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Categories: Biology: Genetics, Chemistry: Biochemistry

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Undergoing surgery is seldom a pleasant experience, and it can sometimes be highly invasive. Surgical procedures have evolved steadily over the centuries, growing with the knowledge of anatomy and biology. Innovative methods have also been bolstered with new tools, and a growth in the use of robotics since the 1980s has moved health care forward significantly.

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Researchers have outlined a way to manipulate water molecules to make CO2R more efficient, with the ultimate goal of creating a clean energy loop. Through their new method, the team was able to perform CO2R with nearly 100% efficiency under mildly acidic conditions, using either gold or zinc as catalysts.

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Researchers have developed a new technique to view living mammalian cells. The team used a powerful laser, called a soft X-ray free electron laser, to emit ultrafast pulses of illumination at the speed of femtoseconds, or quadrillionths of a second. With this they could capture images of carbon-based structures in living cells for the first time, before the soft X-ray radiation damaged them.

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In an interdisciplinary study, researchers discovered that symbiotic bacteria communicate with legume plants through specific molecules and that this communication influences which bacteria grow near the plant roots. The findings provide insights into how plants and soil bacteria form beneficial partnerships for nutrient uptake and resilience. These results are a step towards understanding how communication between plants and soil bacteria can lead to specific beneficial associations providing plants with nutrients.

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Biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new 'gene atlas' with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.

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From soil to sequestration, researchers have modeled what a supply chain for second-generation biofuels might look like in the midwestern United States.

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A research team developed an interactive multi-stage robotic positioner specifically designed for magnetic resonance imaging (MRI)-guided stereotactic neurosurgery.

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Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing.

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In a recent study, researchers developed modified norcorrole molecules whose side chains favored the formation of columnar -stacking structures. Using these compounds, they produced liquid crystals with high electrical conductivity and thermotropic properties. Their findings open up new design avenues for materials useful in electronics, sensing, optics, and biomedicine.

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Treatment of autoimmune diseases like lupus has long relied on steroids to knock down the immune system, but more targeted therapies are currently undergoing clinical trials. To make sure these therapies get to the patients who will benefit, work is needed to identify the specific mutations behind each patient's disease. Researchers now report several dozen mutations associated with oversensitive toll-like receptors -- a major cause of autoimmune disease -- and linked two mutations to patients.

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Members of the vertebrate group including anglerfishes are unique in possessing a characteristic known as sexual parasitism, in which males temporarily attach or permanently fuse with females to mate. Now, researchers show that sexual parasitism arose during a time of major global warming and rapid transition for anglerfishes from the ocean floor to the deep, open sea.

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A study has discovered molecular pathways regulated by a gene traditionally used to control wheat-flowering behavior could be altered to achieve greater yields.

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An international team have developed a new material that moves like skin while preserving signal strength in electronics. The technology could enable the development of next-generation wearable devices with continuous, consistent wireless and battery-free functionality.

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Engineers have developed a wearable ultrasound patch that can offer continuous, non-invasive monitoring of blood flow in the brain. The soft and stretchy patch can be comfortably worn on the temple to provide three-dimensional data on cerebral blood flow--a first in wearable technology.

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Researchers developed a way to help people with amputation or paralysis regain limb control. Their optogenetic technique could offer more precise control over muscle contraction, along with a dramatic decrease in muscle fatigue.

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Animals and fungi predominantly use two different modes of cell division -- called open and closed mitosis, respectively. A new study has shown that different species of Ichthyosporea -- marine protists that are close relatives of both animals and fungi -- use either open and closed mitosis, closely correlated to whether the species has multinucleate life cycle stages. The study demonstrates the way animals do cell division might have evolved long before animals themselves did and how this is linked to an organism's life cycle.

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Researchers found that adding a newly developed modified sugar, BNAP-AEO, to gapmer antisense oligonucleotides (ASOs) increased their affinity for target RNAs, thus significantly enhancing their gene-silencing effects in vitro and in vivo. The BNAP-AEO modification also decreased gapmer ASO toxicity to the central nervous system (CNS), suggesting that it could improve the clinical application of ASO treatment of CNS disease.

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Researchers have used computational design methods to develop non-metal organic porous framework materials, with potential applications in areas such as catalysis, water capture or hydrogen storage.

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Engineers have found a way to eliminate the buildup of scar tissue around implantable devices, by coating them with a hydrogel adhesive. The material binds the device to tissue and prevents the immune system from attacking the device.

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Scientists have uncovered the properties of a rare earth element that was first discovered 80 years ago at the very same laboratory, opening a new pathway for the exploration of elements critical in modern technology, from medicine to space travel.