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Categories: Biology: Genetics, Chemistry: Biochemistry

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The length of telomeres in white blood cells, known as leukocytes, varies significantly among sub-Saharan African populations, researchers report. Moreover, leukocyte telomere length (LTL) is negatively associated with malaria endemicity and only partly explained by genetic factors.

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Researchers have developed a unique shape-tunable mirror that can change shape to optimally channel X-rays. It is composed of a single crystal of lithium niobate. This new technology offers the ability to correct aberration in the X-ray region, leading to improved spatial resolution.

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A parasite that not only feeds of its host, but also makes the host change its own metabolism and thus biology. Microbiologists have shown this for the very first time in a specific group of parasitic microbes, so-called DPANN archea. Their study shows that these archaea are very 'picky eaters', which might drive their hosts to change the menu.

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Viruses known as 'jumbo' phages are seen as a potential tool against deadly bacterial infections. But scientists must first decipher the extraordinary makeup of these mysterious viruses. Researchers have now uncovered a key piece of jumbo phage development that helps them counter bacteria.

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Scientists are harnessing cells to make new types of materials that can grow, repair themselves and even respond to their environment. These solid 'engineered living materials' are made by embedding cells in an inanimate matrix that's formed in a desired shape. Now, researchers have 3D printed a bioink containing plant cells that were then genetically modified, producing programmable materials. Applications could someday include biomanufacturing and sustainable construction.

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Conventional plant regeneration approaches by cell culture require the external application of plant growth regulators, including hormones. However, optimizing culture conditions can be laborious. Now, researchers have developed a novel plant regeneration system that omits the need for hormone application by genetically regulating the expression of genes that control plant cell differentiation. Their work holds significant potential in the development of genetically modified plants in a simpler and cost-effective manner.

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Common household products containing nanoparticles -- grains of engineered material so miniscule they are invisible to the eye -- could be contributing to a new form of indoor air pollution, according to a new study.

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Organic electrochemical transistors (OECTs) allow current to flow in devices like implantable biosensors. But scientists long knew about a quirk of OECTs that no one could explain: When an OECT is switched on, there is a lag before current reaches the desired operational level. When switched off, there is no lag. Current drops immediately. Researchers report that they have discovered the reason for this activation lag, and in the process are paving the way to custom-tailored OECTs for a growing list of applications in biosensing, brain-inspired computation and beyond.

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Researchers have developed a chemical process using plasma that could create sustainable jet fuel from methane gas emitted from landfills, potentially creating a low-carbon aviation industry.

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Scientists report significant progress in cultivating nephron progenitor cells (NPCs), the cells destined to form the kidney's filtration system, the nephrons. NPCs hold immense promise for understanding kidney development, modeling diseases, and discovering new treatments. The team improved the chemical cocktail for generating and growing NPCs in the laboratory, enabling the sustained growth of both mouse and human NPCs in a simple 2-dimensional format.

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A new type of bioplastic could help reduce the plastic industry's environmental footprint. Researchers have developed a biodegradable form of thermoplastic polyurethane (TPU) filled with bacterial spores that, when exposed to nutrients present in compost, germinate and break down the material at the end of its life cycle.

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Researchers have discovered a new mechanism of oil biosynthesis and found a way to genetically engineer a type of test plant to more efficiently produce different kinds of seed oil that it otherwise wouldn't make. While the engineering is proof-of-concept, this discovery could lead to improved production of valuable oils used in food and by a range of industries. The modified plant overcame metabolic bottlenecks and produced significant amounts of an oil similar to castor oil that it doesn't naturally produce.

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Researchers have achieved a breakthrough in understanding how genetic drivers influence the evolution of a specific photosynthesis mechanism in Tillandsia (air plants). This sheds light on the complex actions that cause plant adaptation and ecological diversity.

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A four-legged robot trained with machine learning has learned to avoid falls by spontaneously switching between walking, trotting, and pronking -- a milestone for roboticists as well as biologists interested in animal locomotion.

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The research explores how CRISPR can be used to edit RNA.

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A new study uncovers a switchable, atomically-thin metal-organic material that could be used in future low-energy electronic technologies. The study shows that electron interactions in this material create an unusual electrically-insulating phase in which electrons are 'frozen'. By reducing the population of electrons, the authors are able to unfreeze the remaining electrons, allowing for controlled transitions between insulating and electrically-conductive phases: the key to the on-off binary operations of classical computing.

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Researchers report on the molecular assembly of one of the most common anti-phage systems -- from the family of proteins called Gabija -- that is estimated to be used by at least 8.5%, and up to 18%, of all bacteria species on Earth.

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Researchers have demonstrated that ferromagnetism, an ordered state of atoms, can be induced by increasing particle motility and that repulsive forces between atoms are sufficient to maintain it. The discovery not only extends the concept of active matter to quantum systems but also contributes to the development of novel technologies that rely on the magnetic properties of particles, such as magnetic memory and quantum computing.

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Researchers outline how they used a chemical probe to light up interlocking peptides. Their technique will help scientists differentiate synthetic peptides from toxic types found in Alzheimer's disease.

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Researchers have created TopicVelo, a powerful new method of using the static snapshots from scRNA-seq to study how cells and genes change over time. This will help researchers better study how embryos develop, cells differentiate, cancers form, and the immune system reacts.