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Categories: Biology: Evolutionary, Chemistry: Organic Chemistry
Published Ancient viruses fuel modern-day cancers
(via sciencedaily.com) Original source The human genome is filled with flecks of DNA left behind by viruses that infected primate ancestors tens of millions of years ago. Scientists used to think they were harmless, but new research shows that, when reawakened, they help cancer survive and thrive.
Published Discovery of a hybrid lineage offers clues to how trees adapt to climate change
(via sciencedaily.com) Original source The discovery of a hybrid population of poplar trees in western Wyoming has provided insight into how natural hybridization informs the evolution of many plant species, according to researchers. They also said their discovery suggests that genetic exchange between species may be critical for adaptation to environmental change.
Published A new addition to the CRISPR toolbox: Teaching the gene scissors to detect RNA
(via sciencedaily.com) Original source CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel method, called PUMA, enables the detection of RNA with Cas12 nucleases, which naturally target DNA. PUMA promises a wide range of applications and high accuracy.
Published Transporting precious cargo using the body's own delivery system
(via sciencedaily.com) Original source Delivery systems in body continuously move materials between cells. Hijacking these systems allowed scientists to improve loading and delivery of therapeutic proteins. Biophysical principles could be used to enable more cost-effective loading of biological cargo into cell-derived delivery systems. Engineered molecules loaded up to 240 times more protein than other loading methods.
Published Ancient microbes offer clues to how complex life evolved
(via sciencedaily.com) Original source Researchers have discovered that a single-celled organism, a close relative of animals, harbors the remnants of ancient giant viruses woven into its own genetic code. This finding sheds light on how complex organisms may have acquired some of their genes and highlights the dynamic interplay between viruses and their hosts.
Published E. coli variant may cause antimicrobial resistance in dogs, humans
(via sciencedaily.com) Original source Researchers studying antimicrobial-resistant E. coli -- the leading cause of human death due to antimicrobial resistance worldwide -- have identified a mechanism in dogs that may render multiple antibiotic classes ineffective.
Published Unlocking the mystery of preexisting drug resistance: New study sheds light on cancer evolution
(via sciencedaily.com) Original source The evolution of resistance to diseases, from infectious illnesses to cancers, poses a formidable challenge. Despite the expectation that resistance-conferring mutations would dwindle in the absence of treatment due to a reduced growth rate, preexisting resistance is pervasive across diseases that evolve -- like cancer and pathogens -- defying conventional wisdom.
Published Building a roadmap to bioengineer plants that produce their own nitrogen fertilizer
(via sciencedaily.com) Original source Nitrogen fertilizers make it possible to feed the world's growing population, but they are also costly adn harm ecosystems. However, a few plants have evolved the ability to acquire their own nitrogen with the help of bacteria, and a new study helps explain how they did it, not once, but multiple times.
Published Crystals from radioactive metal actinium
(via sciencedaily.com) Original source Researchers grew crystals containing actinium and illuminated them with X-rays to learn how the radioactive metal binds with other elements. That information could help design better cancer treatments.
Published How domestic rabbits become feral in the wild
(via sciencedaily.com) Original source After sequencing the genomes of nearly 300 rabbits from Europe, South America, and Oceania, researchers found that all of them had a mix of feral and domestic DNA. They say this was not what they had expected to find.
Published A better way to make RNA drugs
(via sciencedaily.com) Original source RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste. Researchers report a new, enzyme-based RNA synthesis method that can produce strands of RNA with both natural and modified nucleotides without the environmental hazards.
Published Insight into one of life's earliest ancestors revealed in new study
(via sciencedaily.com) Original source Researchers have shed light on Earth's earliest ecosystem, showing that within a few hundred million years of planetary formation, life on Earth was already flourishing.
Published Scientists create computer program that 'paints' the structure of molecules in the style of Piet Mondrian
(via sciencedaily.com) Original source Scientists have created a computer program that 'paints' the structure of molecules in the style of famous Dutch artist, Piet Mondrian. Researchers are opening eyes and minds to the beauty of molecular structure, as well as posing new questions about the form and function of the molecules themselves.
Published How plant cold specialists can adapt to the environment
(via sciencedaily.com) Original source Evolutionary biologists studied spoonworts to determine what influence genome duplication has on the adaptive potential of plants. The results show that polyploids -- species with more than two sets of chromosomes -- can have an accumulation of structural mutations with signals for a possible local adaptation, enabling them to occupy ecological niches time and time again.
Published Introducing co-cultures: When co-habiting animal species share culture
(via sciencedaily.com) Original source Cooperative hunting, resource sharing, and using the same signals to communicate the same information -- these are all examples of cultural sharing that have been observed between distinct animal species. In a new article, researchers introduce the term 'co-culture' to describe cultural sharing between animal species. These relationships are mutual and go beyond one species watching and mimicking another species' behavior -- in co-cultures, both species influence each other in substantial ways.
Published Nanoplastics and 'forever chemicals' disrupt molecular structures, functionality
(via sciencedaily.com) Original source Researchers have made significant inroads in understanding how nanoplastics and per- and polyfluoroalkyl substances (PFAS) -- commonly known as forever chemicals -- disrupt biomolecular structure and function. The work shows that the compounds can alter proteins found in human breast milk and infant formulas -- potentially causing developmental issues downstream.
Published Pumpkin disease not evolving, could make a difference for management
(via sciencedaily.com) Original source The pathogen that causes bacterial spot is very good at what it does. Forming small lesions on the rinds of pumpkins, melons, cucumbers, and other cucurbits, it mars the fruits' appearance and ushers in secondary pathogens that lead to rot and severe yield loss. The bacterium, Xanthomonas cucurbitae, is so successful that it has had no reason to evolve through time or space.
Published Atlas of proteins reveals inner workings of cells
(via sciencedaily.com) Original source Researchers discover how proteins behave inside cells using AI, which has the potential to guide drug design.
Published Not so simple: Mosses and ferns offer new hope for crop protection
(via sciencedaily.com) Original source Mosses, liverworts, ferns and algae may offer an exciting new research frontier in the global challenge of protecting crops from the threat of disease.
Published Tackling the challenge of coca plant ID: Wild vs cultivated for cocaine
(via sciencedaily.com) Original source A new paper reveals that it's not as straightforward as it might seem. Despite decades of data collection by the United Nations Office on Drugs and Crime (UNODC), which has been valuable to monitor changes in areas occupied by illegal coca plantations in South America, there is no reliable scientific method to distinguish between different types of coca plants.