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Categories: Biology: Evolutionary, Chemistry: Organic Chemistry
Published New understanding of ancient genetic parasite may spur medical breakthroughs
(via sciencedaily.com) Original source Researchers have determined the structure of the most common material in our genomes. New treatments for autoimmune diseases, cancer and neurodegeneration may follow.
Published Enzymes can't tell artificial DNA from the real thing
(via sciencedaily.com) Original source Researchers have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
Published Nanoprobe with a barcode
(via sciencedaily.com) Original source Protein-splitting enzymes play an important role in many physiological processes. Such proteases are generally present in an inactive state, only becoming activated under certain conditions. Some are linked to diseases like infections or cancer, making it important to have methods that can selectively detect active proteases. Scientists have introduced a new class of protease-activity sensors: gold nanoparticles equipped with peptide DNA.
Published Cell types in the eye have ancient evolutionary origins
(via sciencedaily.com) Original source In a comparative analysis across vertebrates of the many cell types in the retina -- mice alone have 130 types -- researchers concluded that most cell types have an ancient evolutionary history. Their remarkable conservation across species suggests that the retina of the last common ancestor of all mammals, which roamed the earth some 200 million year ago, must have had a complexity rivaling the retina of modern mammals.
Published Nanoparticle-delivered RNA reduces neuroinflammation in lab tests
(via sciencedaily.com) Original source In mice and human cell cultures, researchers showed that novel nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer's disease.
Published First observation of structures resulting from 3D domain swapping in antibody light chains
(via sciencedaily.com) Original source Antibodies hold promise as therapeutic agents. However, their tendency to aggregate poses significant challenges to drug development. In a groundbreaking study, researchers now provide novel insights into the structure formed due to 3D domain swapping of the antibody light chain, the part of the antibody contributing to antigen binding. Their findings are expected to lead to improvements in antibody quality and the development of novel drugs.
Published New genes can arise from nothing
(via sciencedaily.com) Original source The complexity of living organisms is encoded within their genes, but where do these genes come from? Researchers resolved outstanding questions regarding the origin of small regulatory genes, and described a mechanism that creates their DNA palindromes. Under suitable circumstances, these palindromes evolve into microRNA genes.
Published A fork in the 'rhod': Researchers unveil comprehensive collection of rhodamine-based fluorescent dyes
(via sciencedaily.com) Original source After more than a decade of developing fluorescent probes, a research team has now released the culmination of their years of work: A comprehensive collection of rhodamine-based dyes, the novel chemistry they developed to synthesize them and insights that provide a roadmap for designing future probes.
Published Molecular fossils shed light on ancient life
(via sciencedaily.com) Original source Paleontologists are getting a glimpse at life over a billion years in the past based on chemical traces in ancient rocks and the genetics of living animals. New research combines geology and genetics, showing how changes in the early Earth prompted a shift in how animals eat.
Published Chemists create organic molecules in a rainbow of colors
(via sciencedaily.com) Original source Chemists have now come up with a way to make molecules known as acenes more stable, allowing them to synthesize acenes of varying lengths. Using their new approach, they were able to build molecules that emit red, orange, yellow, green, or blue light, which could make acenes easier to deploy in a variety of applications.
Published From infamy to ingenuity: Bacterial hijack mechanisms as advanced genetic tools
(via sciencedaily.com) Original source Researchers have uncovered the intricate molecular mechanism used by parasitic phytoplasma bacteria, known for inducing 'zombie-like' effects in plants.
Published Researchers decode aqueous amino acid's potential for direct air capture of CO2
(via sciencedaily.com) Original source Scientists have made a significant stride toward understanding a viable process for direct air capture, or DAC, of carbon dioxide from the atmosphere. This DAC process is in early development with the aim of achieving negative emissions, where the amount of carbon dioxide removed from the envelope of gases surrounding Earth exceeds the amount emitted.
Published Earliest-known fossil mosquito suggests males were bloodsuckers too
(via sciencedaily.com) Original source Researchers have found the earliest-known fossil mosquito in Lower Cretaceous amber from Lebanon. What's more, the well-preserved insects are two males of the same species with piercing mouthparts, suggesting they likely sucked blood. That's noteworthy because, among modern-day mosquitoes, only females are hematophagous, meaning that they use piercing mouthparts to feed on the blood of people and other animals.
Published Crocodile family tree mapped: New light shed on croc evolution
(via sciencedaily.com) Original source Around 250 million years ago, 700 species of reptiles closely related to the modern-day crocodile roamed the earth, now new research reveals how a complex interplay between climate change, species competition and habitat can help explain why just 23 species of crocodile survive today.
Published New technique efficiently offers insight into gene regulation
(via sciencedaily.com) Original source Researchers have developed a new technique called MAbID. This allows them to simultaneously study different mechanisms of gene regulation, which plays a major role in development and disease. MAbID offers new insights into how these mechanisms work together or against each other.
Published PicoRuler: Molecular rulers for high-resolution microscopy
(via sciencedaily.com) Original source A team presents a groundbreaking advance for the world of high-resolution fluorescence microscopy: The innovative method enables researchers for the first time to use biomolecules as molecular rulers to calibrate the latest super-resolution microscopy methods, which have a resolution of just a few nanometers.
Published Genomic study sheds light on how carnivorous Asian pitcher plants acquired signature insect trap
(via sciencedaily.com) Original source Scientists sequenced the genome of the East Asian pitcher plant, Nepenthes gracilis, a species of carnivorous plant related to Venus flytraps, as well as sundews, beets and spinach.
Published Researchers reveal new process for making anhydride chemical compounds
(via sciencedaily.com) Original source A collaborative research team has discovered a new process for making anhydrides that promises improvements in costs and sustainability.
Published Snake skulls show how species adapt to prey
(via sciencedaily.com) Original source By studying the skull shapes of dipsadine snakes, researchers have found how these species of snakes in Central and South America have evolved and adapted to meet the demands of their habitats and food sources.
Published A mixed origin made maize successful
(via sciencedaily.com) Original source Maize is one of the world's most widely grown crops. It is used for both human and animal foods and holds great cultural significance, especially for indigenous peoples in the Americas. Yet despite its importance, the origins of the grain have been hotly debated for more than a century. Now new research shows that all modern maize descends from a hybrid created just over 5000 years ago in central Mexico, thousands of years after the plant was first domesticated.