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Categories: Biology: Genetics, Chemistry: Biochemistry
Published Scientists discover new behavior of membranes that could lead to unprecedented separations



Argonne scientists have used isoporous membranes -- membranes with pores of equal size and shape -- and recirculation to create separations at the nanoscale that overcome previous limitations.
Published Scientists devise algorithm to engineer improved enzymes



Scientists have prototyped a new method for 'rationally engineering' enzymes to deliver improved performance. They have devised an algorithm, which takes into account an enzyme's evolutionary history, to flag where mutations could be introduced with a high likelihood of delivering functional improvements. Their work could have significant, wide-ranging impacts across a suite of industries, from food production to human health.
Published Creation of a power-generating, gel electret-based device



A team of researchers has developed a gel electret capable of stably retaining a large electrostatic charge. The team then combined this gel with highly flexible electrodes to create a sensor capable of perceiving low-frequency vibrations (e.g., vibrations generated by human motion) and converting them into output voltage signals. This device may potentially be used as a wearable healthcare sensor.
Published Wild yeasts from Patagonia could yield new flavors of lagers



New strains of yeast for brewing lager beers, created by hybridizing wild strains of yeast from Patagonia with brewer's yeast, can yield novel flavors and aromas, researchers report.
Published Transforming inexpensive quinolines into complex drug candidates



An innovative synthesis strategy opened up the way to 2D/3D fused frameworks using inexpensive quinolines as feedstock, report scientists. By leveraging a light-sensitive borate intermediate, the scientists could transform quinoline derivatives into a great variety of 2D/3D fused frameworks in a straightforward and cost-effective manner. Their findings are expected to enable the synthesis of highly customizable drug candidates.
Published A railroad of cells



Looking under the microscope, a group of cells slowly moves forward in a line, like a train on the tracks. The cells navigate through complex environments. A new approach now shows how they do this and how they interact with each other.
Published Much of the Nord Stream gas remained in the sea



Much of the methane released into the southern Baltic Sea from the Nord Stream gas pipeline has remained in the water. This is shown by measurements taken by researchers from the University of Gothenburg.
Published New technology provides electrifying insights into how catalysts work at the atomic level



A team has invented a technique to study electrochemical processes at the atomic level with unprecedented resolution. They have already used it to discover a surprising phenomena in a popular catalyst material and plan to apply their technology to studying a wide variety of electrochemical systems including batteries, fuel cells, and solar fuel generators. The insights could lead to more efficient and durable devices.
Published Researchers create new class of materials called 'glassy gels'



Researchers have created a new class of materials called 'glassy gels' that are very hard and difficult to break despite containing more than 50% liquid. Coupled with the fact that glassy gels are simple to produce, the material holds promise for a variety of applications.
Published Mirror-image chemicals may revolutionize drug delivery



More than 130 years after cyclodextrins were first discovered and reported, a team of scientists has created chemical mirror images of these complex carbohydrates in the laboratory. This discovery may revolutionize how medications are delivered to patients.
Published Is coffee good for you or bad for you?



The effects of coffee consumption on human health is a knotty question, but one thing is sure: coffee is a psychoactive substance.
Published How targeted nutrients can fight cancer



An international research team has discovered a new way to effectively treat cancer, by using nutrients to reactivate suppressed metabolic pathways in cancer cells.
Published Unveiling Telo-seq: A breakthrough in telomere research on aging and cancer



Telo-seq -- a new tool -- is bringing telomere science into its modern era. Scientists can finally explore questions about the role of telomeres in aging and cancer that were not accessible with previous methods. The findings will inspire novel telomere-targeting therapeutics for aging-related diseases.
Published Where to put head and tail?



Formation of the body axes is a critical part of embryonic development. They guarantee that all body parts end up where they belong and that no ears grow on our backs. The head-tail axis, for example, determines the orientation of the two ends of the body. It was previously assumed that this axis is largely determined by the interplay between the Nodal and BMP signals. However, there appears to be another player in this system, as researchers have now discovered by using an embryo-like model system they developed. In the absence of BMP, the signalling molecule beta-catenin takes on the role of the Nodal antagonist. This new mechanism could be a flexible solution for axis formation in embryos with different shapes.
Published How the ketogenic diet improves healthspan and memory in aging mice



The ketogenic diet has its fanatics and detractors among dieters, but either way, the diet has a scientifically documented impact on memory in mice. While uncovering how the high fat, low carbohydrate diet boosts memory in older mice, scientists identified a new molecular signaling pathway that improves synapse function and helps explain the diet's benefit on brain health and aging.
Published Custom-made molecules designed to be invisible while absorbing near-infrared light



Researchers used theoretical calculations assessing electron orbital symmetry to synthesize new molecule designed to be both transparent and colorless while absorbing near-infrared light. This compound demonstrates the first systematic approach to producing such materials and have applications in advanced electronics. This compound also shows semiconducting properties.
Published Molecular sponge for the electronics of the future



An international research team has succeeded in developing a new type of material in the rather young research field of covalent organic frameworks. The new two-dimensional polymer is characterized by the fact that its properties can be controlled in a targeted and reversible manner. This has brought the researchers a step closer to the goal of realizing switchable quantum states.
Published Finding hidden genetic treasure: Study uncovers untapped diversity in historic wheat collection



A decade-long study has discovered huge genetic potential that is untapped in modern wheat varieties.
Published Breakthrough approach enables bidirectional BCI functionality



Brain-computer interfaces or BCIs hold immense potential for individuals with a wide range of neurological conditions, but the road to implementation is long and nuanced for both the invasive and noninvasive versions of the technology. Scientists have now successfully integrated a novel focused ultrasound stimulation to realize bidirectional BCI that both encodes and decodes brain waves using machine learning in a study with 25 human subjects. This work opens up a new avenue to significantly enhance not only the signal quality, but also, overall nonivasive BCI performance by stimulating targeted neural circuits.
Published Some CRISPR screens may be missing cancer drug targets



CRISPR/Cas9 gene editing has made possible a multitude of biomedical experiments including studies that systematically turn off genes in cancer cells to look for ones that the cancer cells heavily depend on to survive and grow. These genes, or 'cancer dependencies,' are often promising drug targets. But new research shows that many of these CRISPR screening experiments rely on components, called CRISPR/Cas9 guides, that do not perform equally well in cells from people of all ancestries, which can cause CRISPR screens to miss cancer dependencies.