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Categories: Biology: Evolutionary, Engineering: Nanotechnology
Published GPS nanoparticle platform precisely delivers therapeutic payload to cancer cells
(via sciencedaily.com) Original source A newly developed 'GPS nanoparticle' injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers. They tested their approach in human cell lines and in mice to effectively knock down a cancer-causing gene, reporting that the technique may potentially offer a more precise and effective treatment for notoriously hard-to-treat basal-like breast cancers.
Published Breakthrough in nanostructure technology for real-time color display
(via sciencedaily.com) Original source New groundbreaking technology enables the real-time display of colors and shapes through changes in nanostructures.
Published Anemonefish are better taxonomists than humans
(via sciencedaily.com) Original source Scientists reveal new lineages of giant sea anemones in Japan and their surprising associations with anemonefish.
Published Combined microscopy technique catches light-driven polymers in the act
(via sciencedaily.com) Original source Researchers have used tip-scan high-speed atomic force microscopy combined with an optical microscope to observe light-induced deformation of azo-polymer films. The process could be followed in real time, and the film patterns were found to change with the polarization of the light source. The observations will contribute to the use of azo-polymers in applications such as optical data storage, and the approach is expected to be useful across materials science and physical chemistry.
Published New study discovers how altered protein folding drives multicellular evolution
(via sciencedaily.com) Original source Researchers have discovered a mechanism steering the evolution of multicellular life. They identified how altered protein folding drives multicellular evolution.
Published Evolutionary nature of animal friendships
(via sciencedaily.com) Original source Biologists present groundbreaking research shedding new light on the evolution of social bonds and cooperation among group-living animals.
Published The Malaria parasite generates genetic diversity using an evolutionary 'copy-paste' tactic
(via sciencedaily.com) Original source All modern Plasmodium falciparum, the deadliest malaria parasite in humans, are descendants of one initial infection and so are very closely related, with relatively limited genetic differences. A long-standing mystery in the field has revolved around a very few locations in the P. falciparum genome where there are 'spikes' of mutations -- far more than anywhere else. Researchers have identified two genes in which these unusual mutation spikes result from DNA being copied and pasted from one gene to another.
Published Early life adversity leaves long-term signatures in baboon DNA
(via sciencedaily.com) Original source Early experiences in an animal's life can have a significant impact on its capacity to thrive, even years or decades later, and DNA methylation may help record their effects. In a study of 256 wild baboons, researchers found that resource limitation during early life was associated with many differences in DNA methylation, a small chemical mark on the DNA sequence that can affect gene activity.
Published The world's most prolific CO2-fixing enzyme is slowly getting better
(via sciencedaily.com) Original source New research has found that rubisco -- the enzyme that fuels all life on Earth -- is not stuck in an evolutionary rut after all. The largest analysis of rubisco ever has found that it is improving all the time -- just very, very slowly. These insights could potentially open up new routes to strengthen food security.
Published Revealing the evolutionary origin of genomic imprinting
(via sciencedaily.com) Original source Some of our genes can be expressed or silenced depending on whether we inherited them from our mother or our father. The mechanism behind this phenomenon, known as genomic imprinting, is determined by DNA modifications during egg and sperm production.
Published Synthetic gene helps explain the mysteries of transcription across species
(via sciencedaily.com) Original source 'Random DNA' is naturally active in the one-celled fungi yeast, while such DNA is turned off as its natural state in mammalian cells, despite their having a common ancestor a billion years ago and the same basic molecular machinery, a new study finds.
Published New type of nanoparticle makes vaccines more powerful
(via sciencedaily.com) Original source A type of nanoparticle called a metal organic framework (MOF) could be used to deliver vaccines and act as an adjuvant. Researchers find these particles provoke a strong immune response by activating the innate immune system through cell proteins called toll-like receptors.
Published Aluminum nanoparticles make tunable green catalysts
(via sciencedaily.com) Original source A nanotechnology pioneer has uncovered a transformative approach to harnessing the catalytic power of aluminum nanoparticles by annealing them in various gas atmospheres at high temperatures.
Published Tiny worms tolerate Chornobyl radiation
(via sciencedaily.com) Original source A new study finds that exposure to chronic radiation from Chornobyl has not damaged the genomes of microscopic worms living there today -- which doesn't mean that the region is safe, the scientists caution, but suggests that these worms are exceptionally resilient.
Published Using light to precisely control single-molecule devices
(via sciencedaily.com) Original source Researchers flip the switch at the nanoscale by applying light to induce bonding for single-molecule device switching.
Published Researchers closing in on genetic treatments for hereditary lung disease, vision loss
(via sciencedaily.com) Original source Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions like cystic fibrosis and inherited vision loss.
Published 'Like a lab in your pocket' -- new test strips raise game in gene-based diagnostics
(via sciencedaily.com) Original source Biosensing technology developed by engineers has made it possible to create gene test strips that rival conventional lab-based tests in quality.
Published Modeling the origins of life: New evidence for an 'RNA World'
(via sciencedaily.com) Original source Scientists provide fresh insights on the origins of life, presenting compelling evidence supporting the 'RNA World' hypothesis. The study unveils an RNA enzyme that can make accurate copies of other functional RNA strands, while also allowing new variants of the molecule to emerge over time. These remarkable capabilities suggest the earliest forms of evolution may have occurred on a molecular scale in RNA, and also bring scientists one step closer to re-creating autonomous RNA-based life in the laboratory.
Published An evolutionary mystery 125 million years in the making
(via sciencedaily.com) Original source Plant biologists have uncovered an evolutionary mystery over 100 million years in the making. It turns out that sometime during the last 125 million years, tomatoes and Arabidopsis thaliana plants experienced an extreme genetic makeover. Just what happened remains unclear. But the mystery surrounds CLV3, a gene key to healthy plant growth and development.
Published Spontaneous curvature the key to shape-shifting nanomaterials
(via sciencedaily.com) Original source Inspired by nature, nanotechnology researchers have identified 'spontaneous curvature' as the key factor determining how ultra-thin, artificial materials can transform into useful tubes, twists and helices.