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Categories: Biology: Genetics, Chemistry: Biochemistry

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Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

New, modified CRISPR protein can fit inside virus used for gene therapy      (via sciencedaily.com)     Original source 

Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.

Chemistry: Biochemistry
Published

Portable pathology passes the test      (via sciencedaily.com)     Original source 

On-site pathology tests for infectious diseases in rural and remote locations can be just as reliable and accurate as tests carried out in a hospital laboratory, a new report shows.

Chemistry: Biochemistry Chemistry: Inorganic Chemistry Physics: General
Published

Combining simulations and experiments to get the best out of Fe3Al      (via sciencedaily.com)     Original source 

Researchers combined computer simulations and transmission electron microscopy experiments to better understand the ordering mobility and formation of microstructure domains in Fe3Al alloy. They were able to correlate structural changes with heat treatment to understand how particular mechanical behavior can be achieved. This is expected to allow the superelastic properties of Fe3Al to harnessed for the 3D printing of construction materials for absorbing seismic activity.

Biology: Biochemistry Biology: Biotechnology Biology: Botany Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Ecology: Endangered Species Geoscience: Geochemistry
Published

Researchers expose new symbiosis origin theories, identify experimental systems for plant life      (via sciencedaily.com)     Original source 

Research work on symbiosis -- a mutually beneficial relationship between living organisms -- is pushing back against the newer theory of a 'single-origin' of root nodule symbiosis (RNS) -- that all symbiosis between plant root nodules and nitrogen-fixing bacteria stems from one point--instead suggesting a 'multiple-origin' theory of sybiosis which opens a better understanding for genetically engineering crops.

Chemistry: Biochemistry
Published

AIM algorithm enhances super-resolution microscope images in real time      (via sciencedaily.com)     Original source 

When trying to measure molecular structures with nanometer precision, every bit of noise shows up in the data: someone walking past the microscope, tiny vibrations in the building and even the traffic outside. A new processing technique removes noise from optical microscope data in real time, allowing scientists to track individual molecules over 10 times more precisely than was possible before.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

hnRNPM, a guardian of the integrity of cellular protein production      (via sciencedaily.com)     Original source 

Researchers have discovered that the protein hnRNPM prevents the cell from making mistakes while it is producing new proteins, which helps maintain the integrity of this vital process.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Chemistry: Biochemistry Chemistry: Organic Chemistry
Published

Editing without 'cutting': Molecular mechanisms of new gene-editing tool revealed      (via sciencedaily.com)     Original source 

New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a 'prime editor' could achieve reverse transcription, synthesizing DNA from RNA, without 'cutting' both strands of the double helix. Clarifying these molecular mechanisms contributes greatly to designing gene-editing tools accurate enough for gene therapy treatments.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular Offbeat: General Offbeat: Plants and Animals
Published

Chicken feathers to deliver chemotherapy drugs and repair enzymes      (via sciencedaily.com)     Original source 

A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.

Biology: Biochemistry Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics
Published

Complete X and Y chromosome sequences of living great ape species determined      (via sciencedaily.com)     Original source 

Newly generated, complete genomes for the sex chromosomes of six primate species may inform conservation of these endangered species and shed light on sex-related genetic diseases in both humans and our closest living relatives.

Chemistry: Biochemistry Engineering: Robotics Research Offbeat: Computers and Math Offbeat: General
Published

Public have no difficulty getting to grips with an extra thumb, study finds      (via sciencedaily.com)     Original source 

Researchers have shown that members of the public have little trouble in learning very quickly how to use a third thumb -- a controllable, prosthetic extra thumb -- to pick up and manipulate objects. The team tested the robotic device on a diverse range of participants, which they say is essential for ensuring new technologies are inclusive and can work for everyone.

Chemistry: Biochemistry Chemistry: General Chemistry: Inorganic Chemistry Energy: Batteries
Published

Polymeric films protect anodes from sulfide solid electrolytes      (via sciencedaily.com)     Original source 

Researchers unveil the interaction between polymeric materials and sulfide solid electrolytes.

