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Categories: Biology: Developmental, Biology: Evolutionary

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The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques.

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A new study has found that genetic improvement is underlying the increasing speed of Britain's thoroughbreds. This contrasts with earlier studies that suggested racehorses were showing no genetic improvement in response to selection by breeders.

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Researchers have identified three 4,000-year-old British cases of Yersinia pestis, the bacteria causing the plague -- the oldest evidence of the plague in Britain to date.

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Applying imaging technology to plant roots, researchers have developed a new understanding of chemicals that are responsible for plant growth. The chemical 'roadmap' identifies where key molecules are distributed along corn roots and how their placement factors into the plant's maturation.

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A new study of the freshwater greenfin darter fish suggests river erosion can be a driver of biodiversity in tectonically inactive regions.

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The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates.

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A new tool which could help reduce the spread of antimicrobial resistance is showing early promise, through exploiting a bacterial immune system as a gene editing tool.

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Species known as marine habitat-forming species -- gorgonians, corals, algae, seaweeds, marine phanerogams, etc.-- are organisms that help generate and structure the underwater landscapes. These are natural refuges for other species, and provide biomass and complexity to the seabeds. But these key species in marine ecosystems are currently threatened by climate change and other perturbations derived from human activity. Now, a study warns that even in the marine protected areas (MPAs) the genetic diversity of structural species is not protected, although it is essential for the response and adaptation of populations to changes that alter the natural environment.

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Scientists have uncovered new clues about the origin of paired appendages -- a major evolutionary step that remains unresolved and highly debated.

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Research has revealed features of early human brain development are mimicked in the brains of marsupials.

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A team of researchers has found a mechanism in thale cress (Arabidopsis thaliana) which enables plants to provide protection against salt stress for their sensitive stem cells in the meristem at the root tip.

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Researchers were able to identify changes in the accessibility (that is, the 'readability') of transposable elements. To do this, the researchers used an approach combining various sets of multiomics data, which characterize and quantify collections of biomolecules in cells or organisms. One was the transcriptome, which consists of all copies of RNA transcribed from DNA in the cell. The other was the epigenome, which is the collection of chemical changes to DNA that modify gene expression. An advantage of this multiomics approach is that they were able to identify families of transposable elements with changes in accessibility, which would have likely been missed by previous approaches.

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Understanding that others hold different viewpoints from your own is essential for human sociality. Adopting another person's visual perspective is a complex skill that emerges around the age of two. A new study suggests that this ability first arose in dinosaurs, at least 60 million years before it appeared in mammals. These findings challenge the idea that mammals were the originators of novel and superior forms of intelligence in the wake of the dinosaur extinction.

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Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests. One of the greatest challenges in modern plant research is to identify the differences in genetic information that are responsible for this variation.

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Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. Botanists have demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to the research team leader.

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Biophysicists have designed a new cell-like transport system that represents an important milestone on the road to artificial cells.

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Scientists have discovered a new species of mosasaur, a sea-dwelling lizard from the age of the dinosaurs, with strange, ridged teeth unlike those of any known reptile. Along with other recent finds from Africa, it suggests that mosasaurs and other marine reptiles were evolving rapidly up until 66 million years ago, when they were wiped out by an asteroid along with the dinosaurs and around 90% of all species on Earth.

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Scales, spines, feathers and hair are examples of vertebrate skin appendages, which constitute a remarkably diverse group of micro-organs. Despite their natural multitude of forms, these appendages share early developmental processes at the embryonic stage. Researchers have discovered how to permanently transform the scales that normally cover the feet of chickens into feathers, by specifically modifying the expression of certain genes.

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Surprisingly, genome comparisons have failed to resolve a major question in animal evolution: Which living animals are the descendants of the earliest animals to evolve in the world's oceans? Scientists performed a detailed chromosomal analysis that comes down definitively in favor of comb jellies, or ctenophores, as the most recent common ancestor of all animals, or the sister taxa to all animals. Sponges evolved later.

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A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.