Showing 20 articles starting at article 661

< Previous 20 articles        Next 20 articles >

Categories: Biology: Developmental, Biology: Evolutionary

Return to the site home page

     (via sciencedaily.com)     Original source 

The NSL (non-specific lethal) complex regulates thousands of genes in fruit flies and mammals. Silencing the NSL genes leads to the death of the organism, which gave the complex its curious name. Researchers have now discovered that the genes regulated by the NSL complex also include genes of the intraciliary transport system. This enables different cell types to form cilia on their surface, which are important for cell communication. The study shows that these genes are 'switched on' by the NSL complex, regardless of whether a particular cell has cilia or not. The researchers found that this class of cilia-associated genes is crucial for the function of podocytes. This is a highly specialized cell type of the kidney that, paradoxically, does not have cilia. These findings have important implications for ciliopathies and kidney disease.

     (via sciencedaily.com)     Original source 

A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens. A new study sheds light on the mechanisms involved in the complex interplay between taste perception and immune function. Their work also highlights the potential of a sequencing tool for investigating epigenetic mechanisms that affect taste-cell gene expression.

     (via sciencedaily.com)     Original source 

Researchers have discovered a novel approach for engrafting engineered cells into injured lung tissue. These findings may lead to new ways for treating lung diseases, such as emphysema, pulmonary fibrosis and COVID-19. The two studies describe the methodologies for engineering lung stem cells and transplanting them into injured experimental lungs without immunosuppression.

     (via sciencedaily.com)     Original source 

Researchers have discovered how proteins work in tandem to regulate 'treadmilling', a mechanism used by the network of microtubules inside cells to ensure proper cell division.

     (via sciencedaily.com)     Original source 

A researcher made a discovery that could change our understanding of the universe. He reveals that there is a range in which fundamental constants can vary, allowing for the viscosity needed for life processes to occur within and between living cells. This is an important piece of the puzzle in determining where these constants come from and how they impact life as we know it.

     (via sciencedaily.com)     Original source 

New research suggests that natural selection, famous for rewarding advantageous differences in organisms, can also preserve similarities. The researchers worked with a plant called wild radish and its stamens, or pollen-producing parts, two of which are short and four are long. Roughly 55 million years ago, wild radish ancestors had stamens of equal length. The team selectively bred -- or artificially selected -- wild radish to reduce the difference in stamen length and return the plant to a more ancestral look. This shows that today's wild radish and, likely, its family members still have the requisite genetic variability to evolve, but natural selection is preserving its different stamen lengths.

     (via sciencedaily.com)     Original source 

Regulatory genes -- genes that control how other genes are used -- are responsible for 69% of the heritability of dairy cattle traits such as milk production and fertility, according to a new study. This contribution is 44% more than expected and much higher than previous studies of regulatory genes in humans. The findings, reported by a team of animal and human geneticists, could improve the efficiency of agricultural breeding programs. The study also helps solve the longstanding mystery of why mammalian genomes contain so much noncoding DNA.

     (via sciencedaily.com)     Original source 

Many plants and crops rely on insects to pollinate them so they can reproduce. A new study has shown that several flowering plants from the group Euonymus are pollinated by fungus gnats, a dipteran insect. Specifically, they pollinate Euonymus plants which have red-petaled flowers with short stamens and yogurt-like scent. Although fungus gnats are known to pollinate hundreds of plant species, this study shows that the particular traits of red Euonymus flowers were likely to have been acquired via pollination syndrome, evolving over a process of natural selection to be pollinated specifically by fungus gnats. This research highlights the important role of Diptera, which are commonly regarded as pests, in plant diversity and evolution.

     (via sciencedaily.com)     Original source 

New research shows that a single mutation that has immediate effects on plant fitness is maintained over the long term in natural plant populations, despite theories predict the contrary. The researchers located and identified the gene that regulates the amount of an active defense hormone. Mutants in this gene are susceptible to herbivore attack. However, they compensate for impaired defenses through robust genetic networks. When fewer herbivores attack, they even grow faster and produce more offspring.

     (via sciencedaily.com)     Original source 

Researchers model and map how neurons across the tiny brain of a C. elegans worm encode its behaviors, revealing many new insights about the robustness and flexibility of its nervous system.

     (via sciencedaily.com)     Original source 

Genetic remnants of viruses that are naturally present in the human genome could affect the development of neurodegenerative diseases. Researchers come to this conclusion on the basis of studies on cell cultures.

     (via sciencedaily.com)     Original source 

An extremely rare collection of 160-million-year-old sea spider fossils from Southern France are closely related to living species, unlike older fossils of their kind.

     (via sciencedaily.com)     Original source 

Can you recognize an old friend, but forget what you had for breakfast yesterday? Our brains constantly rearrange their circuitry to retain information, but the molecular basis behind this process isn't well understood. New research suggests that complex sugars called glycosaminoglycans might play a major role in the 'plasticity' of the brains of mice and could be used to repair neural connections after injury.

     (via sciencedaily.com)     Original source 

A new method allows large quantities of muscle stem cells to be safely obtained in cell culture. This provides a potential for treating patients with muscle diseases -- and for those who would like to eat meat, but don't want to kill animals.

     (via sciencedaily.com)     Original source 

The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of full-strength signals between neurons, according to a new study.

     (via sciencedaily.com)     Original source 

Biologists discovered that a scaffolding protein called TCOF1 is responsible for the formation of a biomolecular condensate called the fibrillar center, which forms within the cell nucleolus.

     (via sciencedaily.com) 

Researchers have developed a new algorithm for recovering the 3D refractive index distribution of biological samples that exhibit multiple types of light scattering.

     (via sciencedaily.com) 

A mathematical model provides new insights into the distribution of genetic information during bacterial cell division

     (via sciencedaily.com)     Original source 

A new study shows that the cheek teeth of proboscideans (elephants and their ancient relatives) evolved in response to dietary changes due to vegetation changes and climate change in East Africa during the last 26 million years.

     (via sciencedaily.com)     Original source 

Scientists have constructed a comprehensive 'super-pangenome' for watermelon and its wild relatives, uncovering beneficial genes lost during domestication that could improve disease resistance and fruit quality of this vital fruit crop.