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Categories: Biology: Genetics, Chemistry: Biochemistry

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Researchers have identified how the tick-borne Crimean-Congo haemorrhagic fever virus enters our cells. The results are an important step in the development of drugs against the deadly disease.

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Through DNA sequencing of Tasmanian devils and their tumors, researchers have tracked the genomic interactions between the animals and the cancer.

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Barley is one of the most important cereal crops on a global scale. Many barley cultivars produce a toxic alkaloid called gramine that affects the suitability of barley as fodder, but also helps to protect barley from pathogens. So far, the potential of manipulating gramine levels has not been harnessed for plant breeding, because the genetic basis of gramine production has been unresolved. Research groups now disclose the complete biosynthetic pathway of gramine and demonstrate how gramine biosynthesis can be introduced into model organisms or removed from barley.

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Analysing the diversity of organic compounds dissolved in freshwater provides a reliable measure of ecosystem health, say scientists.

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Biologists have uncovered a quality control timing mechanism tied to cell division. The 'stopwatch' function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.

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Branching patterns are prevalent in our natural environment and the human body, such as in the lungs and kidneys. For example, specific genes that express growth factor proteins are known to influence the development of the lungs' complex branches. Researchers have unveiled a regulatory system linking signal, force, and shape in mouse lung structure development. The team recognized that the signal protein ERK plays an active role in causing growing lung tissue to curve.

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A research team has addressed the long-standing challenge of creating artificial olfactory sensors with arrays of diverse high-performance gas sensors. Their newly developed biomimetic olfactory chips (BOC) are able to integrate nanotube sensor arrays on nanoporous substrates with up to 10,000 individually addressable gas sensors per chip, a configuration that is similar to how olfaction works for humans and other animals.

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Engineers designed an 'architected' reef that can mimic the wave-buffering effects of natural reefs while providing pockets for marine life. The sustainable and cost-saving structure could dissipate more than 95 percent of incoming wave energy using a small fraction of the material normally needed.

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What would you do if you walked up to a robot with a human-like head and it smiled at you first? You'd likely smile back and perhaps feel the two of you were genuinely interacting. But how does a robot know how to do this? Or a better question, how does it know to get you to smile back?

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Scientists created a highly accurate reference genome for one of the most important modern crops and found a rare example of how genes confer disease resistance in plants. Exploring sugarcane's genetic code could help researchers develop more resilient and productive crops, with implications for both sugar production and biofuels.

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Researchers have recovered remarkably preserved microbiomes from two teeth dating back 4,000 years, found in an Irish limestone cave. Genetic analyses of these microbiomes reveal major changes in the oral microenvironment from the Bronze Age to today. The teeth both belonged to the same male individual and also provided a snapshot of his oral health.

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Understanding the structure of proteins is critical for demystifying their functions and developing drugs that target them. To that end, a team of researchers has developed a way of using machine learning to rapidly predict multiple protein configurations to advance understanding of protein dynamics and functions.

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Researchers are enhancing immunotherapy effects against malignant tumors by developing and validating patent-ending poly (lactic-co-glycolic acid), or PLGA, nanoparticles modified with adenosine triphosphate, or ATP.

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A study is the first to evaluate substrate recolonization by sponges in the U.S. Virgin Islands after two catastrophic storms using genetic analyses to understand how much clonality verses sexual recruitment occurs on coral reefs post-storms. Results show that populations of clonal marine species with low pelagic dispersion, such as A. cauliformis, may benefit from increased frequency and magnitude of hurricanes to maintain genetic diversity and combat inbreeding, enhancing the resilience of Caribbean sponge communities to extreme storm events.

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Entropy, the amount of molecular disorder, is produced in several systems but cannot be measured directly. A new equation sheds new light on how entropy is produced on a very short time scale in laser excited materials.

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An international research team has designed and manufactured a virus-killing surface that could help control disease spread in hospitals, labs and other high-risk environments.

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Scientists have uncovered a unique mechanism that regulates the opening of stomata in plants. Phosphorylation of the amino acid Thr881 on the plasma membrane proton pump plays a key role in this process. The study paves the way for the targeted manipulation of plant physiology, with potential applications in agriculture and environmental sustainability.

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Pushing for a higher speed isn't just for athletes. Researchers, too, can achieve such feats with their discoveries. A new device called SCARF (for swept-coded aperture real-time femtophotography) can capture transient absorption in a semiconductor and ultrafast demagnetization of a metal alloy. This new method will help push forward the frontiers of knowledge in a wide range of fields, including modern physics, biology, chemistry, materials science, and engineering.

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Humans pass on more viruses to domestic and wild animals than we catch from them, according to a major new analysis of viral genomes.

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Biologists use a novel method of simultaneous acoustic tagging to gain insights into the link between whale communication and behavior