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Categories: Biology: Genetics, Chemistry: Biochemistry

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The discovery of a hybrid population of poplar trees in western Wyoming has provided insight into how natural hybridization informs the evolution of many plant species, according to researchers. They also said their discovery suggests that genetic exchange between species may be critical for adaptation to environmental change.

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High-protein diets, known as 'Paleolithic diets', are popular. Using mouse models, scientists have studied their impact. While effective in regulating weight and stabilizing diabetes, these diets are not without risks. Excess protein greatly increases ammonium production, overwhelming the liver. Excess ammonium can cause neurological disorders and, in severe cases, lead to coma. These results suggest caution when following these diets.

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Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose. Researchers have now identified a strategy to design safer opioids. They showed that an experimental opioid, which binds to an unconventional spot in the receptor, suppresses pain in animal models with fewer side effects -- most notably those linked to fatal overdoses.

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A newly engineered type of soil can capture water out of thin air to keep plants hydrated and manage controlled release of fertilizer for a constant supply of nutrients.

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Genomes can now be used to store information about a variety of transient biological events inside of living cells, as they happen, like a flight recorder collecting data from an aircraft. The method, called ENGRAM, aims to turn cells into their own historians. ENGRAM couples each kind of biological signal or event inside a cell to a symbolic barcode. This new strategy traces and archives the type and timing of biological signals inside the cell by inserting this information into the genome. For example, this record-keeping can track the commands that turn genes on or off.

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Most influenza viruses enter human or animal cells through specific pathways on the cells' surface. Researchers have now discovered that certain human flu viruses and avian flu viruses can also use a second entry pathway, a protein complex of the immune system, to infect cells. This ability helps the viruses infect different species -- and potentially jump between animals and humans.

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Snot might not be the first place you'd expect nanobots to be swimming around. But this slimy secretion exists in more places than just your nose and piles of dirty tissues -- it also lines and helps protect the lungs, stomach, intestines and eyes. And now, researchers have demonstrated in mice that their tiny, enzyme-powered 'snot bots' can push through the defensive, sticky layer and potentially deliver drugs more efficiently.

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CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy.

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Delivery systems in body continuously move materials between cells. Hijacking these systems allowed scientists to improve loading and delivery of therapeutic proteins. Biophysical principles could be used to enable more cost-effective loading of biological cargo into cell-derived delivery systems. Engineered molecules loaded up to 240 times more protein than other loading methods.

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Research achieves scientific breakthrough in understanding cell division.

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Our immune system is always on alert, detecting and eliminating pathogens and cancer cells. Cellular control mechanisms cause diseased cells to present antigens on their surface like signs for the immune system. For analysis of the necessary complex antigen processing and transport processes in real time, researchers have developed a 'cage' that is opened with light to release trapped antigens at a specific place and time.

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Researchers have discovered that a single-celled organism, a close relative of animals, harbors the remnants of ancient giant viruses woven into its own genetic code. This finding sheds light on how complex organisms may have acquired some of their genes and highlights the dynamic interplay between viruses and their hosts.

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Carbon capture is a promising approach for mitigating carbon dioxide (CO2) emissions. Different materials have been used to capture CO2 from industrial exhaust gases. Scientists developed hybrid CO2 capture materials containing sodium carbonate and nanocarbon prepared at different temperatures, tested their performance, and identified the optimal calcination temperature condition. They found that the hybrid material exhibits and maintains high CO2 capture capacity for multiple regeneration cycles at a lower temperature, making it cost- and energy-effective.

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New research shows that ozone concentrations at Carlsbad Caverns National Park frequently exceed Environmental Protection Agency health standards, likely due to oil and natural gas development in the Permian Basin and surrounding region.

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Researchers studying antimicrobial-resistant E. coli -- the leading cause of human death due to antimicrobial resistance worldwide -- have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.

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A new study has unveiled surprising findings about mercury pollution: where it comes from and how it moves through the environment vary significantly depending on the ecosystem. In drier regions, most mercury is deposited through rain and snow. In wetter, forested areas, gaseous mercury from the air sticks to leaves, which then fall and carry the toxin into the ground.

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Nitrogen fertilizers make it possible to feed the world's growing population, but they are also costly adn harm ecosystems. However, a few plants have evolved the ability to acquire their own nitrogen with the help of bacteria, and a new study helps explain how they did it, not once, but multiple times.

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Researchers grew crystals containing actinium and illuminated them with X-rays to learn how the radioactive metal binds with other elements. That information could help design better cancer treatments.

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A study opens new possibilities to improve production efficiency in the cattle industry and potentially animal agriculture more broadly.

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Researchers have successfully developed an environmentally friendly, microspherical fluorescent material primarily made from citric acid. These microbeads emit various colors of light depending on the illuminating light and the size of the beads, which suggests a wide range of applications. Furthermore, the use of plant-derived materials allows for low-cost and energy-efficient synthesis.