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Categories: Biology: Developmental, Biology: Evolutionary
Published World's first successful embryo transfer in rhinos paves the way for saving the northern white rhinos from extinction



Scientists have succeeded in achieving the world's first pregnancy of a rhinoceros after an embryo transfer. The southern white rhino embryo was produced in vitro from collected egg cells and sperm and transferred into a southern white rhino surrogate mother at the Ol Pejeta Conservancy in Kenya on September 24, 2023. The BioRescue team confirmed a pregnancy of 70 days with a well-developed 6.4 cm long male embryo. The successful embryo transfer and pregnancy are a proof of concept and allow to now safely move to the transfer of northern white rhino embryos -- a cornerstone in the mission to save the northern white rhino from extinction.
Published DNA from preserved feces reveals ancient Japanese gut environment



DNA from ancient feces can offer archaeologists new clues about the life and health of Japanese people who lived thousands of years ago, according to a new study.
Published Ancient brown bear genomes sheds light on Ice Age losses and survival



The brown bear is one of the largest living terrestrial carnivores, and is widely distributed across the Northern Hemisphere. Unlike many other large carnivores that went extinct at the end of the last Ice Age (cave bear, sabretoothed cats, cave hyena), the brown bear is one of the lucky survivors that made it through to the present. The question has puzzled biologists for close to a century -- how was this so?
Published New tool reveals gene behavior in bacteria



Researchers showed that the way in which genes are turned on and off as bacteria grow provide clues to their regulation.
Published Complex green organisms emerged a billion years ago



Of all the organisms that photosynthesize, land plants have the most complex form. How did this morphology emerge? A team of scientists has taken a deep dive into the evolutionary history of morphological complexity in streptophytes, which include land plants and many green algae. Their research allowed them to go back in time to investigate lineages that emerged long before land plants existed.
Published New research guides mathematical model-building for gene regulatory networks



A newly published study provides guidance for building accurate mathematical models for gene regulatory networks.
Published Endless biotechnological innovation requires a creative approach



Scientists working on biological design should focus on the idiosyncrasies of biological systems over optimization, according to new research.
Published A window into plant evolution: The unusual genetic journey of lycophytes



An international team of researchers has uncovered a remarkable genetic phenomenon in lycophytes, which are similar to ferns and among the oldest land plants. Their study reveals that these plants have maintained a consistent genetic structure for over 350 million years, a significant deviation from the norm in plant genetics.
Published How does one species become many?



A global team of biologists has compiled nearly two decades of field data -- representing the study of more than 3,400 Darwin's finches in the Galapagos Islands -- to identify the relationship between beak traits and the longevity of individual finches from four different species.
Published DNA construction led to unexpected discovery of important cell function



Researchers have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new avenues for understanding how the Notch signalling pathway works and how it is involved in several serious diseases.
Published Why animals shrink over time explained with new evolution theory



The new theoretical research proposes that animal size over time depends on two key ecological factors.
Published Study throws our understanding of gene regulation for a loop



To function properly, the genetic material is highly organized into loop structures that often bring together widely separated sections of the genome critical to the regulation of gene activity. Scientists now address how these loops can help repress or silence gene activity, with potentially far-reaching effects on human health.
Published Machine learning reveals sources of heterogeneity among cells in our bodies



A team of scientists discovered the secrets of cell variability in our bodies. The findings of this research are expected to have far-reaching effects, such as improvement in the efficacy of chemotherapy treatments, or set a new paradigm in the study of antibiotic-resistant bacteria.
Published Surprisingly simple model explains how brain cells organize and connect



A new study by physicists and neuroscientists describes how connectivity among neurons comes about through general principles of networking and self-organization, rather than the biological features of an individual organism.
Published Pacific kelp forests are far older that we thought



Fossils of kelp along the Pacific Coast are rare. Until now, the oldest fossil dated from 14 million years ago, leading to the view that today's denizens of the kelp forest -- marine mammals, urchins, sea birds -- coevolved with kelp. A recent amateur discovery pushes back the origin of kelp to 32 million years ago, long before these creatures appeared. A new analysis suggests the first kelp grazers were extinct, hippo-like animals called desmostylians.
Published Feeding mode of ancient vertebrate tested for first time



A feeding method of the extinct jawless heterostracans, among the oldest of vertebrates, has been examined and dismissed by scientists, using fresh techniques.
Published Candida evolution disclosed: New insights into fungal infections



Identification of genes under recent selection provides insights into the molecular mechanisms of human-related adaptation in Candida pathogens. The study reveals both known and novel genetic variants associated with drug resistance, offering potential targets for improved antifungal therapies.
Published Bioinformatics: Researchers develop a new machine learning approach



To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and artificial intelligence (AI) to develop a machine learning approach that can predict the efficacy of CRISPR technologies more accurately than before.
Published 3D in vitro human atherosclerosis model for high-throughput drug screening



A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, researchers report.
Published Researchers create light-powered yeast, providing insights into evolution, biofuels, cellular aging



Researchers have engineered one of the world's first yeast cells able to harness energy from light, expanding our understanding of the evolution of this trait -- and paving the way for advancements in biofuel production and cellular aging.