article reveals why caves make such compelling research archives; what was uncovered in Boomerang Cave in northern Utah; why skeletal remains provide new access to hard-to-get data from the recent past; and offers a new zoological baseline for mammalian changes in an alpine community.