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Categories: Biology: Genetics, Paleontology: Fossils
Published Scientists one step closer to re-writing world's first synthetic yeast genome, unravelling the fundamental building blocks of life
(via sciencedaily.com) Original source Scientists have engineered a chromosome entirely from scratch that will contribute to the production of the world's first synthetic yeast.
Published Scientists take major step towards completing the world's first synthetic yeast
(via sciencedaily.com) Original source A team of Scientists has completed construction of a synthetic chromosome as part of a major international project to build the world's first synthetic yeast genome. The work represents completion of one of the 16 chromosomes of the yeast genome, which is part of the biggest project ever in synthetic biology; the international synthetic yeast genome collaboration. The collaboration, known as 'Sc2.0' has been a 15-year project involving teams from around the world (UK, US, China, Singapore, UK, France and Australia), working together to make synthetic versions of all of yeast's chromosomes. Alongside this paper, another 9 publications are also released today from other teams describing their synthetic chromosomes. The final completion of the genome project -- the largest synthetic genome ever -- is expected next year.
Published Window to the past: New microfossils suggest earlier rise in complex life
(via sciencedaily.com) Original source Microfossils may capture a jump in the complexity of life that coincided with the rise of oxygen in Earth's atmosphere and oceans, according to an international team of scientists.
Published Cracking the code: Genome sequencing reveals why songbirds are larger in colder climates
(via sciencedaily.com) Original source Scientists have unlocked the genetic basis underlying the remarkable variation in body size observed in song sparrows, one of North America's most familiar and beloved songbirds. This discovery also provides insights into this species' capacity to adapt to the challenges of climate change. The study used genomic sequencing to successfully pinpoint eight genetic variants, or DNA mutations, largely responsible for the nearly threefold difference in body size observed across the song sparrow range from Mexico to Alaska.
Published 450-million-year-old organism finds new life in Softbotics
(via sciencedaily.com) Original source Researchers have used fossil evidence to engineer a soft robotic replica of pleurocystitids, a marine organism that existed nearly 450 million years ago and is believed to be one of the first echinoderms capable of movement using a muscular stem.
Published Plants' ingenious defense against mutational damage
(via sciencedaily.com) Original source How do plants deal with mutations in their 'power stations'? By exploiting randomness to create diversity, say researchers.
Published Fossils tell tale of last primate to inhabit North America before humans
(via sciencedaily.com) Original source Paleontologists have shed light on the long-standing saga of Ekgmowechashala, based on fossil teeth and jaws found in both Nebraska and China. Ekgmowechashala is the last primate found in the fossil record before humans.
Published Frogs were Florida's first-known vertebrates from the Caribbean
(via sciencedaily.com) Original source A new fossil study shows that frogs from the genus Eleutherodactylus are geologically the oldest Caribbean vertebrates to be found in Florida. They made the journey 20 million years ago, when much of Florida was still underwater.
Published New secrets about cat evolution revealed
(via sciencedaily.com) Original source By comparing genomes of several cat species, the project has helped researchers understand why cat genomes tend to have fewer complex genetic variations (such as rearrangements of DNA segments) than other mammal groups, like primates. It also revealed new insights into which parts of cat DNA are most likely to evolve rapidly and how they play a role in species differentiation.
Published New antibiotic approach proves promising against lyme bacterium
(via sciencedaily.com) Original source Using a technique that has shown promise in targeting cancer tumors, a team has found a way to deploy a molecular warhead that can annihilate the bacterium that causes Lyme disease.
Published Research outlines how sex differences have evolved
(via sciencedaily.com) Original source Researchers have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.
Published Female sex determining gene identified in mice
(via sciencedaily.com) Original source Researchers have identified a gene which is an early determining factor of ovary development in mice.
Published A known environmental hazard can change the epigenetics of cells
(via sciencedaily.com) Original source An international team of researchers has discovered that formaldehyde, a widely spread pollutant and common metabolite in our body, interferes in the epigenetic programming of the cell. This finding expands the knowledge of formaldehyde, previously considered only as a DNA mutagen, and helps establishing a further link with cancer.
Published Research connecting gut bacteria and oxytocin provides a new mechanism for microbiome-promoted health benefits
(via sciencedaily.com) Original source Researchers found that the hormone oxytocin, known to be involved in regulating feeding and social behavior and until now to be produced mostly in the brain, is also produced in the human intestine. Furthermore, gut resident bacteria L. reuteri can affect the production of gut-made oxytocin, providing the first insights into a mechanism by which these bacteria can influence human health.
Published Immunology: Dysfunction of mitochondria drives the exhaustion of T cells
(via sciencedaily.com) Original source In the immune system's fight against cancer and infections, the T cells often lose their power. Now immunologists may have found a possible explanation for this phenomenon.
Published New study sheds light on the molecular mechanisms underlying lipid recycling within cells
(via sciencedaily.com) Original source Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers explored the molecular mechanisms leading to the degradation of the phospholipid bilayers making up the cell membranes. Their findings improve our understanding of cellular degradation processes and related metabolic disorders.
Published First mice engineered to survive COVID-19 like young, healthy humans
(via sciencedaily.com) Original source Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a new study.
Published Where is a sea star's head? Maybe just about everywhere
(via sciencedaily.com) Original source A new study that combines genetic and molecular techniques helps solve the riddle of sea star (commonly called starfish) body plans, and how sea stars start life with bilateral body symmetry -- just like humans -- but grow up to be adults with fivefold 'pentaradial' symmetry.
Published How the fish got its shoulder
(via sciencedaily.com) Original source A new analysis of the bones and muscles in ancient fish gives new clues about how the shoulder evolved in animals -- including us.
Published New Nijmegen method reveals hidden genetic variations
(via sciencedaily.com) Original source Many hidden genetic variations can be detected with Chameleolyser, a new method. The information is already yielding new patient diagnoses and may also lead to the discovery of as yet unknown disease genes.