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Categories: Biology: Developmental, Biology: Evolutionary
Published These robots helped explain how insects evolved two distinct strategies for flight



Robots helped achieve a major breakthrough in our understanding of how insect flight evolved. The study is a result of a six-year long collaboration between roboticists and biophysicists.
Published Avatars to help tailor glioblastoma therapies



Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study.
Published Scientists develop 3D printing method that shows promise for repairing brain injuries



Researchers have produced an engineered tissue representing a simplified cerebral cortex by 3D printing human stem cells. When implanted into mouse brain slices, the structures became integrated with the host tissue. The technique may ultimately be developed into tailored repairs to treat brain injuries.
Published When cells go boom: Study reveals inflammation-causing gene carried by millions



Researchers have found that a genetic change that increases the risk of inflammation, through a process described as ‘explosive’ cell death, is carried by up to 3% of the global population.
Published Scientists identify evolutionary gateway helping pneumonia bacteria become resistant to antibiotics



An evolutionary gateway which helps pneumonia cells become resistant to antibiotics has been discovered.
Published How new plant cell walls change their mechanical properties after cell division



Scientists reveal new plant cell walls can have significantly different mechanical properties compared to surrounding parental cell walls, enabling cells to change their local shape and influence the growth of plant organs.
Published Preventing spread of parasitic DNA in our genomes



Researchers have identified a new enzyme called PUCH, which plays a key role in preventing the spread of parasitic DNA in our genomes. These findings may reveal new insights into how our bodies detect and fight bacteria and viruses to prevent infections.
Published Genetics of attraction: Mate choice in fruit flies



Genetic quality or genetic compatibility? What do female fruit flies prioritize when mating? Researchers show that both factors are important at different stages of the reproductive process and that females use targeted strategies to optimize the fitness of their offspring.
Published A hygiene program for chromosomes



Researchers identified and characterized a new cellular compartment in vertebrate cells that might be a precursor of today's eucaryotic nucleus. The study reveals that mammalian cells recognize, cluster, sort and keep extrachromosomal DNA -- like transfected plasmid DNA and endogenous circular DNAs originating from telomeres of the chromosome -- away from chromosomal DNA. That suggests that there is a cell autonomous genome defense system.
Published A more effective experimental design for engineering a cell into a new state



A new machine-learning approach helps scientists more efficiently identify the optimal intervention to achieve a certain outcome in a complex system, such as genome regulation, requiring far fewer experimental trials than other methods.
Published Researchers studied thousands of fertility attempts hoping to improve IVF



By genetically testing nearly one thousand embryos, scientists have provided the most detailed analysis of embryo fate following human in vitro fertilization.
Published Genome study reveals 30 years of Darwin's finch evolution



An international team of researchers has released a landmark study on contemporary evolutionary change in natural populations. Their study uses one of the largest genomic datasets ever produced for animals in their natural environment, comprising nearly 4,000 Darwin's finches. The study has revealed the genetic basis of adaptation in this iconic group.
Published Insights into early snake evolution through brain analysis



Recent study sheds new light on the enigmatic early evolution of snakes by examining an unexpected source: their brains. The results emphasize the significance of studying both the soft parts of animals’ bodies and their bones for understanding how animals evolved.
Published Explosion in fish biodiversity due to genetic recycling



The rapid formation of 500 different species of fish in a single lake, each with specialized ecological roles, resulted from a small but genetically diverse hybrid population.
Published Timing plant evolution with a fast-ticking epigenetic clock



Recent discoveries in the field of epigenetics, the study of inheritance of traits that occur without changing the DNA sequence, have shown that chronological age in mammals correlates with epigenetic changes that accumulate during the lifetime of an individual. In humans, this observation has led to the development of epigenetic clocks, which are now extensively used as biomarkers of aging. While these clocks work accurately from birth until death, they are set back to zero in each new generation. Now, an international team shows that epigenetic clocks not only exist in plants, but that these clocks keep ticking accurately over many generations.
Published Did animal evolution begin with a predatory lifestyle?



Surprising findings on the development of sea anemones suggest that a predatory lifestyle molded their evolution and had a significant impact on the origin of their nervous system. The researchers were able to show that the young life stages (larvae) of the small sea anemone Aiptasia actively feed on living prey and are not dependent on algae. To capture its prey, the anemone larvae use specialized stinging cells and a simple neuronal network.
Published A lethal parasite's secret weapon: Infecting non-immune cells



The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.
Published Fish reveal cause of altered human facial development



Some substances in medicines, household items and the environment are known to affect prenatal child development. Researchers tested the effects of five drugs (including caffeine and the blood thinner warfarin) on the growth of zebrafish embryos. They found that all five had the same effect, impairing the migration of bone-forming cells which resulted in the onset of facial malformation. Zebrafish embryos grow quickly, are transparent and develop outside of the parent's body, making them ideal for studying early development. A zebrafish-based system could be used to easily screen for potentially harmful substances, reducing animal testing on mammals and supporting parents-to-be when making choices for themselves and their baby.
Published A turtle time capsule: DNA found in ancient shell



Paleontologists discover possible DNA remains in fossil turtle that lived 6 million years ago in Panama, where continents collide.
Published Vision in the brain: Hardwired for action



Brain circuits for vision develop without any kind of input from the retina in zebrafish.