Biology: Biochemistry Biology: Botany Biology: Cell Biology Biology: General Biology: Genetics Ecology: Endangered Species
Published

Scientists identify gene that could lead to resilient 'pixie' corn      (via sciencedaily.com)     Original source 

A widely found gene in plants has been newly identified as a key transporter of a hormone that influences the size of corn. The discovery offers plant breeders a new tool to develop desirable dwarf varieties that could enhance the crop's resilience and profitability.

Anthropology: Early Humans Anthropology: General Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Evolutionary Biology: General Biology: Genetics Biology: Zoology Ecology: Extinction Paleontology: Early Mammals and Birds Paleontology: Fossils Paleontology: General
Published

Bringing back an ancient bird      (via sciencedaily.com)     Original source 

Using ancient DNA extracted from the toe bone of a museum specimen, biologists have sequenced the genome of an extinct, flightless bird called the little bush moa, shedding light into an unknown corner of avian genetic history. The work is the first complete genetic map of the turkey-sized bird whose distant living cousins include the ostrich, emu, and kiwi.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Mechanisms for selective multiple sclerosis treatment strategy      (via sciencedaily.com)     Original source 

Researchers have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: General Biology: Genetics Biology: Molecular
Published

'Cloaked' proteins deliver cancer-killing therapeutics into cells      (via sciencedaily.com)     Original source 

Scientists have designed a way to 'cloak' proteins in a generalized technique that could lead to repurposing things like antibodies for biological research and therapeutic applications.

Biology: Biochemistry Biology: Biotechnology Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Biology: Microbiology Biology: Molecular
Published

Genetic mosaicism more common than thought      (via sciencedaily.com)     Original source 

Researchers found that approximately one in 40 human bone marrow cells carry massive chromosomal alterations without causing any apparent disease or abnormality. Even so-called normal cells carry all sorts of genetic mutations, meaning there are more genetic differences between individual cells in our bodies than between different human beings. The discovery was enabled by a single-cell sequencing technology called Strand-seq, a unique DNA sequencing technique that can reveal subtle details of genomes in single cells that are too difficult to detect with other methods.

Biology: Biochemistry Biology: Cell Biology Biology: Developmental Biology: Evolutionary Biology: General Biology: Genetics Offbeat: Earth and Climate Offbeat: General Offbeat: Paleontology and Archeology Offbeat: Plants and Animals
Published

How killifish embryos use suspended animation to survive over 8 months of drought      (via sciencedaily.com)     Original source 

The African turquoise killifish lives in ephemeral ponds in Zimbabwe and Mozambique. To survive the annual dry season, the fish's embryos enter a state of extreme suspended animation or 'diapause' for approximately 8 months. Now, researchers have uncovered the mechanisms that enabled the killifish to evolve this extreme survival state.

Biology: Biochemistry Biology: Botany Chemistry: Biochemistry Ecology: Endangered Species Ecology: Nature Energy: Technology
Published

Harnessing green energy from plants depends on their circadian rhythms      (via sciencedaily.com)     Original source 

Plant hydraulics drive the biological process that moves fluids from roots to plant stems and leaves, creating streaming electric potential, or voltage, in the process. A study closely examined the differences in voltage caused by the concentrations of ions, types of ions, and pH of the fluid plants transport, tying the voltage changes to the plant's circadian rhythm that causes adjustments day and night. According to the authors, this consistent, cyclic voltage creation could be harnessed as an energy source.

Biology: Biochemistry Biology: Developmental Biology: General Biology: Genetics Biology: Marine Environmental: General Geoscience: Environmental Issues Geoscience: Geochemistry
Published

Investigating the origin of circatidal rhythms in freshwater snails      (via sciencedaily.com)     Original source 

While most organisms have biological clocks synchronized with the day-night cycle (circadian rhythms), marine animals in tidal areas have also developed circatidal rhythms to align with the tidal cycle. Comparing the activity and genetic expression of snails from tidal and non-tidal areas, researchers demonstrate that circatidal rhythms develop as snails adapt to tidal environments. These findings highlight the flexibility of biological clocks, enabling organisms to adjust their rhythms according to the environment.